Lupus Anticoagulant Information and Side Effects
Lupus anticoagulant is an autoimmune disorder caused by antibodies that bind to phospholipids and proteins associated with the cell membrane. This antibody has the peculiar nature of causing a delay in coagulation in laboratory tests (the partial thromboplastin time) while clinically predisposing for thrombosis. It is also known as lupus antibody, LA and lupus inhibitor. Together with anticardiolipin antibodies, LA causes the bulk of antiphospholipid syndrome.
... Why get tested?
To help evaluate a prolonged activated partial thromboplastin time (aPTT) and/or a thrombotic episode, to help determine the cause of recurrent fetal loss, as part of an evaluation for antiphospholipid syndrome. Not a diagnostic test for lupus.
When to get tested?
When you have a prolonged aPTT test. When you have had a venous or arterial thromboembolism. When you have had recurrent miscarriages, especially in the 2nd and 3rd trimesters.
A blood sample is obtained by inserting a needle into a vein in the arm.
- Lupus Anticoagulant (Lab Tests Online)