... VERAPAMIL (Calan® SR, Covera-HS®, Isoptin® SR, Verelan®, Verelan®-PM) is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This results in relaxation of blood vessels, which can reduce the amount of work the heart has to do. Sustained-release verapamil helps reduce high blood pressure (hypertension) It is not a cure. Generic verapamil sustained-release tablets are available. It is not a good idea to change the brand of your sustained-release product. Your body may respond differently. If you do switch between products you will need careful supervision from your prescriber or health care professional. ...
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Verapamil Systematic (IUPAC) name 2-(3,4-dimethoxyphenyl)-5-[2-(3,4- dimethoxyphenyl)ethyl-methyl-amino] -2-(1-methylethyl)pentanenitrile Identifiers CAS number 52-53-9 ATC code C08DA01 PubChem 62969 DrugBank APRD00335 Chemical data Formula C27H38N2O4 Mol. weight 454.602 g/mol Pharmacokinetic data Bioavailability 35.1% Metabolism Hepatic Half life 2.8-7.4 hours Excretion Renal: 11% Therapeutic considerations Pregnancy cat. C: (USA) Legal status ? ...
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