Clinical Trial: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Hodgkin's or Non-Hodgkin's Lymphoma

This study is no longer recruiting patients.

Sponsors and Collaborators: Children's Oncology Group
National Cancer Institute (NCI)
Information provided by: National Cancer Institute (NCI)

Purpose

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy and kill more cancer cells.

PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy followed by peripheral stem cell transplantation in treating children who have recurrent or refractory Hodgkin's lymphoma or non-Hodgkin's lymphoma.

Condition Treatment or Intervention Phase
recurrent childhood lymphoblastic lymphoma
childhood diffuse large cell lymphoma
childhood immunoblastic large cell lymphoma
recurrent/refractory childhood Hodgkin's lymphoma
recurrent childhood small noncleaved cell lymphoma
recurrent childhood large cell lymphoma
 Drug: carmustine
 Drug: cyclophosphamide
 Drug: etoposide
 Drug: mesna
 Procedure: biological response modifier therapy
 Procedure: bone marrow ablation with stem cell support
 Procedure: chemotherapy
 Procedure: peripheral blood stem cell transplantation
Phase II

MedlinePlus related topics:  Cancer;   Cancer Alternative Therapy;   Lymphatic Diseases;   Lymphoma

Study Type: Interventional
Study Design: Treatment

Official Title: Phase II Pilot Study of Peripheral Blood Stem Cell Transplantation After Preparative Therapy Consisting of Cyclophosphamide, Carmustine, and Etoposide in Patients With Recurrent and Primarily Refractory Hodgkin's and Non-Hodgkin's Childhood Lymphoma

Further Study Details: 

OBJECTIVES:

OUTLINE: Patients receive 2 courses of reinduction chemotherapy followed by bone marrow biopsy and aspirate prior to peripheral blood stem cell (PBSC) harvest. If marrow involvement is still present at harvest, then 2 additional courses of induction chemotherapy are given.

The PBSC transplantation preparative regimen should begin within 2 weeks of completing reinduction therapy course, consisting of the following:

PROJECTED ACCRUAL: A total of 30 patients will be accrued in each subgroup.

Eligibility

Ages Eligible for Study:  1 Year   -   21 Years,  Genders Eligible for Study:  Both

Criteria

DISEASE CHARACTERISTICS:

PATIENT CHARACTERISTICS: Age:

  • 1 to 21 (at initial diagnosis)

Performance status:

  • Not specified

Life expectancy:

  • Not specified

Hematopoietic:

  • Not specified

Hepatic:

  • SGOT or SGPT less than 2.5 times normal
  • Bilirubin no greater than 1.5 mg/dL

Renal:

  • Creatinine less than 1.5 mg/dL
  • Glomerular filtration rate greater than 60 mL/min as measured by radionuclide scan or 24 hour urine collection for creatinine clearance

Cardiovascular:

  • Shortening fraction of at least 28% by echocardiogram
  • Ejection fraction of at least 40% by radionuclide angiogram echocardiogram

Pulmonary:

  • Total lung capacity (TLC) at least 50% OR
  • Vital capacity (VC) at least 65% of normal
  • DLCO at least 55% of normal
  • For children who are uncooperative to pulmonary function testing, no dyspnea at rest or with mild exercise, and a pulse oximetry of at least 95%

Other:

  • HIV negative

PRIOR CONCURRENT THERAPY: Biologic therapy:

  • Not specified

Chemotherapy:

  • See Disease Characteristics

Endocrine therapy:

  • Not specified

Radiotherapy:

  • See Disease Characteristics

Surgery:

  • Not specified

Location Information


Alabama
      University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham,  Alabama,  35233,  United States

      University of South Alabama Medical Center, Mobile,  Alabama,  36604,  United States

Arizona
      Arizona Cancer Center, Tucson,  Arizona,  85724,  United States

      Phoenix Children's Hospital, Phoenix,  Arizona,  85016-7710,  United States

Arkansas
      University of Arkansas for Medical Sciences, Little Rock,  Arkansas,  72205,  United States

California
      Cedars-Sinai Medical Center, Los Angeles,  California,  90048,  United States

      Chao Family Comprehensive Cancer Center, Orange,  California,  92868,  United States

      Children's Hospital Central California, Madera,  California,  93638-8762,  United States

      Children's Hospital Los Angeles, Los Angeles,  California,  90027-0700,  United States

      Children's Hospital of Oakland, Oakland,  California,  94609-1809,  United States

      Children's Hospital of Orange County, Orange,  California,  92868,  United States

