Thiothixene Capsules |
Navane |
Article: Thiothixene
| Image:Thiothixene.png | |
| Thiothixene | |
| Systematic (IUPAC) name | |
| N,N-dimethyl-9- [3-(4-methylpiperazin-1-yl)propylidene]- thioxanthene-2-sulfonamide | |
| Identifiers | |
| CAS number | 5591-45-7 |
| ATC code | N05AF04 |
| PubChem | 5454 |
| DrugBank | none |
| Chemical data | |
| Formula | C23H29N3O2S2 |
| Mol. weight | 443.627 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Routes | ? |
Thiothixene (sold as Navane®) is a thioxanthene drug used as a typical antipsychotic medication. It is a thioxanthene derivative and is the cis isomer of N,Ndimethyl- 9-[3-(4-methyl-1-piperazinyl)-propylidene] thioxanthene-2-sulfonamide.
Although widely used in the treatment of schizophrenia for several decades, thiothixene is seldom used today in favor of atypical antipsychotics such as olanzapine.
| Antipsychotics (N05A) edit |
| Phenothiazine typical antipsychotics: {A01-Chlorpromazine} {B02-Fluphenazine} {B03-Perphenazine} {B04-Prochlorperazine} {B06-Trifluoperazine} {C02-Thioridazine} {C03-Mesoridazine} Other typical antipsychotics: {D01-Haloperidol} {D08-Droperidol} {E02-Molindone} {F01-Flupentixol} {F03-Chlorprothixene} {F04-Thiothixene} {G02-Pimozide} {H01-Loxapine} {Sulforidazine} Atypical antipsychotics: {E03-Sertindole} {E04-Ziprasidone} {H02-Clozapine} {H03-Olanzapine} {H04-Quetiapine} {L01-Sulpiride} {L05-Amisulpride} {X08-Risperidone/Paliperidone} {X11-Zotepine} {X12-Aripiprazole} |
Categories: Pharmacology stubs | Typical antipsychotics
Resources
- Navane (Drug Digest)
- Thiothixene Capsules (Drug Digest)

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