Randomised trial comparing Cognitive Therapy and Supportive Therapy administered along one year in borderline personality disorder. The follow-up is one year after treatments end.

The therapists were the same in the two groups Patients received one session a week during six months and one session every two weeks during the next six months • Cognitive Therapy • Structured session • Conceptualization of the case with the patient • Cognitive methods • Guided discovery of the schemas • Work on life-scenarios • From scenarios to schemas • Empathic confrontation to the schemas • Building new schemas (Core belief work-sheet) • Affective methods: role playing • Interpersonal methods: counter transference issues • Behavioral experiment • Problem solving • Consolidation methods • Patients and therapists had manuals

• Supportive Therapy • Therapist: active listening (face to face) • Empathy • Unconditional positive regard • Reformulation and clarification • Reflection of the patient’s feelings • Reassurance • Therapist emphasizes the importance to ventilate problems • 8) Therapist answers some factual questions • 9) Therapist politely ignore or refuse requests for advice and directive attitudes • 10) Therapist demonstrates warmth and genuineness • Patients and therapists had manuals

Condition	Intervention
Borderline Personality Disorder	Behavior: Cognitive Therapy  Behavior: Supportive Therapy

Further Study Details: 

Primary Outcomes: CGI: Improvement (1-7) : score 3 ( a little better) associated with a; hopelessness scale score < 8 (this means that the suicide risk is low)
Secondary Outcomes:  CGI severity and improvement;  Hamilton depression;  Beck Depression Inventory;  Hopelessness;  Young: Schema Questionnaire II;  SCID II PQ;  MMPI (minimult);  Eysenck : impulsivity scale;  Checklist : impulsive risky behaviors;  Quality of life;  Handicap (Sheehan); Time : Pre test, six months, post test and one year post treatment follow-up;  Therapeutic relationship evaluation scale (patients and therapists) :
Expected Total Enrollment:  70

Ages Eligible for Study:  18 Years   -   65 Years,  Genders Eligible for Study:  Both

Criteria

Inclusion Criteria:

DSM-4 DIBR >=8 (Diagnostic inventory for borderline- revised)

Exclusion Criteria:

-

France
      Hopital Pierre Wertheimer, Bron,  69677,  France

Study chairs or principal investigators

Jean COTTRAUX, MD,  Principal Investigator,  Hospices Civils de Lyon   

Study ID Numbers:  2000.230
Last Updated:  August 23, 2005
Record first received:  August 18, 2005
ClinicalTrials.gov Identifier:  NCT00131781
Health Authority: France: Ministry of Health
ClinicalTrials.gov processed this record on 2005-09-13