Sepsis Treatment and Symptoms trials Blood Poisoning; Septic Shock; Septicemia
Sepsis (in Greek Σήψις, putrefaction) is a serious medical condition, resulting from the immune response to a severe infection. Septicemia is sepsis of the bloodstream caused by bacteremia, which is the presence of bacteria in the bloodstream. The term septicemia is also used to refer to sepsis in general. Symptoms The immunological response that causes sepsis is a systemic inflammatory response causing widespread activation of inflammation and coagulation pathways. This may progre ...
Wikipedia - [full article]
Sepsis Clinical Trials
- A Safety and Efficacy Study of Intravenous E5564 in Patients with Severe Sepsis
ClinicalTrials.gov Identifier: NCT00046072 - Completed
Sepsis; Shock, Septic; Sepsis Syndrome; Septicemia; Infection
- Multicenter, Double-Blind, Placebo-Controlled Study To Evaluate Efficacy & Safety Of TAK-242 In Adults With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00143611 - Completed
Sepsis; Shock, Septic;; Sepsis Syndrome; Respiratory Insufficiency
- The Utility of Ischemia Modified Albumin (IMA) in Sepsis
ClinicalTrials.gov Identifier: NCT00448968 - Completed
Sepsis; Severe Sepsis; Systemic Inflammatory Response Syndrome; Sepsis Syndrome
- Phase I Study of Vasoactive Intestinal Peptide in Patients with Acute Respiratory Distress Syndrome and Sepsis
ClinicalTrials.gov Identifier: NCT00004494 - Recruiting
Sepsis; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Adult
- Unfractioned Heparin for Treatment of Sepsis
ClinicalTrials.gov Identifier: NCT00100308 - Recruiting
Sepsis; Bacterial Infections
- Prevention of Perinatal Sepsis (PoPS). Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn.
ClinicalTrials.gov Identifier: NCT00136370 - Recruiting
Infant, Newborn, Diseases; Sepsis; Puerperal Infection
- Observational Study of Sepsis and Pneumonia to Develop Diagnostic Tests
ClinicalTrials.gov Identifier: NCT00258869 - Recruiting
Sepsis; Septicemia; Sepsis Syndrome; Shock, Septic; Pneumonia
- BaSES Trial: Basel Starch Evaluation in Sepsis
ClinicalTrials.gov Identifier: NCT00273728 - Recruiting
Sepsis; Severe Sepsis; Septic Shock
- The Effects of EPA, GLA and Antioxidants in the Treatment of Sepsis
ClinicalTrials.gov Identifier: NCT00329680 - Recruiting
Sepsis; Severe Sepsis; Septic Shock
- Assessment of pleconaril for treatment of enteroviral sepsis syndrome in neonates
ClinicalTrials.gov Identifier: NCT00031512 - Not yet recruiting
Sepsis
- GR270773 In The Treatment Of Suspected Or Confirmed Gram-negative Severe Sepsis In Adults
ClinicalTrials.gov Identifier: NCT00089986 - Completed
Sepsis; Septic Shock
- Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis
ClinicalTrials.gov Identifier: NCT00049764 - Completed
Sepsis
- A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients with Severe Sepsis
ClinicalTrials.gov Identifier: NCT00034476 - Completed
Sepsis
- Prophylactic Heparin during Xigris [Drotrecogin Alfa (Activated)] Treatment of High-Risk Severe Sepsis
ClinicalTrials.gov Identifier: NCT00049777 - Completed
Sepsis
- A Safety and Efficacy Study of Hospitalized Patients with Community-Acquired Pneumonia and Sepsis
ClinicalTrials.gov Identifier: NCT00042588 - Completed
Pneumonia; Sepsis
- The Study of Drotrecogin Alfa (Activated) in a Subpopulation of Adult Patients with Severe Sepsis
ClinicalTrials.gov Identifier: NCT00045760 - Completed
Sepsis
- Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants
