Clinical Trial: Treatment for Women with Post-Traumatic Stress Disorder Related to Childhood Abuse

This study is currently recruiting patients.

Sponsored by: National Institute of Mental Health (NIMH)
Information provided by: National Institute of Mental Health (NIMH)

Purpose

The purpose of this study is to compare the effectiveness of one- and two-component treatments in women with Post-Traumatic Stress Disorder (PTSD) related to childhood abuse.

Condition Treatment or Intervention
Post-Traumatic Stress Disorders
 Behavior: Psychotherapy treatment

MedlinePlus related topics:  Post-Traumatic Stress Disorder

Study Type: Interventional
Study Design: Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Efficacy Study

Official Title: Skills Training, Exposure, and Their Combination in Childhood Abuse PTSD

Further Study Details: 

Expected Total Enrollment:  144

Study start: April 2002

PTSD is a debilitating and often chronic anxiety disorder with serious psychiatric comorbidity. The most common trauma associated with PTSD among women is childhood abuse. PTSD related to childhood abuse may cause problems with emotion regulation and interpersonal functioning. This study will address three domains of PTSD related to childhood abuse: emotion management problems, interpersonal problems, and PTSD symptoms.

Participants in this study will be randomly assigned to 16 sessions of one of three treatments: Skills Training for Affective and Interpersonal Regulation (STAIR), which focuses on helping individuals strengthen and build skills in managing feelings and improving interpersonal relationships; Modified Prolonged Exposure (MPE), which focuses on developing narratives of abuse history and completing an "emotional processing" of the trauma in a safe environment; and a combination of STAIR and MPE. Dropout rates and adverse effects will be measured.

Eligibility

Ages Eligible for Study:  22 Years   -   65 Years,  Genders Eligible for Study:  Female

Criteria

Inclusion Criteria:

  • DSM-IV criteria for Post-Traumatic Stress Disorder related to childhood physical and/or sexual abuse by a care-giver
  • At least one clear memory of the abuse
  • Willing to have all assessments tape recorded and sessions video taped
  • Willing to maintain any concurrent treatments for the duration of the study

Exclusion Criteria:

  • Bipolar Disorder
  • Eating Disorder
  • Borderline Personality Disorder
  • Active substance abuse or dependence
  • Living with the abuser
  • Self mutilation
  • Pregnancy

Location and Contact Information

Stephanie Cherry, CSW      212-263-2474 

New York
      NYU Child Study Center Institute for Trauma and Stress, New York,  New York,  10016,  United States; Recruiting
Stephanie Cherry, CSW  212-263-2474    stephanie.cherry@med.nyu.edu 
Marylene Cloitre, PhD,  Principal Investigator

More Information

http://www.AboutOurKids.org

Study ID Numbers:  62347-01A2
Record last reviewed:  December 2004
Last Updated:  December 21, 2004
Record first received:  September 24, 2003
ClinicalTrials.gov Identifier:  NCT00069381
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005

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