Coenzyme Q (CoQ), also known as ubiquinone or ubiquinol, is a biologically active quinone with an isoprenoid side chain, related in structure to vitamin K and vitamin E.


... Coenzyme Q-10 is used extensively in Japan, and its use is more common in Europe and western Asia than it is in the United States. However, specific coenzyme Q-10 products have been given orphan drug status in the United States. An orphan drug has received FDA approval because it shows effectiveness for treating severe or rare diseases that usually have few other treatment options. In the United States, designated coenzyme Q-10 products are used to treat Huntington’s disease, childhood heart failure, and rare, inherited defects in mitochondria, which are tiny structures within body cells. Huntington’s disease (also called Huntington’s chorea) is an hereditary condition that involves increasing loss of muscle control and decreasing mental function. Generally not apparent until adulthood, Huntington’s disease may be passed to children before parents realize they have it. Because mitochondria are responsible for energy production by each cell, many of them are found in cells that use lots of energy – such as muscle cells. Cells that use little energy have few mitochondria. If the mitochondria do not function properly, progressively worsening symptoms that may include muscle weakness, nerve damage, seizures, stroke-like episodes, and eventually death may result. Although coenzyme Q-10 seems to be an effective treatment to prevent, delay, or decrease the symptoms of inherited mitochondrial defects in some individuals, it may take 6 months or longer to produce a noticeable response. ...
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Coenzyme Q (CoQ), also known as ubiquinone or ubiquinol, is a biologically a ...
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