Evaluation of Acetabular Perfusion After Ganz Osteotomy by Positron Emission Tomography - Article Degenerative Joint Disease; Osteoarthritis arthritis
Clinical Trial: Evaluation of Acetabular Perfusion After Ganz Osteotomy by Positron Emission Tomography
This study is currently recruiting patients.
|Osteoarthritis || Procedure: Periacetabular osteotomy |
MedlinePlus related topics: Osteoarthritis
Study Type: Interventional
Study Design: Treatment, Non-Randomized, Single Blind, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Secondary Outcomes: fluoride uptake
Expected Total Enrollment: 14
Study start: January 2004; Expected completion: July 2007
Last follow-up: July 2006; Data entry closure: August 2006
As a consequence of periacetabular osteotomy the blood flow in acetabulum is decreased. After periacetabular osteotomy has been performed there is fine contact between the osteotomised acetabulum and the rest of the pelvis and the potential for healing is good. However, it has not been investigated how much the blood flow in acetabulum is changed after surgery. The blood flow is considered to be vital for how the pelvis heals after surgery. Most likely, the blood flow is important in relation to which degree osteoarthritis can be prevented after periacetabular osteotomy.
It is possible to estimate the blood flow by Positron Emission Tomography of the dysplastic hip joint pre- and postoperatively. In this study the blood flow and fluoride uptake is quantified by Positron emission tomography based on measurements of O-15 water and F-18 fluoride.
- Patients with radiologically diagnosed hip dysplasia (CE-angle < 25°).
- Patients with osteoarthritis graded 0, 1 or 2 defined according to Tönnis’ classification. Patients with pain from hip
- Age > 18 years.
- Minimum 110° flexion in hip joint and closed growth zones in the pelvic.
- Informed consent.
- Patients with neurological diseases
- Patients with calvé-Legg-Perthes syndrome.
- Patients where an femoral intertrochanteric osteotomy is necessary.
- Patients with medical sequelae after earlier hip surgery.
- Females who are pregnant.
- Patients with metal implants.
Location and Contact Information
Kjeld Søballe, MD, Prof. 89497425 Ext. 45 OVL09@as.aaa.dk
Orthopaedic Center, Aarhus University Hospital, Aarhus, 8000, Denmark; Recruiting
Inger B Mechlenburg, MScience, Sub-Investigator
Kjeld Søballe, MD, Prof., Principal Investigator
Flemming Hermansen, MD, Sub-Investigator
Jørgen Baas, MD, Sub-Investigator
Kjeld Søballe, MD, Prof., Principal Investigator, Orthopaedic Center, Aarhus University Hospital, Aarhus, Denmark
Record last reviewed: July 2005
Last Updated: July 25, 2005
Record first received: July 12, 2005
ClinicalTrials.gov Identifier: NCT00119444
Health Authority: Denmark: The Danish National Committee on Biomedical Research Ethics
ClinicalTrials.gov processed this record on 2005-07-26