Nucleoside Analogues Clinical Trials

• SNAP: Switching Nucleoside Analogues Protocol - Lipoatrophy and Mitochondrial Function
  ClinicalTrials.gov Identifier: NCT00225082 - Active, not recruiting
  HIV Infection
  
• Study to Evaluate the Replacement of Reverse Transcriptase Nucleoside/Nucleotide Inhibitors by Nevirapine in Patients on Triple Treatment With Analogues Only
  ClinicalTrials.gov Identifier: NCT00415090 - Completed
  HIV Infections
  
• Comparing a Nucleoside-Analogue-Sparing Regimen and a Protease-Inhibitor-Sparing Regimen in HIV Infected Patients.
  ClinicalTrials.gov Identifier: NCT00135460 - Active, not recruiting
  HIV-Associated Lipodystrophy Syndrome; HIV; Hypercholesterolemia
  
• Predictive Factors of Response to Somatostatin Analogues in Acromegalic Patients With Persistent Disease Following Surgery
  ClinicalTrials.gov Identifier: NCT00500227 - Recruiting
  Acromegaly
  
• Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analogues
  ClinicalTrials.gov Identifier: NCT00539526 - Recruiting
  Open Angle Glaucoma; Ocular Hypertension
  
• Insulin Analogues and Severe Hypoglycaemia
  ClinicalTrials.gov Identifier: NCT00346996 - Not yet recruiting
  Type 1 Diabetes
  
• Safety Study Of Nucleoside Analog For The Treatment of HIV Positive Patients Who Have Failed Multiple HAART Regimens
  ClinicalTrials.gov Identifier: NCT00129194 - Active, not recruiting
  HIV
  
• GH, IGF-I and Somatostatin Analogues in Hepatocellular Carcinoma
  ClinicalTrials.gov Identifier: NCT00495846 - Recruiting
  Advanced Hepatocellular Carcinoma
  
• TOTEM: Switch From Other Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to Once Daily Truvada
  ClinicalTrials.gov Identifier: NCT00323492 - Recruiting
  HIV Infections
  
• How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis
  ClinicalTrials.gov Identifier: NCT00528788 - Recruiting
  Hyperparathyroidism, Secondary; Kidney Failure, Chronic; Endothelial Cells; Vitamin D
  
• Adaptive Phase I HCV Study With Nucleoside Analogue, in Combination With Interferon and Ribavirin
  ClinicalTrials.gov Identifier: NCT00382798 - Recruiting
  Healthy Volunteers; Hepatitis C Virus
  
• AVX754 (a New Nucleoside Reverse Transcriptase Inhibitor [NRTI]) to Treat Drug-Resistant HIV
  ClinicalTrials.gov Identifier: NCT00126880 - Active, not recruiting
  HIV Infections
  
• Prevention of HIV1 Mother to Child Transmission Without Nucleoside Analogue Reverse Transcriptase Inhibitors in the Pre-Partum Phase. ANRS 135 Primeva
  ClinicalTrials.gov Identifier: NCT00424814 - Recruiting
  HIV Infections
  
• A Randomized, Double-Blind, Four-Arm Study Comparing Combination Nucleoside, Alternating Nucleoside, and Triple-Drug Therapy for the Treatment of Advanced HIV Disease (CD4 <= 50/mm3)
  ClinicalTrials.gov Identifier: NCT00000781 - Completed
  HIV Infections
  
• A Randomized Trial of the Efficacy and Safety of a Strategy of Starting with Nelfinavir Versus Ritonavir Added to Background Antiretroviral (AR) Nucleoside Therapy in HIV-Infected Individuals with CD4+ Cell Counts Less than or Equal to 200/mm3
  ClinicalTrials.gov Identifier: NCT00000859 - Active, not recruiting
  HIV Infections
  
• Phase III Open Label Atazanavir (BMS-232632) in Combination with Ritonavir or Saquinavir, and Lopinavir/Ritonavir, each with Tenofovir and a Nucleoside in Subjects with HIV
  ClinicalTrials.gov Identifier: NCT00035932 - Active, not recruiting
  HIV Infections
  
• Study To Evaluate Long Term Maintenance With TRIZIVIR After Boosted Protease Inhibitor (PI) Or Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) In HIV-1 Infected Adults
  ClinicalTrials.gov Identifier: NCT00449436 - Recruiting
  HIV Infections
  
• Safety and Effectiveness of the Drug DPC 083 in Combination with Nucleoside Analogue Reverse Transcriptase Inhibitors in HIV-1-Infected Patients Who Are Failing Treatment with Nonnucleoside Reverse Transcriptase Inhibitors
  ClinicalTrials.gov Identifier: NCT00007449 - Active, not recruiting
  HIV Infections
  
• Comparing the Effectiveness of a Triple Nucleoside Reverse Transcriptase Inhibitor Regimen Versus a Protease Inhibitor-Based Regimen In the Prevention of Mother-to-Child Transmission of HIV
  ClinicalTrials.gov Identifier: NCT00270296 - Recruiting
  HIV Infections
  
• Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
  ClinicalTrials.gov Identifier: NCT00119405 - Recruiting
  HIV Infections; Lipodystrophy; Metabolic Diseases; Nutrition Disorders
  
• Effectiveness of Nucleoside Supplementation and Substituting Tenofovir Disoproxil Fumarate for Other Drugs in Anti-HIV Regimens in Reversing Fat Loss in HIV Infected Adults
  ClinicalTrials.gov Identifier: NCT00119379 - Recruiting
  HIV Infections; Lipodystrophy; Metabolic Diseases; Nutrition Disorders
  
• Study on the Effect of Kaletra + Nevirapine as Maintenance Bitherapy Compared to a Triple Therapy Including Kaletra + Analogues in HIV Patients
  ClinicalTrials.gov Identifier: NCT00335686 - Completed
  HIV Infections
  
