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Clinical Trial: Alternative Stress Management Approaches in HIV Disease
This study is no longer recruiting patients.
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Purpose
The overall purpose of the proposed study is to determine whether three short-term stress management interventions along with booster strategies will improve and sustain improvements in psychosocial functioning, quality of life, and somatic health among persons with varying stages of HIV disease. The 10-week group interventions are designed to reduce perceived stress and increase coping effectiveness and include cognitive-behavioral stress management focused on positively living (+LIVE), focused Tai Chi (TCHI) training, and spiritual growth groups (SPRT). Effects of the interventions will be evaluated immediately upon completion of the group training and at 6 months and 12 months following stress management training.
| Condition | Treatment or Intervention | Phase |
|---|---|---|
| HIV Infections | Behavior: Cognitive-behavioral relaxation (Positively Living) Behavior: Spiritual growth group Behavior: Focused Tai Chi | Phase III |
MedlinePlus related topics: AIDS
Study Type: Interventional
Study Design: Educational/Counseling/Training, Randomized, Open Label, Active Control, Crossover Assignment, Efficacy Study
Expected Total Enrollment: 392
Study start: September 2000; Study completion: May 2005
The overall purpose of the proposed study is to determine whether three short-term stress management interventions along with booster strategies will improve and sustain improvements in the domains of psychosocial functioning, quality of life, and somatic health among persons with varying stages of HIV disease. These three outcome domains, along with neuroendocrine mediation, will be measured by multiple indicators derived from the psychoneuroimmunology (PNI)paradigm. The interventions are designed to reduce perceived stress and increase coping effectiveness and include cognitive-behavioral stress management focused on positively living (+LIVE), focused Tai Chi (TCHI) training, and spiritual growth groups (SPRT). The primary aim of this randomized clinical trial is to compare the +LIVE, TCHI, and SPRT interventions to each other and to standard care received by a control group of wait-listed participants (WAIT) for effects on psychosocial functioning (perceived stress, coping patterns, social support, psychological distress), quality of life (including spiritual well-being), neuroendocrine mediation (cortisol, DHEA levels), and somatic health (disease progression, HIV-specific health status, immune status).
Eligibility
Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both
Criteria
Inclusion Criteria:
- Aware of HIV-infected diagnosis
Exclusion Criteria:
- Current psychoactive drug use
- Severe and unstable psychiatric diagnosis
- Major cognitive dysfunction
Location Information
Virginia
Virginia Commonwealth University, Richmond, Virginia, 23298-0567, United States
More Information
Record last reviewed: September 2004
Last Updated: October 13, 2004
Record first received: January 9, 2002
ClinicalTrials.gov Identifier: NCT00029237
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-04-08
Source: ClinicalTrials.gov
Cache Date: April 8, 2005

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