      Children's Hospital San Diego, San Diego,  California,  92123-4282,  United States

      City of Hope Comprehensive Cancer Center, Duarte,  California,  91010-3000,  United States

      David Grant Medical Center, Travis Air Force Base,  California,  94535,  United States

      Jonathan Jaques Children's Cancer Center, Long Beach,  California,  90801-1428,  United States

      Jonsson Comprehensive Cancer Center, UCLA, Los Angeles,  California,  90095-1781,  United States

      Kaiser Permanente Medical Center - San Francisco Geary Campus, San Francisco,  California,  94115,  United States

      Kaiser Permanente Medical Center - Santa Clara, Santa Clara,  California,  95051-5386,  United States

      Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego, San Diego,  California,  92120,  United States

      Loma Linda University Medical Center, Loma Linda,  California,  92354,  United States

      Lucile Packard Children's Hospital at Stanford, Palo Alto,  California,  94304,  United States

      Rebecca and John Moores UCSD Cancer Center, La Jolla,  California,  92093-0658,  United States

      Santa Barbara Cottage Hospital, Santa Barbara,  California,  93102,  United States

      Southern California Permanente Medical Group, Downey,  California,  90242,  United States

      Sutter Cancer Center, Sacramento,  California,  95816,  United States

      UCSF Comprehensive Cancer Center, San Francisco,  California,  94143-0128,  United States

      University of California Davis Medical Center, Sacramento,  California,  95817,  United States

Colorado
      Childhood Hematology/Oncology Associates, Denver,  Colorado,  80218,  United States

      Children's Hospital of Denver, Denver,  Colorado,  80218-1088,  United States

      Presbyterian-St Luke's Medical Center, Denver,  Colorado,  80218,  United States

Connecticut
      University of Connecticut Health Center, Farmington,  Connecticut,  06360-7106,  United States

      Yale Comprehensive Cancer Center, New Haven,  Connecticut,  06520-8028,  United States

Delaware
      Alfred I. Dupont Institute, Wilmington,  Delaware,  19899,  United States

District of Columbia
      Children's National Medical Center, Washington,  District of Columbia,  20010-2970,  United States

      Lombardi Cancer Center, Washington,  District of Columbia,  20007,  United States

      Walter Reed Army Medical Center, Washington,  District of Columbia,  20307-5000,  United States

Florida
      All Children's Hospital, St. Petersburg,  Florida,  33701,  United States

      Baptist Hospital of Miami, Miami,  Florida,  33176-2197,  United States

      Broward General Medical Center, Fort Lauderdale,  Florida,  33316,  United States

      Children's Hospital of Southwest Florida, Fort Myers,  Florida,  33908,  United States

      Florida Hospital Cancer Institute, Orlando,  Florida,  32803,  United States

      Joe DiMaggio Children's Hospital at Memorial, Hollywood,  Florida,  33021,  United States

      Miami Children's Hospital, Miami,  Florida,  33155-4069,  United States

      Nemours Children's Clinic, Jacksonville,  Florida,  32207,  United States

      Nemours Children's Clinic-Orlando, Orlando,  Florida,  32806,  United States

      Sacred Heart Children's Hospital, Pensacola,  Florida,  32504,  United States

      Shands Hospital and Clinics, University of Florida, Gainesville,  Florida,  32610-100277,  United States

      St. Mary's Hospital, West Palm Beach,  Florida,  33407,  United States

      Tampa Children's Hospital, Tampa,  Florida,  33677-4227,  United States

      University of Miami-Jackson Memorial Hospital, Miami,  Florida,  33136,  United States

Georgia
      Children's Healthcare of Atlanta - Scottish Rite, Atlanta,  Georgia,  30342,  United States

      Emory University Hospital - Atlanta, Atlanta,  Georgia,  30322,  United States

      Medical Center of Central Georgia, Macon,  Georgia,  31201,  United States

      Medical College of Georgia Comprehensive Cancer Center, Augusta,  Georgia,  30912-4000,  United States

      Memorial Health University Medical Center, Inc., Savannah,  Georgia,  31403-3089,  United States

Hawaii
      Cancer Research Center of Hawaii, Honolulu,  Hawaii,  96813,  United States

      MBCCOP - Hawaii, Honolulu,  Hawaii,  96813,  United States

      Tripler Army Medical Center, Honolulu,  Hawaii,  96859-5000,  United States

Idaho
      Mountain States Tumor Institute, Boise,  Idaho,  83712,  United States

