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Nelfinavir |
Viracept |
Nelfinavir Systematic (IUPAC) name 2-[2-hydroxy-3-(3-hydroxy-2-methyl-benzoyl) amino-4-phenylsulfanyl-butyl] -N-tert-butyl- 1,2,3,4,4a,5,6,7,8,8a- decahydroisoquinoline-3-carboxamide Identifiers CAS number 159989-64-7 ATC code J05AE04 PubChem 64143 DrugBank APRD00003 Chemical data Formula C32H45N3O4S Mol. weight 567.784 g/mol Physical data Melt. point 349.94°C (662°F) Pharmacokinetic data Bioavailability Uncertain; improved by taking with food Protein b ...
Wikipedia - [full article]
Nelfinavir Clinical Trials
- Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy
ClinicalTrials.gov Identifier: NCT00008554 - Active, not recruiting
HIV Infections
- Treatment with Nelfinavir or Efavirenz of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00005000 - Active, not recruiting
HIV Infections
- Safety, Tolerability, and Anti-HIV Activity of DMP 266 (Efavirenz) in Combination with Nelfinavir in HIV-Positive Children
ClinicalTrials.gov Identifier: NCT00000893 - Active, not recruiting
HIV Infections
- A Randomized Trial of the Efficacy and Safety of a Strategy of Starting with Nelfinavir Versus Ritonavir Added to Background Antiretroviral (AR) Nucleoside Therapy in HIV-Infected Individuals with CD4+ Cell Counts Less than or Equal to 200/mm3
ClinicalTrials.gov Identifier: NCT00000859 - Active, not recruiting
HIV Infections
- Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected Children
ClinicalTrials.gov Identifier: NCT00002219 - Active, not recruiting
HIV Infections
- A Study to Evaluate the Safety and Tolerance of Nelfinavir (NFV) Given with Zidovudine (ZDV) and Lamivudine (3TC) in HIV-Positive Pregnant Women and Their Infants
ClinicalTrials.gov Identifier: NCT00000887 - Active, not recruiting
HIV Infections; Pregnancy
- Comparison of GW433908/Ritonavir to Nelfinavir When Used with Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs
ClinicalTrials.gov Identifier: NCT00009061 - Active, not recruiting
HIV Infections
- A Study To Estimate The Effect Of Omeprazole On The Pharmacokinetics Of Nelfinavir In Healthy Subjects
ClinicalTrials.gov Identifier: NCT00251030 - Completed
- Nelfinavir Mesylate in Treating Patients With Recurrent, Metastatic, or Unresectable Liposarcoma
ClinicalTrials.gov Identifier: NCT00233948 - Recruiting
Sarcoma
- A Study to Compare Two Different Anti-HIV Drug Regimens
ClinicalTrials.gov Identifier: NCT00000924 - Active, not recruiting
HIV Infections
- Treatment with Combinations of Several Antiviral Drugs in Infants and Young Children with HIV Infection
ClinicalTrials.gov Identifier: NCT00000872 - Active, not recruiting
HIV Infections
- A Study of the Safety and Effectiveness of Treating Advanced AIDS Patients between Ages 4 and 22 with 7 Drugs, Some at Higher than Usual Doses
ClinicalTrials.gov Identifier: NCT00001108 - Active, not recruiting
HIV Infections
- A Study on the Management of Combination Anti-HIV Drug Therapy in HIV-Positive Children with Prior Treatment
ClinicalTrials.gov Identifier: NCT00000902 - Active, not recruiting
HIV Infections
- A Study to Compare Two Anti-HIV Combination Therapies Each Containing Saquinavir in HIV-Positive Children
ClinicalTrials.gov Identifier: NCT00000913 - Active, not recruiting
HIV Infections
- Nelfinavir and M8 Drug-Level Monitoring in HIV-1 Infection
ClinicalTrials.gov Identifier: NCT00205283 - Recruiting
HIV Infections
- Effectiveness of Treating HIV-Positive Patients with an HIV Vaccine (Remune)
ClinicalTrials.gov Identifier: NCT00005002 - Active, not recruiting
HIV Infections
- Safety and Effectiveness of Giving Indinavir and Nelfinavir to HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002375 - Completed
HIV Infections
- Combination Treatment Using Capravirine (AG1549), Nelfinavir, and Two Nucleoside Reverse Transcriptase Inhibitors in HIV Patients Who Failed Initial Combination Therapy
ClinicalTrials.gov Identifier: NCT00004985 - Completed
HIV Infections
- The Effects of Staggered Dosing on Interactions Between Paired Combinations of Nelfinavir, Ritonavir, and Saquinavir
ClinicalTrials.gov Identifier: NCT00000898 - Completed
HIV Infections
- A Study of Ritonavir (ABT-538) When Used with Nelfinavir in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002201 - Completed
HIV Infections
- Paclitaxel in Treating Patients With AIDS-Related Kaposi's Sarcoma
ClinicalTrials.gov Identifier: NCT00003008 - Active, not recruiting
