Dependence Clinical Trials

• LINK: Longer Intervention to Increase sKills
  ClinicalTrials.gov Identifier: NCT00265512 - Recruiting
  Alcohol Dependence; Drug Dependence
  
• Employment-Based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2
  ClinicalTrials.gov Identifier: NCT00249457 - Active, not recruiting
  Behavior Therapy; Cocaine Abuse; Cocaine Dependence; Contingency Management; Heroin Dependence; Methadone; Opioid Dependence
  
• The Maternal Lifestyle Study (MLS)
  ClinicalTrials.gov Identifier: NCT00059540 - Active, not recruiting
  Cocaine Abuse; Cocaine Dependence; Opiate Dependence
  
• Randomised Placebo-Controlled Trial of Modafinil for Methamphetamine Dependence
  ClinicalTrials.gov Identifier: NCT00123370 - Active, not recruiting
  Amphetamine Dependence
  
• Novel Pharmacotherapy for Dual Dependence
  ClinicalTrials.gov Identifier: NCT00448825 - Recruiting
  Alcohol Dependence; Cocaine Dependence
  
• Randomised Placebo-Controlled Trial of Modafinil for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00123383 - Active, not recruiting
  Cocaine Dependence
  
• Buprenorphine/Naloxone Versus Clonidine for Inpatient Opiate Detoxification - 1
  ClinicalTrials.gov Identifier: NCT00032955 - Active, not recruiting
  Heroin Dependence; Morphine Dependence; Substance Withdrawal Syndrome
  
• Buprenorphine/Naloxone Versus Clonidine for Outpatient Opiate Detoxification - 1
  ClinicalTrials.gov Identifier: NCT00032968 - Active, not recruiting
  Heroin Dependence; Morphine Dependence; Substance Withdrawal Syndrome
  
• Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical Dependence Treament: A Pilot Trial
  ClinicalTrials.gov Identifier: NCT00461890 - Recruiting
  Alcohol Dependence; Veterans
  
• Behavioral Naltrexone Therapy: A Novel Treatment for Heroin Dependence
  ClinicalTrials.gov Identifier: NCT00332228 - Active, not recruiting
  Opiate Dependence
  
• Memantine as a Supplement to Naltrexone in Treating Heroin Dependence
  ClinicalTrials.gov Identifier: NCT00476242 - Recruiting
  Opioid Dependence; Heroin Dependence
  
• A Randomized Control Trial Comparing Quetiapine to Risperidone in Bipolar Disorder With Stimulant Dependence
  ClinicalTrials.gov Identifier: NCT00227123 - Recruiting
  Bipolar Disorder; Cocaine Dependence; Amphetamine Dependence
  
• Free Treatment for Cocaine Dependence: A Placebo-Controlled Study of Mixed Amphetamine Salts (Adderall-XR) and Topiramate for the Treatment of Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00421603 - Recruiting
  Cocaine Dependence
  
• Combined Treatment for Cocaine-Alcohol Dependence - 1
  ClinicalTrials.gov Identifier: NCT00218569 - Active, not recruiting
  Alcohol Dependence; Cocaine Dependence
  
• Treatment of Nicotine Dependence and Acute Depression
  ClinicalTrials.gov Identifier: NCT00186446 - Active, not recruiting
  Major Depressive Disorder; Nicotine Dependence
  
• A Trial of Long-Acting Injectable Risperidone in the Treatment of Methamphetamine Dependence
  ClinicalTrials.gov Identifier: NCT00284206 - Active, not recruiting
  Methamphetamine Dependence
  
• Medication Development for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00223626 - Recruiting
  Cocaine Dependence
  
• Double Blind Study of Vigabatrin for the Treatment of Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00527683 - Active, not recruiting
  Cocaine Dependence
  
• Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00385801 - Active, not recruiting
  Cocaine Dependence
  
• Injectable Versus Oral Naltrexone Treatment of Alcohol Dependence In Serious Mental Illness (SMI)
  ClinicalTrials.gov Identifier: NCT00453804 - Active, not recruiting
  Bipolar Disorders; Schizophrenia; Schizoaffective Disorders; Alcohol Dependence
  
• Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1
  ClinicalTrials.gov Identifier: NCT00218660 - Active, not recruiting
  Alcoholism; Cocaine Abuse, Cocaine-Related Disorders; Cocaine Dependence
  