Illinois
      Children's Memorial Hospital - Chicago, Chicago,  Illinois,  60614,  United States

      Hope Children's Hospital, Oak Lawn,  Illinois,  60453,  United States

      Lutheran General Hospital, Park Ridge,  Illinois,  60068-1174,  United States

      Rush-Presbyterian-St. Luke's Medical Center, Chicago,  Illinois,  60612,  United States

      Saint Jude Midwest Affiliate, Peoria,  Illinois,  61637,  United States

      Southern Illinois University School of Medicine, Springfield,  Illinois,  62794-9658,  United States

      University of Chicago Cancer Research Center, Chicago,  Illinois,  60601,  United States

      University of Illinois at Chicago, Chicago,  Illinois,  60612,  United States

Indiana
      Indiana University Cancer Center, Indianapolis,  Indiana,  46202-5289,  United States

      St. Vincent Hospital and Health Care Center, Indianapolis,  Indiana,  46260,  United States

Iowa
      Holden Comprehensive Cancer Center, Iowa City,  Iowa,  52242-1009,  United States

      John Stoddard Cancer Center, Des Moines,  Iowa,  50309,  United States

      Raymond Blank Memorial Hospital for Children, Des Moines,  Iowa,  50308,  United States

Kansas
      Wesley Medical Center, Wichita,  Kansas,  67214,  United States

Kentucky
      Albert B. Chandler Medical Center, University of Kentucky, Lexington,  Kentucky,  40536-0284,  United States

      Kosair Children's Hospital, Louisville,  Kentucky,  40202-3830,  United States

Louisiana
      Children's Hospital of New Orleans, New Orleans,  Louisiana,  70118,  United States

      Ochsner Clinic, New Orleans,  Louisiana,  70121,  United States

      Tulane University School of Medicine, New Orleans,  Louisiana,  70112,  United States

Maine
      Eastern Maine Medical Center, Bangor,  Maine,  04401,  United States

      Maine Children's Cancer Program, Scarborough,  Maine,  04074,  United States

Maryland
      Marlene and Stewart Greenebaum Cancer Center, University of Maryland, Baltimore,  Maryland,  21201-1595,  United States

      Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore,  Maryland,  21231-2410,  United States

      Sinai Hospital of Baltimore, Baltimore,  Maryland,  21225,  United States

Massachusetts
      Baystate Medical Center, Springfield,  Massachusetts,  01107,  United States

      Dana-Farber Cancer Institute, Boston,  Massachusetts,  02115,  United States

      Floating Hospital for Children, Boston,  Massachusetts,  02111,  United States

      University of Massachusetts Memorial Medical Center - University Campus, Worcester,  Massachusetts,  01655,  United States

Michigan
      Bronson Methodist Hospital, Kalamazoo,  Michigan,  49007,  United States

      CCOP - Beaumont, Royal Oak,  Michigan,  48073-6769,  United States

      Children's Hospital of Michigan, Detroit,  Michigan,  48201,  United States

      Henry Ford Hospital, Detroit,  Michigan,  48202,  United States

      Hurley Medical Center, Flint,  Michigan,  48503,  United States

      Michigan State University, East Lansing,  Michigan,  48824,  United States

      Mott Children's Hospital, Ann Arbor,  Michigan,  48109-0914,  United States

      Spectrum Health and DeVos Children's Hospital, Grand Rapids,  Michigan,  49503,  United States

      St. John Hospital and Medical Center, Detroit,  Michigan,  48236,  United States

      William Beaumont Hospital, Royal Oak,  Michigan,  48073-6769,  United States

Minnesota
      Children's Hospitals and Clinics - Minneapolis, Minneapolis,  Minnesota,  55404,  United States

      Children's Hospitals and Clinics of Minnesota, Saint Paul,  Minnesota,  55102,  United States

      Mayo Clinic Cancer Center, Rochester,  Minnesota,  55905,  United States

      St. Mary's/Duluth Clinic Cancer Center, Duluth,  Minnesota,  55805-1983,  United States

Mississippi
      University of Mississippi Medical Center, Jackson,  Mississippi,  39216-4505,  United States

Missouri
      Cardinal Glennon Children's Hospital, Saint Louis,  Missouri,  63104,  United States

      Children's Mercy Hospital, Kansas City,  Missouri,  64108,  United States

      St. Louis Children's Hospital, Saint Louis,  Missouri,  63110,  United States

Nebraska
      Children's Hospital of Omaha, Omaha,  Nebraska,  68114,  United States

