This study will determine whether certain blood pressure medications will slow cyst growth or keep kidneys functioning longer in patients with autosomal dominant polycystic kidney disease (ADPKD). The study will take place at several sites in the United States. The start date of the study has not yet been determined.

Condition	Treatment or Intervention
Kidney, Polycystic Kidney, Polycystic, Autosomal Dominant	Drug: anti-hypertensive medications

Ages Eligible for Study:  15 Years   -   65 Years,  Genders Eligible for Study:  Both

Criteria

• Previous diagnosis of autosomal dominant polycystic kidney disease by abdominal imaging
• Previous diagnosis of high blood pressure or current blood pressures above 130/80 mm Hg

Colorado
      University of Colorado Health Sciences Center, Denver,  Colorado,  80262,  United States
Georgia
      Emory University, Atlanta,  Georgia,  United States
Kansas
      Kansas University Medical Center, Kansas City,  Kansas,  United States
Massachusetts
      Tufts - New England Medical Center, Boston,  Massachusetts,  United States
      Beth Israel Deaconess Medical Center, Boston,  Massachusetts,  United States
Minnesota
      Mayo Clinic, Rochester,  Minnesota,  United States
Ohio
      Cleveland Clinic Foundation, Cleveland,  Ohio,  United States

Study ID Numbers:  ADPKD
Record last reviewed:  November 2004
Last Updated:  November 17, 2004
Record first received:  September 3, 2003
ClinicalTrials.gov Identifier:  NCT00067977
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08