ClinicalTrials.gov Identifier: NCT00005888 - Completed
Necrotizing Enterocolitis; Sepsis
- Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
ClinicalTrials.gov Identifier: NCT00113191 - Completed
Nosocomial Infections; Sepsis; Staphylococcal Infections; Candidemia
- Randomized Trial of Prophylactic Vs Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation
ClinicalTrials.gov Identifier: NCT00138112 - Completed
Streptococcal Sepsis; Hematopoietic Stem Cell Transplantation; Hematologic Malignancies
- Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)
ClinicalTrials.gov Identifier: NCT00135473 - Completed
Severe sepsis; Septic Shock
- A Study To Compare The Effects Of The Infusion Of A Sepsis Drug Between Healthy Adults And Adults With Damaged Livers
ClinicalTrials.gov Identifier: NCT00158769 - Completed
Sepsis Septic shock
- Effect of Hyperglycemia in PAI-1 Activity and the Relationship with Outcome in Severe Sepsis and Septic Shock
ClinicalTrials.gov Identifier: NCT00159952 - Completed
Severe sepsis; Septic Shock
- Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis
ClinicalTrials.gov Identifier: NCT00037687 - Terminated
Sepsis
- Effects of Endotoxin in Normal Human Volunteers
ClinicalTrials.gov Identifier: NCT00001303 - Active, not recruiting
Healthy; Lung Disease; Sepsis; Septic Shock
- Study of Inhaled Nitric Oxide for Preterm Infants
ClinicalTrials.gov Identifier: NCT00016523 - Active, not recruiting
Respiratory Distress Syndrome; Infant, Premature; Sepsis; Pneumonia; Hypertension, Pulmonary
- Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients.
ClinicalTrials.gov Identifier: NCT00318552 - Active, not recruiting
Sepsis
- Sepsis: Prognosis and Evaluation of Early Diagnosis and Intervention (SPEEDI Study)
ClinicalTrials.gov Identifier: NCT00389337 - Active, not recruiting
SIRS; Sepsis
- Prevention of Infection in Indian Neonates
ClinicalTrials.gov Identifier: NCT00098176 - Recruiting
Sepsis
- Chlorhexidine Vaginal and Infant Wash in Pakistan
ClinicalTrials.gov Identifier: NCT00121394 - Recruiting
Sepsis; Pregnancy
- A Randomized Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients
ClinicalTrials.gov Identifier: NCT00133978 - Recruiting
Critical Illness; Sepsis; Organ Failure; Hypopertfusion
- Time Course of Procalcitonin and C Reactive Protein in Septic Patients Under Treatment with Corticosteroids
ClinicalTrials.gov Identifier: NCT00141973 - Recruiting
Procalcitonin, Sepsis,Corticosteroids
- Procalcitonin-Guided Antimicrobial Discontinuation
ClinicalTrials.gov Identifier: NCT00250666 - Recruiting
Sepsis
- Cysteine Supplementation in Critically Ill Neonates
ClinicalTrials.gov Identifier: NCT00254176 - Recruiting
Sepsis; Bronchopulmonary Dysplasia; Necrotizing Enterocolitis; Retinopathy of Prematurity; Systemic Inflammatory Response Syndrome
- The Procalcitonin And Survival Study
ClinicalTrials.gov Identifier: NCT00271752 - Recruiting
Localized Infection; Sepsis and Complications; Organ Failure
- Near Infrared Spectroscopy (NIRS) in Severe Sepsis
ClinicalTrials.gov Identifier: NCT00167596 - Recruiting
Critical Illness; Severe Sepsis
- Regulation of Endocrine, Metabolic, Immune and Bioenergetic Responses in Sepsis
ClinicalTrials.gov Identifier: NCT00187824 - Recruiting
Sepsis; Critical Illness
- Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis
ClinicalTrials.gov Identifier: NCT00222222 - Recruiting
Inflammation, Sepsis, SIRS
- Effect of APC and Epo on the Inflammatory Response During Sepsis.
