The prevalence of obesity in children is reaching epidemic proportions. Excess adiposity is more than just a cosmetic problem, having substantial metabolic consequences. Insulin resistance, hyperinsulinemia, impaired glucose tolerance, and frank diabetes are often seen in obese children. In this study the prevalence of impaired glucose (carbohydrate) tolerance in lean children with a family history of diabetes and obese children with acanthosis nigricans with or without a family history of diabetes mellitus will be studied.

Condition
Obesity Glucose Intolerance Diabetes Acanthosis Nigricans

Ages Eligible for Study:  8 Years   -   18 Years,  Genders Eligible for Study:  Both

Accepts Healthy Volunteers

Criteria

Inclusion Criteria:

• Obesity: BM +/- 95% for age general good health

Sonia Caprio, M.D.      1-203-785-4648 

Connecticut
      Yale University School of Medicine, Pediatric Endocrinology, New Haven,  Connecticut,  06520-8064,  United States; Recruiting

Study ID Numbers:  NCRR-M01RR06022-0029; M01RR06022
Record last reviewed:  December 2003
Last Updated:  October 13, 2004
Record first received:  January 18, 2000
ClinicalTrials.gov Identifier:  NCT00000112
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08