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Mood Disorder |
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Clinical Trial: Neuropsychological Evaluation of Psychiatric and Neurological Patients
This study is currently recruiting patients.
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Purpose
This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning, language, memory, motor functions, orientation, personality, selected sensory and perceptual functions, vigilance (alertness), and visual-spatial functions. Children and adult patient will receive different test batteries.
The goals of this research study are to;
1. Create descriptions based on the performance of each patient on the test batteries. Then use this information to relate patient behavior to their neurophysiological, neuroradiological, and biochemical descriptions.
2. Define subgroups of patients based on their neurobehavior in order to decrease the variability of psychiatric diagnoses, treatments, and prognoses.
| Condition |
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| Anxiety Disorder Head Injury Mood Disorder Schizophrenia Seizures |
MedlinePlus related topics: Anxiety; Head and Brain Injuries; Mental Health; Schizophrenia; Seizures
Study Type: Observational
Study Design: Natural History
Expected Total Enrollment: 4300
Study start: October 18, 1983
Neuropsychological tests are used to provide an assessment of cognitive functions in patients with idiopathic generralized epileptic (IGE) disorders and their first-degree relatives. The battery comprises tests designed to tap attention, memory, selected sensory and perceptual functions, vigilance, and visual-spatial functions. Modified batteries have been developed for the assessment of children ages 5-8, and children ages 8-16. The data provided by these batteries are compared with genetic profiles of the same participants that have been ascertained from blood samples analyzed by colleagues at the Mount Sinai School of Medicine/Columbia University in New York City.
Eligibility
Genders Eligible for Study: Both
Accepts Healthy Volunteers
Criteria
Patients.
Normal volunteers.
EXCLUSION CRITERIA:
Subjects over 95 years of age.
Subjects with a history of alcohol or drug abuse, psychopathology, or central nervous system pathology, other than that which defines group membership, may be excluded.
Location and Contact Information
Maryland
National Institute of Mental Health (NIMH), 9000 Rockville Pike, Bethesda, Maryland, 20892, United States; Recruiting
TTY 1-866-411-1010
More Information
Detailed Web Page
Publications
Mirsky AF, Anthony BJ, Duncan CC, Ahearn MB, Kellam SG. Analysis of the elements of attention: a neuropsychological approach. Neuropsychol Rev. 1991 Jun;2(2):109-45. Review.
Mirsky AF, Yardley SL, Jones BP, Walsh D, Kendler KS. Analysis of the attention deficit in schizophrenia: a study of patients and their relatives in Ireland. J Psychiatr Res. 1995 Jan-Feb;29(1):23-42.
Johnstone EC, Owens DG, Bydder GM, Colter N, Crow TJ, Frith CD. The spectrum of structural brain changes in schizophrenia: age of onset as a predictor of cognitive and clinical impairments and their cerebral correlates. Psychol Med. 1989 Feb;19(1):91-103.
Record last reviewed: February 16, 2005
Last Updated: March 18, 2005
Record first received: November 3, 1999
ClinicalTrials.gov Identifier: NCT00001192
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 9, 2005
Resources
- Mood Disorder (Cleveland Clinic)
- Mood Disorders Intensive Outpatient Program (Cleveland Clinic)
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