epidemic Kaposi's sarcoma; recurrent Kaposi's sarcoma
- Effectiveness of Adding Interleukin-2 to Anti-HIV Drugs in Patients Recently Infected with HIV
ClinicalTrials.gov Identifier: NCT00006441 - Recruiting
HIV Infections
- When to Start Anti-HIV Drugs in Children Infected With HIV
ClinicalTrials.gov Identifier: NCT00234091 - Recruiting
HIV Infections
- The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken Stavudine
ClinicalTrials.gov Identifier: NCT00002381 - Completed
HIV Infections
- The Effectiveness of Nelfinavir and Efavirenz, Used Alone or Together, Combined with Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00001087 - Completed
HIV Infections
- The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs
ClinicalTrials.gov Identifier: NCT00017758 - Completed
HIV Infections; HIV Seronegativity; Lipodystrophy
- A Pilot Open Label Trial of HIV Therapy with d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects with Early Asymptomatic HIV Infection
ClinicalTrials.gov Identifier: NCT00002176 - Completed
HIV Infections
- A Pilot Open Label Trial of HIV Therapy with d4T (Stavudine), ddI (Didanosine), Nelfinavir and Hydroxyurea in Subjects with Recent HIV Infection
ClinicalTrials.gov Identifier: NCT00002177 - Completed
HIV Infections
- A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease Inhibitors
ClinicalTrials.gov Identifier: NCT00002235 - Completed
HIV Infections
- Intensive Pharmacokinetics of the Nelfinavir Rifabutin Interaction in Patients with HIV-Related Tuberculosis Treated with a Rifabutin-Based Regimen
ClinicalTrials.gov Identifier: NCT00023400 - Completed
HIV Infections; Tuberculosis
- Safety of VIRACEPT® 625 Mg During Pregnancy
ClinicalTrials.gov Identifier: NCT00246610 - Recruiting
HIV Infections; Pregnancy
- Intensive Pharmacokinetics of the Nelfinavir-Rifabutin Interaction in Patients with HIV-Related Tuberculosis Treated with a Rifabutin-Based Regimen
ClinicalTrials.gov Identifier: NCT00018083 - Recruiting
Tuberculosis; HIV Infections
- Addition of Efavirenz or Nelfinavir to a Lamivudine/Zidovudine/Indinavir HIV Treatment Regimen
ClinicalTrials.gov Identifier: NCT00000903 - Completed
HIV Infections
- Study of Zidovudine/Lamivudine and Nevirapine for Reduction of Mother-to-Child HIV Transmission During Breastfeeding
ClinicalTrials.gov Identifier: NCT00146380 - Recruiting
HIV Infections
- Nelfinavir in Treating Patients With Metastatic, Refractory, or Recurrent Solid Tumors
ClinicalTrials.gov Identifier: NCT00436735 - Recruiting
Colorectal Cancer; Gastrointestinal Carcinoid Tumor; Head and Neck Cancer; Islet Cell Tumor; Lung Cancer; Metastatic Cancer; Neuroendocrine Carcinoma of the Skin; Ovarian Cancer; Pheochromocytoma; Sarcoma; Unspecified Adult Solid Tumor, Protocol Specific
- Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission
ClinicalTrials.gov Identifier: NCT00099359 - Recruiting
Disease Transmission, Vertical; Vertical Transmission; HIV Infections
- An Open Label Study To Evaluate The Safety and Kinetics of Nelfinavir in Subjects with HIV and Hepatitis C
ClinicalTrials.gov Identifier: NCT00141284 - Completed
HIV Infections; Hepatitis C viral Infection
- Effectiveness of a New Anti-HIV Drug (AG1549) Plus Viracept (Nelfinavir) Plus Combivir (Zidovudine/Lamivudine) in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00004999 - Suspended
HIV Infections
- A Comparison of Nelfinavir Plus Saquinavir Plus Delavirdine or 3TC/ZDV Versus Nelfinavir Plus 3TC/ZDV in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001094 - Terminated
HIV Infections
- A Comparison of Atazanavir and Nelfinavir, Each in Combination with 2 NRTIs, in Patients Who Have Failed Treatments without a Protease Inhibitor
ClinicalTrials.gov Identifier: NCT00028067 - Terminated
HIV Infections
- Thorough QT Study of Nelfinavir
ClinicalTrials.gov Identifier: NCT00312182 - Completed
Healthy Normal Volunteers
- Determining the Amount of Time Needed for Nelfinavir to Boost the Immune System in Adults
ClinicalTrials.gov Identifier: NCT00346619 - Completed
Immune Response
- A Study of Indinavir Plus Ritonavir Plus Two NRTIs vs. Nelfinavir Plus Two NRTIs in HIV Positive Patients
ClinicalTrials.gov Identifier: NCT00541463 - Completed
HIV Infections
- Viracept Expanded Access Program
ClinicalTrials.gov Identifier: NCT00002165 - Completed
HIV Infections
- Drug Interactions Among Anti-HIV Agents
ClinicalTrials.gov Identifier: NCT00001766 - Completed
