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Reserpine |
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Reserpine Systematic (IUPAC) name methyl-11,17α-dimethoxy-18β-[(3,4,5-trimethoxybenzoyl) oxy]-3β,20α-yohimban-16β-carboxylate[1] Identifiers CAS number 50-55-5 ATC code C02AA02 PubChem 5770 DrugBank APRD00472 Chemical data Formula C33H40N2O9 Mol. weight 608.679 g/mol Pharmacokinetic data Bioavailability 50% Metabolism gut/liver Half life phase 1 = 4.5h, phase 2 = 271h, average = 33h Excretion 62% feces / 8% urine Therapeutic considerations Pregn ...
Wikipedia - [full article]
Reserpine Clinical Trials
- Reserpine for the Treatment of Cocaine Dependence - 1
ClinicalTrials.gov Identifier: NCT00033033 - Active, not recruiting
Cocaine-Related Disorders; Substance-Related Disorders
- A Phase 1 Parallel-Group, Double-Blind, Placebo-Controlled Cardiovascular and Behavioral Study Assessing Interactions Between Single Doses of Oral Reserpine and Intravenous Methamphetamine - 1
ClinicalTrials.gov Identifier: NCT00267657 - Active, not recruiting
Amphetamine-Related Disorders
- Systolic Hypertension in the Elderly Program (SHEP) (Pilot Study)
ClinicalTrials.gov Identifier: NCT00000499 - Completed
Cardiovascular Diseases; Heart Diseases; Hypertension; Vascular Diseases
- Systolic Hypertension in the Elderly Program (SHEP)
ClinicalTrials.gov Identifier: NCT00000514 - Completed
Cardiovascular Diseases; Cerebrovascular Disorders; Heart Diseases; Hypertension
Resources
- Reserpine (Drug Digest)
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