      University of Nebraska Medical Center, Omaha,  Nebraska,  68198-2168,  United States

Nevada
      Sunrise Hospital and Medical Center, Las Vegas,  Nevada,  89109-2306,  United States

New Hampshire
      Norris Cotton Cancer Center, Lebanon,  New Hampshire,  03756-0002,  United States

New Jersey
      Atlantic Health System, Summit,  New Jersey,  07901,  United States

      Cancer Institute of New Jersey, New Brunswick,  New Jersey,  08903,  United States

      Hackensack University Medical Center, Hackensack,  New Jersey,  07601,  United States

      Newark Beth Israel Medical Center, Newark,  New Jersey,  07112-2094,  United States

      St. Joseph's Hospital and Medical Center, Paterson,  New Jersey,  07503,  United States

New Mexico
      University of New Mexico Cancer Research and Treatment Center, Albuquerque,  New Mexico,  87131,  United States

New York
      Albert Einstein Clinical Cancer Center, Bronx,  New York,  10461,  United States

      Brookdale University Hospital and Medical Center, Brooklyn,  New York,  11212,  United States

      Brooklyn Hospital Center, Brooklyn,  New York,  11201,  United States

      Cancer Center of Albany Medical Center, Albany,  New York,  12208,  United States

      Columbia Presbyterian Hospital, New York,  New York,  10032,  United States

      James P. Wilmot Cancer Center, Rochester,  New York,  14642,  United States

      Maimonides Medical Center, Brooklyn,  New York,  11219,  United States

      Memorial Sloan-Kettering Cancer Center, New York,  New York,  10021,  United States

      Mount Sinai School of Medicine, New York,  New York,  10029,  United States

      New York Medical College, Valhalla,  New York,  10595,  United States

      New York Presbyterian Hospital - Cornell Campus, New York,  New York,  10021-4885,  United States

      North Shore University Hospital, Manhasset,  New York,  11030,  United States

      Roswell Park Cancer Institute, Buffalo,  New York,  14263-0001,  United States

      Schneider Children's Hospital, New Hyde Park,  New York,  11042,  United States

      State University of New York - Upstate Medical University, Syracuse,  New York,  13210,  United States

      State University of New York Health Science Center at Brooklyn College of Medicine, Brooklyn,  New York,  11203,  United States

      State University of New York Health Sciences Center - Stony Brook, Stony Brook,  New York,  11790-7775,  United States

North Carolina
      Carolinas Medical Center, Charlotte,  North Carolina,  28232-2861,  United States

      Comprehensive Cancer Center at Wake Forest University, Winston Salem,  North Carolina,  27157-1081,  United States

      Duke Comprehensive Cancer Center, Durham,  North Carolina,  27710,  United States

      East Carolina University School of Medicine, Greenville,  North Carolina,  27858-4354,  United States

      Lineberger Comprehensive Cancer Center, UNC, Chapel Hill,  North Carolina,  27599-7295,  United States

      Mission Saint Joseph's Health System, Asheville,  North Carolina,  28801,  United States

      Presbyterian Healthcare, Charlotte,  North Carolina,  28233-3549,  United States

North Dakota
      Dakota Cancer Institute, Fargo,  North Dakota,  58103-4940,  United States

Ohio
      Children's Hospital Medical Center - Cincinnati, Cincinnati,  Ohio,  45229-3039,  United States

      Children's Hospital Medical Center of Akron, Akron,  Ohio,  44308,  United States

      Children's Hospital of Columbus, Columbus,  Ohio,  43205-2696,  United States

      Children's Medical Center - Dayton, Dayton,  Ohio,  45404,  United States

      Cleveland Clinic Taussig Cancer Center, Cleveland,  Ohio,  44195,  United States

      Forum Health-Tod Childrens Hospital, Youngstown,  Ohio,  44501,  United States

      Ireland Cancer Center, Cleveland,  Ohio,  44106-5065,  United States

      St. Vincent Mercy Medical Center, Toledo,  Ohio,  43608,  United States

      Toledo Children's Hospital, Toledo,  Ohio,  43601,  United States

Oklahoma
      CCOP - Oklahoma, Tulsa,  Oklahoma,  74136,  United States

      Children's Hospital of Oklahoma, Oklahoma City,  Oklahoma,  73104,  United States

      Natalie Warren Bryant Cancer Center, Tulsa,  Oklahoma,  74136,  United States

Oregon
      Doernbecher Children's Hospital, Portland,  Oregon,  97201-3098,  United States

