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Antisocial Behavior: Passing From Parent to Child to Grandchild - Article


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Narcissistic personality disorder

 




Clinical Trial: Antisocial Behavior: Passing From Parent to Child to Grandchild

This study is currently recruiting patients.

Sponsored by: National Institute of Child Health and Human Development (NICHD)
Information provided by: National Institute of Child Health and Human Development (NICHD)

Purpose

Antisocial behavior often occurs in different generations within the same family. However, it is not known what factors contribute to this passing of antisocial behavior from parent to child to grandchild. This study is part of a project evaluating antisocial behavior in families; it focuses on the passage of such behavior from one generation to the next.

Condition
Dyssocial Behavior
Antisocial Personality Disorder

MedlinePlus related topics:  Personality Disorders

Study Type: Observational
Study Design: Natural History, Longitudinal, Defined Population, Prospective Study

Official Title: Intergenerational Transmission of Antisocial Behavior

Further Study Details: 

While it is well-known that antisocial behavior runs in families, little is known about the specific mechanisms by which it is transmitted from one generation to the next. This prospective study will examine biological influences on transgenerational continuity and change, and how biology interacts with social factors in modulating the transmission of antisocial behavior. The study is unique in that it includes both mothers and fathers, focuses on early mechanisms, and addresses female as well as male antisocial behavior.

This study is part of the continuing Mauritius Child Health Project. The project began by testing 1,795 children age 3 years old on psychophysiological, behavioral, nutritional, and cognitive measures. Both male and female children were tested. Their parents were also assessed for psychosocial influences. One hundred children then participated in a nutritional, exercise, and educational enrichment intervention from ages 3 to 5 years old. The intervention has been shown to increase physiological arousal and attention at age 11 years and to reduce conduct disorder at age 17 years.

These 3-year-old children are now 30-year-old adults. This study will retest these adults on psychophysiological, psychosocial, cognitive, behavioral, parenting, and antisocial behavior measures. Their previously untested spouses will also be assessed. Finally, many of these adults now have 3-year-old children of their own; these children will be evaluated as well. Measures of life stress, daily hassles, family conflict, mental illness, and criminal behavior will be assessed. Data from the enrichment cohort will be evaluated to determine if the intervention disrupted the intergenerational transmission of antisocial behavior from the second to third generations.

Eligibility

Ages Eligible for Study:  36 Months   -   48 Months,  Genders Eligible for Study:  Both

Accepts Healthy Volunteers

Criteria

Inclusion Criteria

  • Child of a participant tested in previous Mauritius Child Health Project studies

Location and Contact Information


Mauritius
      Joint Child Health Project, Quatre Bornes,  Mauritius; Recruiting
Kjetil Mellingen  230-453-9123 

Study chairs or principal investigators

Adrian Raine,  Principal Investigator,  University of Southern California   

More Information

Study ID Numbers:  1R01HD42259-1
Record last reviewed:  May 2003
Last Updated:  October 13, 2004
Record first received:  May 13, 2003
ClinicalTrials.gov Identifier:  NCT00060788
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08


Source: ClinicalTrials.gov
Cache Date: April 8, 2005


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December 3, 2009



Page Updated: October 15, 2009
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