HIV Infection
- A Study of 141W94 in Combination with Other Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002372 - Completed
HIV Infections
- A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations
ClinicalTrials.gov Identifier: NCT00002430 - Completed
HIV Infections
- A Study of Viracept in HIV-Positive Women
ClinicalTrials.gov Identifier: NCT00002171 - Completed
HIV Infections
- A Comparison of Two Triple-Drug Combinations in Patients Who Have Never Been Treated with Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002411 - Completed
HIV Infections
- Study of a New Protease Inhibitor, BMS-232632, in Combination with Other Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002240 - Completed
HIV Infections
- Safety and Effectiveness of Four Anti-HIV Drug Combinations in HIV-Infected Children and Teens
ClinicalTrials.gov Identifier: NCT00001091 - Completed
HIV Infections
- A Study of an Adherence Plan to Help HIV-Positive Patients Take Their First Anti-HIV Medications Correctly
ClinicalTrials.gov Identifier: NCT00001122 - Completed
HIV Infections
- A Study on the Effect of Chemotherapy Combined with Anti-HIV Drugs in HIV-Positive Patients
ClinicalTrials.gov Identifier: NCT00000899 - Completed
HIV Infections
- A Comparison of Two Multi-Drug Therapies in HIV-Infected Patients Who Have Never Received Anti-HIV Treatment
ClinicalTrials.gov Identifier: NCT00002216 - Completed
HIV Infections
- A Study of the Effectiveness of Different Anti-HIV Treatments in HIV-Positive Individuals Who Have Been on a Protease Inhibitor-Containing Drug Regimen for at Least 16 Weeks
ClinicalTrials.gov Identifier: NCT00000914 - Completed
HIV Infections
- Comparison of Two Anti-HIV Regimens that Include One of Two Forms of Didanosine (ddI)
ClinicalTrials.gov Identifier: NCT00002224 - Completed
HIV Infections
- Phase I Study of Safety, Tolerability, and Pharmacokinetics of Viracept in HIV-1 Infected Children and Exposed Infants
ClinicalTrials.gov Identifier: NCT00002164 - Completed
HIV Infections
- A Study to Compare the Safety and Effectiveness of Two Dosing Schedules of Lamivudine in Combination with Two Other Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002442 - Completed
HIV Infections
- A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive
ClinicalTrials.gov Identifier: NCT00002215 - Completed
HIV Infections
- Safety and Effectiveness of Giving Combinations of Three or Four Anti-HIV Drugs to HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002211 - Completed
HIV Infections
- The Safety and Effectiveness of Two Forms of Saquinavir Combined with Other Anti-HIV Drugs in HIV-Infected Infants and Children
ClinicalTrials.gov Identifier: NCT00002380 - Completed
HIV Infections
- A Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00005106 - Completed
HIV Infections
- A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir
ClinicalTrials.gov Identifier: NCT00000892 - Completed
HIV Infections
- A Study of Saquinavir Soft Gelatin Capsules Combined with Other Anti-HIV Drugs in HIV-1 Infected Patients
ClinicalTrials.gov Identifier: NCT00002374 - Completed
HIV Infections
- A Study on Possible Interactions Between Protease Inhibitors (Anti-HIV Drugs) and Drugs Which Lower the Level of Fat in Your Blood
ClinicalTrials.gov Identifier: NCT00000941 - Completed
HIV Infections
- A Study of Capravirine Plus VIRACEPT Plus Two Nucleoside Reverse Transcriptase Inhibitors in HIV-Infected Patients Who Failed Previous Anti-HIV Treatments
ClinicalTrials.gov Identifier: NCT00006211 - Completed
HIV Infections
- A Study to determine how and why HIV-Infected subjects on anti-viral treatment develop Lipodystrophy
ClinicalTrials.gov Identifier: NCT00006190 - Completed
HIV Infections; Lipodystrophy
- A Study of 1592U89 in Combination with Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002440 - Completed
HIV Infections
- Drug Interactions of Amprenavir and Efavirenz, in Combination with a Second Protease Inhibitor, in HIV-Negative Volunteers
ClinicalTrials.gov Identifier: NCT00005762 - Completed
HIV Infections
- Safety and Tolerance of Indinavir plus Ritonavir in HIV-Positive Patients Failing Therapy with Amprenavir, Nelfinavir, or Saquinavir
ClinicalTrials.gov Identifier: NCT00001133 - Completed
HIV Infections
- Potent Antiviral Therapy for Critically Ill HIV Infected Patients Admitted to Intensive Care
ClinicalTrials.gov Identifier: NCT00028327 - Completed