• Brief Introductory Therapy for Opioid Dependence
  ClinicalTrials.gov Identifier: NCT00406484 - Recruiting
  Opiate Dependence; HIV Infections
  
• Pharmacogenetics of Disulfiram for Cocaine - 2
  ClinicalTrials.gov Identifier: NCT00149630 - Recruiting
  Cocaine Dependence; Opioid Dependence
  
• Testing a Full Substitution Therapy Approach As Treatment of Tobacco Dependence
  ClinicalTrials.gov Identifier: NCT00390923 - Recruiting
  Smoking; Nicotine Dependence
  
• Stress, Distress Intolerance, and Drug Dependence
  ClinicalTrials.gov Identifier: NCT00430482 - Recruiting
  Substance Dependence
  
• Safety and Tolerability of Modafinil for Methamphetmaine Dependence
  ClinicalTrials.gov Identifier: NCT00569374 - Recruiting
  Methamphetamine Dependence
  
• Addiction Health Evaluation And Disease Management (AHEAD) Study
  ClinicalTrials.gov Identifier: NCT00278447 - Recruiting
  Alcohol Dependence; Alcoholism; Drug Dependence
  
• Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14
  ClinicalTrials.gov Identifier: NCT00015340 - Active, not recruiting
  Heroin Dependence; Substance-Related Disorders
  
• Propranolol and Amantadine for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00128349 - Active, not recruiting
  Cocaine Dependence
  
• Substance Abuse Pre-Treatment Screening Study
  ClinicalTrials.gov Identifier: NCT00439049 - Recruiting
  Cocaine Abuse; Cocaine Dependence; Opiate Dependence; Alcohol Dependence; Substance Abuse
  
• A Randomized, Double-Blind, Placebo-Controlled Add-On Trial Quetiapine in Patients With Bipolar and Alcohol Abuse/Dependence
  ClinicalTrials.gov Identifier: NCT00223249 - Active, not recruiting
  Bipolar Disorder; Alcohol Abuse/Dependence
  
• Atomoxetine for the Treatment of Cannabis Dependence
  ClinicalTrials.gov Identifier: NCT00167297 - Active, not recruiting
  Cannabis Dependence
  
• Will the Use of Baclofen Reduce Cocaine Use in Patients With Cocaine Dependence?
  ClinicalTrials.gov Identifier: NCT00431938 - Active, not recruiting
  Cocaine Dependence
  
• A Double-Blind Placebo-Controlled Trial of Citicoline Add-On Therapy in Patients With a History of Mania or Hypomania and Cocaine Abuse/Dependence
  ClinicalTrials.gov Identifier: NCT00223236 - Active, not recruiting
  Mania/Hypomania; Cocaine Abuse/Dependence
  
• Community-Based Modafinil Treatment of Women With Cocaine Dependence and HIV-High Risk Behavior
  ClinicalTrials.gov Identifier: NCT00368290 - Recruiting
  Cocaine Dependence
  
• A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00344565 - Recruiting
  Cocaine Dependence
  
• Study of Buprenorphine Maintenance Treatment for Opioid Dependence in Primary Care
  ClinicalTrials.gov Identifier: NCT00471042 - Recruiting
  Heroin Dependence; Opioid-Related Disorders; Substance Abuse, Intravenous
  
• Opioid Withdrawal Suppression with Tramadol - 1
  ClinicalTrials.gov Identifier: NCT00142896 - Active, not recruiting
  Opioid Dependence
  
• Brain Function in Response to Motivational Stimuli
  ClinicalTrials.gov Identifier: NCT00047866 - Recruiting
  Drug Dependence
  
• Study of Campral (Acamprosate) for Alcohol Dependence in a Family Medicine Clinic
  ClinicalTrials.gov Identifier: NCT00381043 - Recruiting
  Alcohol Dependence
  
• Neurocognitive Functioning Following The PROMETA® Treatment Protocol In Subjects With Alcohol Dependence
  ClinicalTrials.gov Identifier: NCT00570388 - Recruiting
  Alcohol Dependence
  
• Opiate Dependence: Combined Naltrexone/Behavior Therapy - 1
  ClinicalTrials.gov Identifier: NCT00238914 - Active, not recruiting
  Behavior Therapy; Naltrexone; Opioid Dependence
  
• Targeted Interventions for Weight-Concerned Smokers
  ClinicalTrials.gov Identifier: NCT00105482 - Recruiting
  Nicotine Dependence
  
