Gait disorders and falls are frequent in patients with parkinsonian syndromes. In patients with Parkinson''''s disease (PD), these signs occured later during the course of the disease in comparison to patients with others degenerative parkinsonian disorders. The pathophysiology of these symptoms are still not fully understood. Gait initiation challenges the balance control system as the body moves from an upright stable static posture to a continuously unstable gait. The aim of this study is to analyse gait initiation process in patients with parkinsonian disorders.

Condition	Intervention
Gait initiation Parkinson''''s Disease Parkinsonian Syndrome Adults	Device: Force platform and electromyography

Further Study Details: 

Primary Outcomes: Biomechanical gait initiation parameters
Expected Total Enrollment:  110

Ages Eligible for Study:  18 Years   -   85 Years,  Genders Eligible for Study:  Both

Accepts Healthy Volunteers

Criteria

Inclusion Criteria:

• Patients able to walk without assistance
• Patients with Parkinson''''s disease or others degenerative parkinsonian syndromes (PSP, MSA, CBD..)

Exclusion Criteria:

• Others parkinsonian syndromes
• Dementia
• Neuroleptic treatment

Please refer to this study by ClinicalTrials.gov identifier  NCT00139321

Marie-Laure Welter, MD      33-142161950    marie-laure.welter@psl.aphp.fr

France
      Centre d''''Investigation Clinique-HÔPITAL PITIÉ-SALPETRIERE, Paris,  75013,  France; Recruiting

Study chairs or principal investigators

Yves AGID, MD, PhD,  Study Director,  CIC-Pitié-Salpêtrière   

Study ID Numbers:  RBM0260
Last Updated:  August 30, 2005
Record first received:  August 30, 2005
ClinicalTrials.gov Identifier:  NCT00139321
Health Authority: France: Ministry of Health
ClinicalTrials.gov processed this record on 2005-09-06