Peptide
Collagen Peptides
Hydrolyzed collagen protein fragments used to support skin elasticity, joint health, and connective tissue repair.
Emerging Research Peptide
BPC-157
BPC-157 (Body Protection Compound-157) is a synthetic peptide consisting of 15 amino acids derived from a protective protein found in human gastric juice. It was first isolated by researchers studying the mechanisms behind the stomach's remarkable ability to heal itself despite constant exposure to hydrochloric acid and digestive enzymes. Animal studies have demonstrated accelerated healing of tendons, ligaments, muscles, nerves, and the gastrointestinal tract. The proposed mechanisms include upregulation of growth hormone receptors, promotion of angiogenesis (new blood vessel formation), modulation of the nitric oxide system, and interaction with the FAK-paxillin pathway involved in tissue repair. Despite promising preclinical data, human clinical trials remain limited. Most evidence comes from rodent models, and the peptide's regulatory status varies by country. It is not FDA-approved for any medical condition. Users in the biohacking and athletic recovery communities report benefits for joint injuries, gut healing, and tendon repair, but these remain anecdotal.
Updated March 1, 2026This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication regimen.
Benefits & Uses
Accelerated tendon and ligament healing in animal models. Gastroprotective effects including ulcer healing and reduced intestinal inflammation. Potential neuroprotective properties. May support angiogenesis and tissue repair pathways.
Side Effects & Precautions
Generally well-tolerated in animal studies with a very wide therapeutic window. Reported human side effects are rare but include mild nausea, dizziness, and injection site reactions. Long-term human safety data is lacking.
Dosage & Administration
Typical protocols in the biohacking community use 250-500mcg once or twice daily, administered subcutaneously near the injury site or orally for GI applications. Cycles of 4-8 weeks are common. No standardized medical dosing exists due to lack of human clinical trials.
Contraindications
Active cancer or history of cancer (due to angiogenesis promotion). Pregnancy and breastfeeding. Not FDA-approved — regulatory status varies by jurisdiction. Should not replace standard medical treatment for serious injuries.
Known Interactions
| Substance | Type | Severity | Description |
|---|---|---|---|
| Blood thinners (warfarin, heparin) | moderate | BPC-157 may affect platelet aggregation and vascular function through its nitric oxide modulation. Concurrent use with anticoagulants could theoretically alter bleeding risk. Medical supervision recommended. | |
| NSAIDs (ibuprofen, naproxen) | minor | BPC-157 has gastroprotective effects that may actually counteract NSAID-induced GI damage. Some practitioners use them concurrently intentionally, but the interaction is not fully characterized in humans. |
Sources
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Emerging Research Health Disclaimer
This content is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement or medication regimen.