HIV Infections
- Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients with Tuberculosis
ClinicalTrials.gov Identifier: NCT00004736 - Completed
HIV Infections; Tuberculosis
- A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected Patients
ClinicalTrials.gov Identifier: NCT00002378 - Completed
HIV Infections
- A Study on Amprenavir in Combination with Other Anti-HIV Drugs in HIV-Positive Patients
ClinicalTrials.gov Identifier: NCT00000912 - Completed
HIV Infections
- A Study to Evaluate the Long-Term Effectiveness of Three Anti-HIV Drug Treatments in HIV-Positive Patients Who Have Never Been Exposed to Highly Active Antiretroviral Therapy (HAART)
ClinicalTrials.gov Identifier: NCT00000922 - Completed
HIV Infections
- Effectiveness of Anti-HIV Drugs in Patients Who Have Not Received Previous Anti-HIV Drugs During Different Stages of HIV Infection
ClinicalTrials.gov Identifier: NCT00006443 - Completed
HIV Infections
- A Study of Viracept in AIDS Patients with Cytomegalovirus Retinitis
ClinicalTrials.gov Identifier: NCT00002169 - Completed
Cytomegalovirus Retinitis; HIV Infections
- Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use with Certain Anti-HIV Drugs in HIV-Infected Women
ClinicalTrials.gov Identifier: NCT00016601 - Completed
HIV Infections
- Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination with Nucleoside Analogs: A Rollover Study for ACTG 320
ClinicalTrials.gov Identifier: NCT00000885 - Completed
HIV Infections
- Evaluation of an Anti-HIV Drug Combination That Includes a Coated Form of Didanosine (ddI EC) Compared to a Typical Anti-HIV Drug Regimen
ClinicalTrials.gov Identifier: NCT00002429 - Completed
HIV Infections
- A Study of Saquinavir Soft Gel Capsules (SGC) Used in Combination With Two Other Anti-HIV Drugs in Patients with HIV-Associated Kidney Disease
ClinicalTrials.gov Identifier: NCT00002397 - Completed
HIV Infections; AIDS-Associated Nephropathy
- A Phase IIIB Open-Label, Comparative Study to Evaluate Saquinavir Soft Gel Capsule (SGC) Treatment in Combination with Other Antiretrovirals in HIV-1 Infected Antiretroviral-Naive Patients
ClinicalTrials.gov Identifier: NCT00002178 - Completed
HIV Infections
- A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection
ClinicalTrials.gov Identifier: NCT00000919 - Completed
HIV Infections
- Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During Pregnancy
ClinicalTrials.gov Identifier: NCT00017719 - Completed
HIV Infections; Pregnancy
- A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment Failure
ClinicalTrials.gov Identifier: NCT00000918 - Completed
HIV Infections
- A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients with CD4 <= 500 cells/mm3
ClinicalTrials.gov Identifier: NCT00002185 - Completed
Sarcoma, Kaposi; HIV Infections
- Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success with Nelfinavir
ClinicalTrials.gov Identifier: NCT00002220 - Completed
HIV Infections
- A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients without Previous Anti-HIV Drug Therapy
ClinicalTrials.gov Identifier: NCT00004583 - Completed
HIV Infections
- A Study of Viracept in AIDS Patients with Mycobacterium Avium Complex Disease (MAC)
ClinicalTrials.gov Identifier: NCT00002170 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients with Advanced HIV Infection
ClinicalTrials.gov Identifier: NCT00000895 - Completed
Mycobacterium avium-intracellulare Infection; HIV Infections
- A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies with Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (R
ClinicalTrials.gov Identifier: NCT00002184 - Completed
HIV Infections
- A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir
ClinicalTrials.gov Identifier: NCT00002423 - Completed
HIV Infections
- Safety and Effectiveness of a New Anti-HIV Drug (AG1549) in Combination With Other Anti-HIV Drugs in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00004998 - Suspended
HIV Infections
- Evaluation of Therapeutic Drug Monitoring of Protease Inhibitors On Virologic Success and Tolerance of HAART
ClinicalTrials.gov Identifier: NCT00122590 - Terminated
HIV Infections
- Safety and Effectiveness of 3 Anti-HIV Treatments in Patients Who Have Failed Previous Treatments Containing Nelfinavir
ClinicalTrials.gov Identifier: NCT00006326 - Terminated
HIV Infections
Resources
- Nelfinavir (Drug Digest)
- Viracept (Drug Digest)
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