Interferon beta-1b - Article Betaseron
Article: Interferon beta-1b
|Systematic (IUPAC) name|
|Human interferon beta|
|Mol. weight||20011.0 g/mol|
|Pregnancy cat.|| |
Interferon beta-1b (marketed as Betaseron) is a drug in the interferon family used to treat multiple sclerosis. It is administered by sub-cutaneous injection and has been shown to slow the advance of the affliction as well as reduce the frequency of attacks. Betaseron is manufactured by Berlex Corporation.
It is believed that Interferon-Beta based drugs achieve their beneficial effect on MS progress via their anti-inflammatory properties. Studies have also determined that Interferon-Beta improves the integrity of the blood-brain barrier (BBB)â€”which generally breaks down in MS patients, allowing increasing amounts of undesirable substances to reach the brain. This strengthening of the BBB may be a contributing factor to Interferon-Beta's beneficial effects. These studies were carried out in vitro (outside a living organism - a "petri dish" experiment), so it does not necessarily mean it works the same in people.
Betaseron costs approximately US$1300 for 0.3 mg solution, or equivalent to 15 vials. 
- Interferon beta-1a
- Multiple sclerosis