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Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients - Article


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Clinical Trial: Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients

This study is currently recruiting patients.
Verified by University Hospital Muenster August 2005

Sponsored by: University Hospital Muenster
Information provided by: University Hospital Muenster
ClinicalTrials.gov Identifier: NCT00132223

Purpose

Angiographies of the supra-aoritc vessels by magnetic imaging has become common in the recent time. So it was the purpose of this study to evaluate the imaging potential of different contrast agents.

Three contrast agents for magnetic resonance imaging are compared in angiographies of the supra-aortic arteries in a intraindividual study of 10 patients.

All applications of these contrast agents are performed with a flow of 2 ml/s. One contrast medium is applicated a second time with a reduced flow of 1 ml/s.

The angiographies of the supra-aortic vessels are evaluated by two experienced readers in a consensus reading. The signal/noise- and contrast/noise-ratio of anatomic vessel segments of the carotic and vertebral arteries are measured and compared to each other.

Condition Intervention Phase
vessel
 Drug: Contrast agent
Phase IV

MedlinePlus consumer health information 

Study Type: Interventional
Study Design: Diagnostic, Non-Randomized, Single Blind, Uncontrolled, Single Group Assignment

Official Title: Effects on the Diagnostic Accuracy of Magnetic Imaging Angiographies of the Supra-Aortic Vessels by Three Different Magnetic Resonance Contrast Agents in Patients with Headache and Dizziness or Epilepsy and Clinical Indication for an Angiography by Magnetic Imaging

Further Study Details: 
Primary Outcomes: intensity of vessels, muscle, air
Secondary Outcomes: signal/noise ratio; contrast/nose ratio
Expected Total Enrollment:  10

Study start: April 2005;  Expected completion: December 2005
Last follow-up: December 2005;  Data entry closure: December 2005

Eligibility

Ages Eligible for Study:  18 Years   -   60 Years,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • headache, epilepsia, dizziness

Exclusion Criteria:

  • pregnancy, metal implants (e.g. pacemaker), contraindication for contrast agent, multiple allergies

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00132223

Boris Buerke, MD      00492518345123    buerkeb@uni-muenster.de
Bernd Tombach, MD      00492518345123    tombach@uni-muenster.de

Germany
      University of Muenster, Dept. of Clinical Radiology, Muenster,  48129,  Germany; Recruiting
Boris Buerke, MD  00492518345123    buerkeb@uni-muenster.de 
Bernd Tombach  00492518345123    tombach@uni-muenster.de 
Bernd Tombach, MD,  Principal Investigator
Boris Buerke, MD,  Sub-Investigator

Study chairs or principal investigators

Bernd Tombach, MD,  Study Chair,  University of Muenster, Dept. of Clinical Radiology   

More Information

Study ID Numbers:  0710/2004-IKR
Last Updated:  August 18, 2005
Record first received:  August 18, 2005
ClinicalTrials.gov Identifier:  NCT00132223
Health Authority: Germany: Federal Institute for Drugs and Medicinal Devices
ClinicalTrials.gov processed this record on 2005-08-23

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Page Updated: September 6, 2005
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