ClinicalTrials.gov Identifier: NCT00229034 - Recruiting
Sepsis; Systemic Inflammation
- ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00334828 - Recruiting
Severe Sepsis
- Protocol-Driven Hemodynamic Support for Patients With Septic Shock
ClinicalTrials.gov Identifier: NCT00335907 - Recruiting
Shock, Septic; Severe Sepsis; Sepsis
- Effect of Rosuvastatin in Abdominal Sepsis
ClinicalTrials.gov Identifier: NCT00357123 - Recruiting
Sepsis
- Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis
ClinicalTrials.gov Identifier: NCT00368381 - Recruiting
Sepsis; Adrenal Insufficiency
- Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation
ClinicalTrials.gov Identifier: NCT00372502 - Recruiting
Severe Sepsis; Septic Shock
- Evaluate Impact to Protein C Levels With Changing Dose/Duration of Drotrecogin Alfa (Activated) Administered to Severe Sepsis Patients
ClinicalTrials.gov Identifier: NCT00386425 - Recruiting
Severe Sepsis
- Pharmacokinetic of Ceftriaxone in Septic ICU Patients
ClinicalTrials.gov Identifier: NCT00449800 - Recruiting
Sepsis; Severe Sepsis; Septic Shock
- Statin for Immunomudulation in Sepsis
ClinicalTrials.gov Identifier: NCT00452608 - Recruiting
Sepsis
- Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00464204 - Recruiting
Sepsis
- Multi-Marker INDex for the Risk Assessment of Sepsis in the Emergency departmenT (MINDSET)
ClinicalTrials.gov Identifier: NCT00472628 - Recruiting
Sepsis
- Alterations of Immunologic Mediators During Severe Sepsis
ClinicalTrials.gov Identifier: NCT00484146 - Recruiting
Severe Sepsis
- Microcirculation Guided Therapy Versus “Standard Treatment†of Severe Sepsis
ClinicalTrials.gov Identifier: NCT00484133 - Recruiting
Severe Sepsis; Microcirculation
- Methylene Blue in Sepsis: A Randomized Controlled Trial
ClinicalTrials.gov Identifier: NCT00486174 - Recruiting
Sepsis
- Safety and Efficacy of ART-123 in Subjects With Sepsis and Disseminated Intravascular Coagulation
ClinicalTrials.gov Identifier: NCT00487656 - Recruiting
Sepsis; Disseminated Intravascular Coagulation
- Sepsis, Endothelial Function, and Lipids in Critically Ill Patients With Liver Failure (the SELLIFA Study)
ClinicalTrials.gov Identifier: NCT00488917 - Recruiting
Liver Diseases; Liver Cirrhosis; Sepsis; Critical Illness
- Polymyxin-B Protects From Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial
ClinicalTrials.gov Identifier: NCT00490477 - Recruiting
Gram-Negative Bacterial Infections; Sepsis
- The Effect of Nitroglycerine on Microcirculatory Abnormalities During Sepsis
ClinicalTrials.gov Identifier: NCT00493415 - Recruiting
Sepsis; Septic Shock
- Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock
ClinicalTrials.gov Identifier: NCT00534287 - Recruiting
Severe Sepsis; Septic Shock
- Cytokine Removal by CRRT in Pediatric Sepsis
ClinicalTrials.gov Identifier: NCT00537693 - Recruiting
Sepsis
- Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis
ClinicalTrials.gov Identifier: NCT00559130 - Recruiting
Acute Respiratory Distress Syndrome; Acute Lung Injury; Sepsis
- Muscle Atrophy in Sepsis
ClinicalTrials.gov Identifier: NCT00583206 - Recruiting
Atrophy; Sepsis; Weakness
- Protocolized Care for Early Septic Shock
ClinicalTrials.gov Identifier: NCT00510835 - Not yet recruiting
Sepsis; Severe Sepsis; Septic Shock
- A Study in Sepsis Patients With Renal Failure
ClinicalTrials.gov Identifier: NCT00511186 - Not yet recruiting
Sepsis; Bacterial Infections and Mycoses
- Statins for the Early Treatment of Sepsis
ClinicalTrials.gov Identifier: NCT00528580 - Not yet recruiting
Sepsis
- Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis
ClinicalTrials.gov Identifier: NCT00541827 - Not yet recruiting
Severe Sepsis; Septic Shock
- Benefit of SeptiFast Multiplex PCR in the Etiologic Diagnosis and Therapeutic Approach for Onco-Hematology Patients Presenting Sepsis
ClinicalTrials.gov Identifier: NCT00561639 - Not yet recruiting
Hematologic Diseases; Sepsis
- Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants
ClinicalTrials.gov Identifier: NCT00005775 - Completed
Sepsis; Infant, Premature, Diseases
- A Prospective, Randomized, Phase III Trial of FLAC (5-Fluorouracil, Leucovorin, Adriamycin, Cytoxan) Chemotherapy with GM-CSF (Granulocyte-Macrophage Colony-Stimulating Factor) Versus PIXY 321 in Advanced Breast Cancer
ClinicalTrials.gov Identifier: NCT00001338 - Completed
Breast Neoplasms; Fever; Hematologic Diseases; Neutropenia; Sepsis
- Safety and Efficacy of MBI 226 for the Prevention of Central Venous Catheter-related Bloodstream Infections
ClinicalTrials.gov Identifier: NCT00027248 - Completed
Sepsis; Bacteremia; Fungemia
- A Safety Evaluation of Xigris in Patients with Blood Cancer who Develop Severe Infection related to Bone Marrow Transplantation.
ClinicalTrials.gov Identifier: NCT00067730 - Completed
Sepsis; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Infection
- Skin Cleansing with Chlorhexidine to Decrease Hospital Acquired Infections.
ClinicalTrials.gov Identifier: NCT00130221 - Completed
Nosocomial Infection; Bacteremia; Sepsis; Pneumonia; Urinary Tract Infection; Clostridium Difficile
- Effect of Leukoreduced Blood Transfusions on Infection Following Trauma
ClinicalTrials.gov Identifier: NCT00135291 - Completed
Wounds and Injuries; Infection; Sepsis; Hemorrhage
- The Benefit of Adding Fish Oil to the Nutrition of Critically Ill Patients
ClinicalTrials.gov Identifier: NCT00142220 - Completed
Sepsis Syndrome
- Procalcitonin Increase Identifies Critically Ill Patients at High Risk of Mortality
ClinicalTrials.gov Identifier: NCT00144638 - Completed
Sepsis - to reduce mortality in the Intensive Care Unit
- Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shock
ClinicalTrials.gov Identifier: NCT00148278 - Completed
Septic Shock; Severe sepsis; Infections
- Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis
ClinicalTrials.gov Identifier: NCT00185783 - Completed
Sepsis; Relative Adrenal Insufficiency
- Reconstruction of Monocytic Immunocompetence by GM-CSF in Patients With Severe Sepsis and Septic Shock
ClinicalTrials.gov Identifier: NCT00252915 - Completed
Sepsis Immunoparalysis
- Super High-Flux - High Volume Dialysis in Sepsis-Induced Acute Renal Failure
ClinicalTrials.gov Identifier: NCT00333593 - Completed
Sepsis; Acute Renal Failure
- The Effects of HIV Protease Inhibitors in Severe Sepsis
ClinicalTrials.gov Identifier: NCT00346580 - Completed
Sepsis
- Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis
ClinicalTrials.gov Identifier: NCT00406198 - Completed
Bacteremia; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Pneumonia, Bacterial; Shock, Septic; Sepsis
- Bovine Intestinal Alkaline Phosphatase for the Treatment of Patients With Sepsis
ClinicalTrials.gov Identifier: NCT00430859 - Completed
Sepsis; Multiple Organ Dysfunction Syndrome
- The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death
ClinicalTrials.gov Identifier: NCT00568737 - Completed
Sepsis
- An Open Label Study of Severe Sepsis in Adults
ClinicalTrials.gov Identifier: NCT00568893 - Completed
Severe Sepsis
- A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-Negative Sepsis in Adult
ClinicalTrials.gov Identifier: NCT00563134 - Suspended
Gram-Negative Bacterial Infections; Sepsis
- Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants
ClinicalTrials.gov Identifier: NCT00189384 - Active, not recruiting
Bacterial Infection; Sepsis; Infant, Newborn
- Infection Surveillance in Intensive Care Patients
ClinicalTrials.gov Identifier: NCT00197847 - Active, not recruiting
Infection; Pneumonia; Sepsis; Cross Infection
- Low-Dose Endotoxemia and the Acute Phase Response
ClinicalTrials.gov Identifier: NCT00197899 - Active, not recruiting
Endotoxemia; Sepsis
- Cortisol Control of Human Inflammatory Responses to Endotoxin
ClinicalTrials.gov Identifier: NCT00396344 - Active, not recruiting
Sepsis
- A Non-Invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients.
