Beare-Stevenson cutis gyrata syndrome is a genetic disorder characterized by skin abnormalities and the premature fusion of certain bones of the skull (craniosynostosis), which prevents further growth of the skull and affects the shape of the head and face. Many of the characteristic facial features of Beare-Stevenson syndrome result from the premature fusion of the skull bones. The head is unable to grow normally, which leads to a misshapen skull, wide-set and bulging eyes, an underdeveloped upper jaw, and ear defects. Newborns with Beare-Stevenson syndrome usually have a large umbilical stump. Skin abnormalities are also characteristic of this disorder. The skin is furrowed, giving it a corrugated appearance (cutis gyrata). Additionally, thick, dark, velvety areas of skin (acanthosis nigricans) are often found on the hands and feet.