Sulfonylurea derivatives are a class of antidiabetic drugs that are used in the management of diabetes mellitus type 2 ("adult-onset"). They act by increasing insulin release from the beta cells in the pancreas. Drugs in this class First generation: Chlorpropamide Tolbutamide Tolazamide Second generation: Glipizide Gliclazide Glibenclamide (glyburide) Glimepiride Gliquidone Chemistry Please see individual members of the class for their chemical structure All sulfonylureas have a ce ...
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