ClinicalTrials.gov Identifier: NCT00398736 - Active, not recruiting
Severe Sepsis; Septic Shock
- Functional Genomic Influences on Disease Progression and Outcome in Sepsis Due to Pneumonia or Peritonitis
ClinicalTrials.gov Identifier: NCT00131196 - Recruiting
Pneumonia; Peritonitis
- Procalcitonin in Diagnosing Bacteremia in the Emergency Department
ClinicalTrials.gov Identifier: NCT00174122 - Recruiting
Sepsis; Fever
- Botswana Pediatric Respiratory Disease and Bloodstream Infection Study
ClinicalTrials.gov Identifier: NCT00197691 - Recruiting
HIV Infections; Respiratory Tract Diseases; Sepsis
- Pro-Calcitonin Levels Following Pediatric Cardiac Surgery
ClinicalTrials.gov Identifier: NCT00284570 - Recruiting
Congenital Heart Disease; Sepsis; Infection
- Genetic Variation and Immune Responses After Injury
ClinicalTrials.gov Identifier: NCT00294697 - Recruiting
Sepsis; Pneumonia; Trauma; Burn; Injury
- Thrombin Generation and Thromboelastography in Non-Overt DIC
ClinicalTrials.gov Identifier: NCT00299949 - Recruiting
Sepsis; Disseminated Intravascular Coagulation
- Probiotics for the Prevention of Premature Birth and Neonatal Related Morbidity
ClinicalTrials.gov Identifier: NCT00303082 - Recruiting
Bacterial Vaginosis; Premature Birth; Sepsis; Periventricular Leukomalacia; Bronchopulmonary Dysplasia
- Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients
ClinicalTrials.gov Identifier: NCT00304772 - Recruiting
Candidiasis; Sepsis
- Impact of Heart Rate Characteristics Monitoring in Neonates
ClinicalTrials.gov Identifier: NCT00307333 - Recruiting
Sepsis
- The AOT (Acridine Orange and Taurolidine) Trial
ClinicalTrials.gov Identifier: NCT00321165 - Recruiting
Parenteral Nutrition; Infection; Sepsis
- Therapeutic Zinc in Infant Bacterial Illness
ClinicalTrials.gov Identifier: NCT00347386 - Recruiting
Sepsis; Bacterial Infections; Pneumonia
- Skeletal Muscle Oxygenation in Critically Ill
ClinicalTrials.gov Identifier: NCT00384644 - Recruiting
Heart Failure; Sepsis; Septic Shock; Cardiogenic Shock
- The CRISIS Prevention Study
ClinicalTrials.gov Identifier: NCT00395161 - Recruiting
Sepsis
Resources
- Blood Culture (Nemours Foundation)
- Blood Cultures (American Association for Clinical Chemistry)