• Assessment and Treatment of Caffeine Dependence
  ClinicalTrials.gov Identifier: NCT00338195 - Recruiting
  Self-Identified Problematic Caffeine Use; DSM-IV Substance Dependence as Applied to Caffeine
  
• Imaging the Neurobiology of a Behavioral Treatment for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00376558 - Recruiting
  Cocaine Dependence
  
• Pilot Trial of Acamprosate for the Treatment of Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00385268 - Recruiting
  Cocaine Dependence
  
• Safety and Efficacy of Probuphine in the Treatment of Opioid Dependence
  ClinicalTrials.gov Identifier: NCT00447564 - Recruiting
  Opioid Dependence
  
• Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With Schizophrenia
  ClinicalTrials.gov Identifier: NCT00407277 - Recruiting
  Smoking; Nicotine Dependence; Schizophrenia; Schizophreniform Disorders; Schizoaffective Disorder; Psychosis
  
• Prometa Pharmacotherapy for Methamphetamine Dependence
  ClinicalTrials.gov Identifier: NCT00260481 - Recruiting
  Drug Abuse; Drug Dependence
  
• Open-Label Depakote ER in Patients With Bipolar I or II Depression and Alcohol Abuse or Dependence
  ClinicalTrials.gov Identifier: NCT00204503 - Active, not recruiting
  Bipolar I or II Depression and Alcohol Abuse or Dependence
  
• Buprenorphine Maintenance vs. Detoxification in Prescription Opioid Dependence
  ClinicalTrials.gov Identifier: NCT00555425 - Not yet recruiting
  Opiate Dependence
  
• Topiramate for Alcohol and Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00167245 - Recruiting
  Alcoholism; Cocaine Dependence
  
• N-Acetyl Cysteine Plus Naltrexone in Methamphetamine Dependence
  ClinicalTrials.gov Identifier: NCT00332605 - Recruiting
  Methamphetamine Dependence
  
• Use of Donepezil for Treatment of Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00467389 - Recruiting
  Cocaine Abuse and Dependence
  
• Modafinil vs Placebo for the Treatment of Methamphetamine Dependence
  ClinicalTrials.gov Identifier: NCT00469508 - Recruiting
  Methamphetamine Dependence
  
• Functional Brain Imaging in Recreational Users of Ecstasy
  ClinicalTrials.gov Identifier: NCT00254306 - Recruiting
  Dependence on Ecstasy
  
• HEPMET-1: Evaluate the Feasibility, Mental Sideeffects and the Efficacy of Hepatitis C Treatment in a MMT Group.
  ClinicalTrials.gov Identifier: NCT00147784 - Recruiting
  Opiate Dependence; Hepatitis
  
• A Comparison of Adolescent Group Therapy and Transitional Family Therapy for Adolescent Alcohol and Drug Abusers
  ClinicalTrials.gov Identifier: NCT00484367 - Active, not recruiting
  Alcohol Abuse; Alcohol Dependence; Cannabis Abuse; Cannabis Dependence; Other Substance Abuse
  
• A Free Treatment Study for Cocaine Dependence Looking at the Effectiveness of Mirtazapine in Treating Cocaine Dependent Individuals Who Also Suffer From Depression
  ClinicalTrials.gov Identifier: NCT00249444 - Recruiting
  Cocaine Dependence; Depression
  
• Employment-Based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction - 1
  ClinicalTrials.gov Identifier: NCT00249470 - Active, not recruiting
  Cocaine; Cocaine Abuse; Contingency Management; HIV; HIV Risk Behaviors; Heroin; Heroin Dependence; Methadone; Opioid Dependence; Substance Abuse, Intravenous; Alcohol & Drug Use; Sexual Risk Behaviors
  
• Effectiveness of Gabapentin When Used With Naltrexone to Treat Alcohol Dependence Compared to Placebo and Naltrexone Alone
  ClinicalTrials.gov Identifier: NCT00183196 - Recruiting
  Alcohol Dependence
  
• The Safety and Efficacy of Eszopiclone in the Treatment of Insomnia in Patients With Alcohol Dependence
  ClinicalTrials.gov Identifier: NCT00580411 - Recruiting
  Insomnia; Alcohol Dependence
  