      Legacy Emanuel Hospital and Health Center, Portland,  Oregon,  97227,  United States

Pennsylvania
      Children's Hospital of Philadelphia, Philadelphia,  Pennsylvania,  19104,  United States

      Children's Hospital of Pittsburgh, Pittsburgh,  Pennsylvania,  15213,  United States

      Geisinger Medical Center, Danville,  Pennsylvania,  17822-1320,  United States

      Milton S. Hershey Medical Center, Hershey,  Pennsylvania,  17033-0850,  United States

      St. Christopher's Hospital for Children, Philadelphia,  Pennsylvania,  19134-1095,  United States

Rhode Island
      Rhode Island Hospital, Providence,  Rhode Island,  02818,  United States

South Carolina
      Children's Hospital of Greenville Hospital System, Greenville,  South Carolina,  29605,  United States

      Medical University of South Carolina, Charleston,  South Carolina,  29425-0721,  United States

      Palmetto Health South Carolina Cancer Center, Columbia,  South Carolina,  29203,  United States

South Dakota
      Avera Cancer Institute, Sioux Falls,  South Dakota,  57105-1080,  United States

      Sioux Valley Hospital, Sioux Falls,  South Dakota,  57117,  United States

Tennessee
      East Tennessee Children's Hospital, Knoxville,  Tennessee,  37901,  United States

      East Tennessee State University Cancer Center at JCMC, Johnson City,  Tennessee,  37604,  United States

      Saint Jude Children's Research Hospital, Memphis,  Tennessee,  38105-2794,  United States

      Vanderbilt-Ingram Cancer Center, Nashville,  Tennessee,  37232-6838,  United States

Texas
      Baylor College of Medicine, Houston,  Texas,  77030,  United States

      Children's Hospital of Austin, Austin,  Texas,  78701,  United States

      Cook Children's Medical Center - Fort Worth, Fort Worth,  Texas,  76104,  United States

      Covenant Children's Hospital, Lubbock,  Texas,  79410,  United States

      Medical City Dallas Hospital, Dallas,  Texas,  75230,  United States

      Methodist Health Care System, San Antonio,  Texas,  78229-3902,  United States

      San Antonio Military Pediatric Cancer and Blood Disorders Center, Lackland Air Force Base,  Texas,  78236-5300,  United States

      Scott and White Memorial Hospital, Temple,  Texas,  76508,  United States

      Simmons Cancer Center - Dallas, Dallas,  Texas,  75235-9154,  United States

      Texas Tech University Health Sciences Center School of Medicine, Amarillo,  Texas,  79106,  United States

      University of Texas - MD Anderson Cancer Center, Houston,  Texas,  77030-4009,  United States

      University of Texas Health Science Center at San Antonio, San Antonio,  Texas,  78207,  United States

      University of Texas Medical Branch, Galveston,  Texas,  77555-0361,  United States

Utah
      Huntsman Cancer Institute, Salt Lake City,  Utah,  84112,  United States

Vermont
      Vermont Cancer Center, Burlington,  Vermont,  05401-3498,  United States

Virginia
      Cancer Center at the University of Virginia, Charlottesville,  Virginia,  22908,  United States

      Carilion Medical Center for Children, Roanoke,  Virginia,  24013,  United States

      Children's Hospital of the King's Daughters, Norfolk,  Virginia,  23507,  United States

      Inova Fairfax Hospital, Falls Church,  Virginia,  22042-3300,  United States

      Massey Cancer Center, Richmond,  Virginia,  23298-0037,  United States

      Naval Medical Center, Portsmouth, Portsmouth,  Virginia,  23708-5100,  United States

Washington
      Children's Hospital and Regional Medical Center - Seattle, Seattle,  Washington,  98105,  United States

      Deaconess Medical Center, Spokane,  Washington,  99210-0248,  United States

      Fred Hutchinson Cancer Research Center, Seattle,  Washington,  98109-1024,  United States

      Group Health Cooperative, Seattle,  Washington,  98112,  United States

      Madigan Army Medical Center, Tacoma,  Washington,  98431-5000,  United States

      Mary Bridge Children's Health Center, Tacoma,  Washington,  98415-0299,  United States

West Virginia
      Cabell-Huntington Hospital, Inc, Huntington,  West Virginia,  25701,  United States

      West Virginia University - Charleston, Charleston,  West Virginia,  25302,  United States

      West Virginia University Hospitals, Morgantown,  West Virginia,  26506-9300,  United States

