Scientists Unveil Piece Of HIV Protein That May Be Key To AIDS Vaccine Development

Sun, 18 Feb 2007 10:00 AM EST

... In a finding that could have profound implications for AIDS vaccine design, researchers led by a team at the NIAID have generated an atomic-level picture of a key portion of an HIV surface protein as it looks when bound to an infection-fighting antibody. Unlike much of the constantly mutating virus, this protein component is stable and -- more importantly, say the researchers -- appears vulnerable to attack from this specific antibody, known as b12, that can broadly neutralize HIV. ...