Nafcillin Sodium Injection |
Nallpen; Unipen Injection |
Article: Nafcillin
| Image:Nafcillin.png | |
| Nafcillin | |
| Systematic (IUPAC) name | |
| 7-[(2-ethoxynaphthalen-1-yl) carbonylamino]- 3,3-dimethyl-6-oxo-2-thia-5-azabicyclo [ 3.2.0] heptane-4-carboxylic acid | |
| Identifiers | |
| CAS number | 985-16-0 |
| ATC code | ? |
| PubChem | 8982 |
| DrugBank | APRD01130 |
| Chemical data | |
| Formula | C21H22N2O5S |
| Mol. weight | 414.476 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | <30% hepatic |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. | ? |
| Legal status | |
| Routes | ? |
Nafcillin sodium is an beta-lactam antibiotic related to penicillin. As a beta-lactamase-resistant penicillin, it is used to treat infections caused by Gram-positive bacteria, particularly species of Staphylococci, that are resistant to other penicillins.
Administration
Nafcillin can be given either orally (UnipenĀ®) or by injection (NallpenĀ®)
Side effects
As with all penicillins, serious life-threatening allergic reactions can occur.
Milder side effects include:
- Nausea and vomiting
- Diarrhea, often due to suppression of normal gastrointestinal bacteria. Occasionally, this leads to a more serious super-infection with an organism like Clostridium difficile
- Abdominal pain
- Yeast infections (thrush) affecting the mouth and tongue or vagina
Categories: Beta-lactam antibiotics | Pharmacology stubs
Resources
- Nafcillin Sodium Injection (Drug Digest)
- Nallpen (Drug Digest)

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