Wisconsin
      Bellin Memorial Hospital, Green Bay,  Wisconsin,  54301,  United States

      CCOP - St. Vincent Hospital Cancer Center, Green Bay, Green Bay,  Wisconsin,  54301,  United States

      Gundersen Lutheran Medical Center, La Crosse,  Wisconsin,  54601,  United States

      Marshfield Clinic, Marshfield,  Wisconsin,  54449-5772,  United States

      Midwest Children's Cancer Center, Milwaukee,  Wisconsin,  53226,  United States

      St. Vincent Hospital, Green Bay,  Wisconsin,  54307-9070,  United States

      University of Wisconsin Hospital and Clinics, Madison,  Wisconsin,  53792-0001,  United States

Australia, New South Wales
      Children's Hospital at Westmead, Westmead,  New South Wales,  2145,  Australia

      Sydney Children's Hospital, Randwick,  New South Wales,  2031,  Australia

Australia, Queensland
      Royal Children's Hospital, Brisbane,  Queensland,  4029,  Australia

Australia, South Australia
      Women's and Children's Hospital, North Adelaide,  South Australia,  5006,  Australia

Australia, Victoria
      Royal Children's Hospital, Parkville,  Victoria,  3052,  Australia

Australia, Western Australia
      Princess Margaret Hospital for Children, Perth,  Western Australia,  6001,  Australia

Canada, Alberta
      Alberta Children's Hospital, Calgary,  Alberta,  T2T 5C7,  Canada

      Cross Cancer Institute, Edmonton,  Alberta,  T6G 1Z2,  Canada

Canada, British Columbia
      British Columbia Children's Hospital, Vancouver,  British Columbia,  V6H 3V4,  Canada

Canada, Manitoba
      CancerCare Manitoba, Winnipeg,  Manitoba,  R3E 0V9,  Canada

Canada, Newfoundland and Labrador
      Janeway Children's Health and Rehabilitation Centre, St. John's,  Newfoundland and Labrador,  A1B 3V6,  Canada

Canada, Nova Scotia
      IWK Health Centre, Halifax,  Nova Scotia,  B3J 3G9,  Canada

Canada, Ontario
      Children's Hospital of Eastern Ontario, Ottawa,  Ontario,  K1H 8L1,  Canada

      Children's Hospital of Western Ontario, London,  Ontario,  N6C 2V5,  Canada

      Children's Hospital, Hamilton,  Ontario,  L8N 3Z5,  Canada

      Hospital for Sick Children, Toronto,  Ontario,  M5G 1X8,  Canada

Canada, Quebec
      Centre Hospitalier de L'Universite Laval, Sainte-Foy,  Quebec,  GIV 4G2,  Canada

      Hopital Sainte Justine, Montreal,  Quebec,  H3T 1C5,  Canada

      Laval University Medical Center, Sainte-Foy,  Quebec,  G1V 4G2,  Canada

      McGill University Health Center - Montreal Children's Hospital, Montreal,  Quebec,  H3H 1P3,  Canada

Canada, Saskatchewan
      Allan Blair Cancer Centre, Regina,  Saskatchewan,  S4T 7T1,  Canada

      Saskatoon Cancer Centre, Saskatoon,  Saskatchewan,  S7N 4H4,  Canada

Netherlands
      Academisch Ziekenhuis Groningen, Groningen,  9700 RB,  Netherlands

New Zealand
      Starship Children's Hospital, Auckland,  New Zealand

Puerto Rico
      San Jorge Childrens Hospital, Santurce,  00912,  Puerto Rico

      University of Puerto Rico School of Medicine Medical Sciences Campus, San Juan,  00936-5067,  Puerto Rico

Switzerland
      Swiss Pediatric Oncology Group Bern, Bern,  CH 3010,  Switzerland

      Swiss Pediatric Oncology Group Geneva, Geneva,  CH 1211,  Switzerland

      Swiss Pediatric Oncology Group Lausanne, Lausanne,  CH 1011,  Switzerland

Study chairs or principal investigators

Richard E. Harris, MD,  Study Chair,  Children's Hospital Medical Center - Cincinnati   

More Information

Clinical trial summary from the National Cancer Institute's PDQ® database

Study ID Numbers:  CDR0000065390; COG-A5962; CCG-A5962; POG-A5962; CCG-5962
Record last reviewed:  April 2003
Last Updated:  October 13, 2004
Record first received:  November 1, 1999
ClinicalTrials.gov Identifier:  NCT00002941
Health Authority: Unspecified
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005

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