Clinical Trial: Comparison of Different Mucoactive Agents

This study is currently recruiting patients.
Verified by The University of Texas Health Science Center at San Antonio August 2005

Sponsored by: The University of Texas Health Science Center at San Antonio
Information provided by: The University of Texas Health Science Center at San Antonio
ClinicalTrials.gov Identifier: NCT00131521

Purpose

Compare N-Acetylcysteine and Sodium Chloride to determine their efficacy in the prevention of pulmonary mucus obstruction and retention in intubated patients admitted to the STICU
Condition Intervention
mucus obstruction, ventilator management
 Drug: mucomyst versus Sodium Chloride (Saline)

MedlinePlus consumer health information 

Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Active Control, Single Group Assignment, Efficacy Study

Official Title: Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit: A Randomized, Double Blind, Controlled Trial.

Further Study Details: 
Primary Outcomes: prevention of pulmonary mucus obstruction
Secondary Outcomes: days of mechanical ventilation
Expected Total Enrollment:  160

Study start: January 2005
Last follow-up: August 2005

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • Intubated and admitted to the Surgical Trauma Intensive Care Unit(STICU)
  • subjects must be eligible to start treatment within 24 hours of their initial intubation

Exclusion Criteria:

  • patient anticipated to be extubated within 24hrs following STICU admission
  • hypersensitivity to acetylcysteine.
  • pregnancy

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00131521

Janet McCarthy, RN, CCRC      210-567-3623 
Rachelle Jonas, RN      210-567-3623 

Texas
      Univesity Hospital, San Antonio,  Texas,  78229,  United States; Recruiting
Janet McCarthy, RN  210-567-3623 
Rachelle Jonas, RN  210-567-3623 
Deborah J Levine, M.D.,  Sub-Investigator

Study chairs or principal investigators

John G. Myers, M.D.,  Principal Investigator,  University of Texas Health Science Center San Antonio   

More Information

Study ID Numbers:  034-1502-320; Not Applicable
Last Updated:  August 17, 2005
Record first received:  August 17, 2005
ClinicalTrials.gov Identifier:  NCT00131521
Health Authority: United States: Institutional Review Board
ClinicalTrials.gov processed this record on 2005-08-23



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