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Periodontal Care and Glycemic Control in Diabetes - Article


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Glycemic Impact Diet

 




Clinical Trial: Periodontal Care and Glycemic Control in Diabetes

This study has been completed.

Sponsors and Collaborators: Department of Veterans Affairs
Colgate-Periogard-Dentsply
Information provided by: Department of Veterans Affairs

Purpose

Diabetes is a prevalent and costly disease among users of VA care. Goals of diabetes care include the prevention and/or delay of complications via adequate glycemic control. Improvements in periodontal status may also improve diabetes control.

This project will determine the efficacy of a program of periodontal screening and therapy in improving the level of glycemic control in poorly controlled diabetics.

This study will provide new information on the efficacy of periodontal care as an adjunctive therapy for diabetes care. Our findings on AE emphasize the need to closely monitor subjects in any clinical trial. VA patients who receive doxycycline or CHX should be carefully informed and monitored for AE.

Condition Treatment or Intervention
Diabetes Mellitus
Poor glycemic control
Periodontal Disease
 Drug: Doxycycline HCI 10mg po for 2 weeks
 Procedure: Ultrasonic scaling with 0.12% chlorhexidine gluconate

MedlinePlus related topics:  Diabetes;   Gum Disease;   Metabolic Disorders

Study Type: Interventional
Study Design: Treatment, Randomized, Single Blind, Active Control, Factorial Assignment, Efficacy Study

Further Study Details: 

Expected Total Enrollment:  300

Study start: January 2000;  Study completion: September 2003

Eligibility

Genders Eligible for Study:  Both

Criteria

  • Patients must have diabetes mellitus, and
  • HbAlc > 9,
  • > 8 teeth, and
  • CPITN scores of 3 or 4 in, at least 2 sextants of the mouth, indicating moderate to high periodontal treatment need.

Location Information


Massachusetts
      VA New England Health Care System, Bedford,  Massachusetts,  01730,  United States

More Information

Study ID Numbers:  DII 99-206
Record last reviewed:  March 2005
Last Updated:  April 1, 2005
Record first received:  March 14, 2001
ClinicalTrials.gov Identifier:  NCT00012688
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 9, 2005


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November 27, 2009



Page Updated: June 20, 2006
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