A headache is a condition of mild to severe pain in the head; sometimes upper back or neck pain may also be interpreted as a headache.

21-hydroxylase deficiency is a disorder of steroid metabolism (the buildup or breakdown of steroids). Steroids are types of lipids (fats) that include cholesterol, vitamin D, and many hormones. The 21-hydroxylase deficiency results in the inability of the body to produce cortisol and aldosterone (steroid hormones that affect metabolism and salt balance, respectively) from cholesterol. This condition is also known as congenital adrenal hyperplasia. When the precursors of these hormones build up ...