• Gabapentin Treatment of Alcohol Dependence
  ClinicalTrials.gov Identifier: NCT00391716 - Recruiting
  Alcoholism; Alcohol Abuse; Alcohol Dependence
  
• Effects of Sustained Release d-Amphetamine and Buprenorphine on Drug Seeking Behavior in Opioid and Cocaine Dependent Individuals Who Are Not Seeking Treatment
  ClinicalTrials.gov Identifier: NCT00429767 - Recruiting
  Heroin Dependence; Opioid-Related Disorders; Cocaine Abuse or Dependence
  
• Effectiveness of Memantine in Treating Heroin-Dependent Individuals - 1
  ClinicalTrials.gov Identifier: NCT00126711 - Recruiting
  Heroin Dependence
  
• Gabapentin Treatment of Cannabis Dependence
  ClinicalTrials.gov Identifier: NCT00395044 - Recruiting
  Cannabis Dependence
  
• Naltrexone for Bipolar Disorder and Alcohol Dependence
  ClinicalTrials.gov Identifier: NCT00223275 - Active, not recruiting
  Bipolar Disorder; Alcohol Dependence
  
• Use of Pharmacotherapy to Reduce Cue-Responsiveness in Smokers
  ClinicalTrials.gov Identifier: NCT00133757 - Completed
  Nicotine Dependence; Tobacco Dependence
  
• Reducing Sex-Related HIV Risk Behaviors in Patients Receiving Treatment for Opioid Dependence
  ClinicalTrials.gov Identifier: NCT00548275 - Recruiting
  Opiate Dependence; HIV Risk Behaviors; HIV Infections
  
• Lofexidine for Inpatient Opiate Detox
  ClinicalTrials.gov Identifier: NCT00235729 - Recruiting
  Opiate Dependence
  
• A Laboratory Model for Heroin Abuse Medications - 8
  ClinicalTrials.gov Identifier: NCT00000273 - Active, not recruiting
  Heroin Dependence; Opioid-Related Disorders; Substance-Related Disorders
  
• Place of Low-Dose Naltrexone in Opiate Detoxification - 1
  ClinicalTrials.gov Identifier: NCT00135759 - Active, not recruiting
  Heroin Dependence; Opioid-Related Disorders; Substance-Related Disorders
  
• Mecamylamine for the Treatment of Patients With Depression and Alcohol Dependence
  ClinicalTrials.gov Identifier: NCT00563797 - Recruiting
  Alcohol Dependence; Depression
  
• Nicotine Replacement Treatment for Pregnant Smokers
  ClinicalTrials.gov Identifier: NCT00064948 - Recruiting
  Nicotine Dependence; Pregnancy
  
• An Add-On Trial of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00223210 - Recruiting
  Bipolar Disorder; Cocaine Dependence
  
• Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00495183 - Not yet recruiting
  Cocaine Dependence
  
• Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
  ClinicalTrials.gov Identifier: NCT00579267 - Recruiting
  Major Depression; Mania; Anxiety Disorders; Psychotic Disorder; Alcohol Dependence; Drug Dependence; Eating Disorders; Suicidality; Dysthymia; ADHD; Tourettes Disorder; Conduct Disorder; Oppositional Defiant Disorder; Pervasive Developmental Disorder
  
• A Controlled Trial: Subjects Enrolled in the Study Receive Either NAC or Placebo. NAC is a N Acetyl Pro-Drug of the Naturally-Occurring Amino Acid Cystine. Subjects Enrolled in the Study Are Addicted to Cocaine - 1
  ClinicalTrials.gov Identifier: NCT00218491 - Recruiting
  Cocaine Dependence
  
• Randomized, Double-Blind, Placebo-Controlled Study of Mixed Amphetamine Salts (Adderall-XR) for the Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) and Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00553319 - Recruiting
  Adult Attention Deficit Hyperactivity Disorder; Cocaine Dependence
  
• Prazosin Alcohol Dependence IVR Study
  ClinicalTrials.gov Identifier: NCT00167687 - Active, not recruiting
  Alcoholism
  
• Emergency Department Telephone Quitline
  ClinicalTrials.gov Identifier: NCT00394420 - Active, not recruiting
  Tobacco Dependence
  
• Employment-Based Incentives to Motivate Naltrexone Ingestion and Drug Abstinence in the Treatment of Drug Addiction. - 1
  ClinicalTrials.gov Identifier: NCT00149669 - Not yet recruiting
  Behavior Therapy; Cocaine; Cocaine (IV); Cocaine Abuse; Cocaine Dependence; Contingency management; HIV risk behaviors; Heroin; Heroin Dependence; ...
  