• Studies in Porphyria IV: Gonadotropin-Releasing Hormone (GnRH) Analogues for Prevention of Cyclic Attacks
  ClinicalTrials.gov Identifier: NCT00004330 - Completed
  Porphyria
  
• A Randomized Prospective Study Evaluating the Impact On Fat Distribution of NRTI-Sparing Regimens in Antiretroviral Experienced Patients with Lipoatrophy
  ClinicalTrials.gov Identifier: NCT00122655 - Terminated
  HIV Infections; HIV Lipodystrophy Syndrome
  
• Evaluation of the Occurrence of Lipoatrophy in HIV-1 Infected Naive Patients
  ClinicalTrials.gov Identifier: NCT00122668 - Terminated
  HIV Infections; HIV-Associated Lipodystrophy Syndrome
  
• Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy
  ClinicalTrials.gov Identifier: NCT00000831 - Completed
  HIV Infections
  
• A Comparison of Three Treatments for Advanced HIV Disease in Patients Who Have Received Nucleoside Therapy in the Past
  ClinicalTrials.gov Identifier: NCT00001029 - Completed
  HIV Infections
  
• Monotherapy Versus Placebo Over 7 Days-Non-Nucleoside Reverse Transcriptase Inhibitor-experienced HIV1 Infected Adults
  ClinicalTrials.gov Identifier: NCT00090077 - Completed
  HIV Infections
  
• Randomized, Double-Blind Study Comparing Racivir and Lamivudine in Treatment-Experienced HIV Subjects.
  ClinicalTrials.gov Identifier: NCT00121979 - Completed
  HIV
  
• A Comparison of Two Dose Levels of Indinavir Combined with Two Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs) in HIV-Infected Patients
  ClinicalTrials.gov Identifier: NCT00002406 - Completed
  HIV Infections
  
• Safety and Effectiveness of Giving Two Nucleoside Reverse Transcriptase Inhibitors Alone or in Combination with 141W94 to HIV-Infected Children Who Have Never Received Protease Inhibitors
  ClinicalTrials.gov Identifier: NCT00002193 - Completed
  HIV Infections
  
• A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive
  ClinicalTrials.gov Identifier: NCT00002215 - Completed
  HIV Infections
  
• A Study to Evaluate the Safety and Effectiveness of a New Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), (+)-Calanolide A, in HIV-Positive Patients Who Have Never Received Anti-HIV Treatment
  ClinicalTrials.gov Identifier: NCT00002243 - Completed
  HIV Infections
  
• A Study of Capravirine Plus VIRACEPT Plus Two Nucleoside Reverse Transcriptase Inhibitors in HIV-Infected Patients Who Failed Previous Anti-HIV Treatments
  ClinicalTrials.gov Identifier: NCT00006211 - Completed
  HIV Infections
  
• A Randomized, Double-Blind Phase II/III Trial of Monotherapy vs. Combination Therapy With Nucleoside Analogs in HIV-Infected Persons With CD4 Cells of 200-500/mm3
  ClinicalTrials.gov Identifier: NCT00000625 - Completed
  HIV Infections
  
• A Study of Two Different Doses of ABT-378/Ritonavir in HIV-Infected Patients Who Have Taken Protease Inhibitors and Non-Nucleoside Reverse Transcriptase Inhibitors
  ClinicalTrials.gov Identifier: NCT00038636 - Completed
  HIV Infections
  
• Combination Treatment Using Capravirine (AG1549), Nelfinavir, and Two Nucleoside Reverse Transcriptase Inhibitors in HIV Patients Who Failed Initial Combination Therapy
  ClinicalTrials.gov Identifier: NCT00004985 - Completed
  HIV Infections
  
• A Pilot Study of Atazanavir/Ritonavir/Efavirenz as a Nucleoside Sparing Regimen.
  ClinicalTrials.gov Identifier: NCT00135343 - Completed
  HIV/AIDS
  
• Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination with Nucleoside Analogs: A Rollover Study for ACTG 320
  ClinicalTrials.gov Identifier: NCT00000885 - Completed
  HIV Infections
  
• A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease Inhibitors
  ClinicalTrials.gov Identifier: NCT00002235 - Completed
  HIV Infections
  
• A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies with Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (R
  ClinicalTrials.gov Identifier: NCT00002184 - Completed
  HIV Infections
  
• A Phase I and Pharmacokinetic Study of Clofarabine in Adult Patients with Advanced Solid Tumors
  ClinicalTrials.gov Identifier: NCT00125840 - Completed
  Pediatric ALL and AML; Adult ALL and AML and MDS; Solid Tumors
  
• Study of Oral Clofarabine Administered Daily for 5 Days in Adult Patients With Refractory Solid Tumors
  ClinicalTrials.gov Identifier: NCT00125827 - Completed
  Lymphoblastic Leukemia, Acute; Leukemia, Myelogenous, Acute; Myelodysplastic Syndromes; Tumors
  
• A Study to Test the Safety and Effectiveness of Dexelvucitabine, an Investigational Nucleoside Reverse Transcriptase Inhibitor (NRTI), to Lamivudine, an Approved NRTI, in HIV Treatment-Experienced Patients Who Are Resistant to Protease Inhibitors, NRTIs a
  ClinicalTrials.gov Identifier: NCT00300573 - Terminated
  HIV Infections; Human Immunodeficiency Virus
  
• A 48 week study comparing treatment with saquinavir + lopinavir/ritonavir in combination with enfuvirtide HAART versus saquinavir + lopinavir/ritonavir + other nucleoside combinations to see the efficacy of these treatments in patients infected with HIV-1
  ClinicalTrials.gov Identifier: NCT00100984 - Terminated
  HIV