Nicotine Gum |
Nicorette; Nicotine polacrilex |
Clinical Trial: Brain Reaction to Treatment of Nicotine Dependence
This study is currently recruiting patients.
|
Purpose
The purpose of the study is to determine how the treatments for cigarette craving work.
Hypothesis: During exposure to cigarette-related cues, heavy smokers will have greater reductions in regional brain activation from before to after both forms of active treatments than from before to after placebo.
| Condition | Treatment or Intervention | Phase |
|---|---|---|
| Nicotine Dependence | Drug: Zyban | Phase I |
MedlinePlus related topics: Smoking
Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Pharmacokinetics/Dynamics Study
Official Title: Neural Substrates of Treatment for Nicotine Dependence
Study start: October 2002; Expected completion: September 2005
Eligibility
Ages Eligible for Study: 21 Years - 60 Years, Genders Eligible for Study: Both
Criteria
Inclusion Criteria:
- Heavy smoker, more than one pack per day
- Free of medical conditions or medications that affect brain activity
- Not pregnant
Location and Contact Information
California
VA Greater Los Angeles Healthcare System, Los Angeles, California, 90073, United States; Recruiting
Arthur Brody, M.D., Principal Investigator
More Information
Record last reviewed: April 2005
Last Updated: April 14, 2005
Record first received: April 14, 2005
ClinicalTrials.gov Identifier: NCT00108173
Health Authority: United States: Federal Government
ClinicalTrials.gov processed this record on 2005-05-03
Source: ClinicalTrials.gov
Cache Date: May 4, 2005
Resources
- Nicorette (Drug Digest)
- Nicotine Gum (Drug Digest)

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