• Behavioral Naltrexone Therapy (BNT) for Promoting Adherence to Oral Naltrexone (BNT-Oral) vs Extended Release Injectable Depot Naltrexone (Depot-BNT); a Randomized Trial. A Free Treatment for Opiate Abuse.
  ClinicalTrials.gov Identifier: NCT00577408 - Recruiting
  Opiate Dependence; Heroin Dependence
  
• Injectable Naltrexone Treatment of Alcohol Dependence in Serious Mental Illness (SMI)
  ClinicalTrials.gov Identifier: NCT00453609 - Not yet recruiting
  Schizophrenia; Schizoaffective Disorder; Bipolar Disorder; Alcohol Dependence
  
• Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation
  ClinicalTrials.gov Identifier: NCT00484692 - Completed
  Nicotine Dependence; Substance Abuse; Substance Dependence; Tobacco Dependence
  
• Employment-Based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 1
  ClinicalTrials.gov Identifier: NCT00249496 - Recruiting
  Behavior Therapy; Cocaine; Cocaine (IV); Cocaine Abuse; Contingency Management; HIV Risk Behaviors; Heroin; Heroin Dependence; Methadone; Opioid Dependence; Alcohol & Drug Use; Sexual Risk Behaviors
  
• Ph1 Marinol Interaction Study - Part 1 - 1
  ClinicalTrials.gov Identifier: NCT00438139 - Active, not recruiting
  Marijuana Dependence
  
• Smoking Cessation Medications: Efficacy, Mechanisms and Algorithms
  ClinicalTrials.gov Identifier: NCT00332644 - Active, not recruiting
  Nicotine Dependence
  
• Oral and Depot Naltrexone - 1
  ClinicalTrials.gov Identifier: NCT00218426 - Recruiting
  Heroin Dependence
  
• Topiramate for Treatment of Patients With Borderline Personality Disorder and Alcohol Dependence
  ClinicalTrials.gov Identifier: NCT00463775 - Recruiting
  Alcohol Dependence; Borderline Personality Disorder
  
• Tolerability and Safety of 30, 45, and 60 mg of Sublingual Lobeline. - 1
  ClinicalTrials.gov Identifier: NCT00519259 - Active, not recruiting
  Methamphetamine Dependence
  
• Modafinil, Sleep, and Cognition in Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00582491 - Recruiting
  Cocaine Dependence; Substance-Induced Sleep Disorder; Substance-Induced Cognitive Disorder
  
• Chantix for Treating Cocaine Dependence
  ClinicalTrials.gov Identifier: NCT00567008 - Not yet recruiting
  Cocaine Dependence
  
• Quetiapine for Bipolar Disorder and Alcohol Dependence
  ClinicalTrials.gov Identifier: NCT00457197 - Recruiting
  Bipolar Disorder; Alcohol Dependence
  
• Testing the Effectiveness of Medications Used to Treat Heroin Dependence - 1
  ClinicalTrials.gov Identifier: NCT00125515 - Completed
  Heroin Dependence
  
• A Pilot Study of Citicoline Add-on Therapy in Patients With Bipolar Disorder or Major Depressive Disorder and Amphetamine Abuse or Dependence
  ClinicalTrials.gov Identifier: NCT00377299 - Recruiting
  Amphetamine Abuse; Amphetamine Dependence; Bipolar Disorder; Major Depressive Disorder
  
• Venlafaxine to Reduce Cocaine Dependence in Depressed Individuals
  ClinicalTrials.gov Identifier: NCT00249483 - Active, not recruiting
  Cocaine-Related Disorders
  
• Targeted Naltrexone for Problem Drinkers
  ClinicalTrials.gov Identifier: NCT00369408 - Active, not recruiting
  Alcoholism; Alcohol Drinking; Alcohol Dependence
  
• Behavioral Therapy for Reduction in Smoking Craving
  ClinicalTrials.gov Identifier: NCT00449293 - Active, not recruiting
  Smoking Cessation; Tobacco Dependence
  
• Trial for the Treatment of Alcohol Dependence
  ClinicalTrials.gov Identifier: NCT00120601 - Active, not recruiting
  Alcoholism