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Lovastatin |
Mevacor |
Lovastatin Systematic (IUPAC) name [8-[2-(4-hydroxy-6-oxo-oxan-2-yl)ethyl] -3,7-dimethyl-1,2,3,7,8,8a- hexahydronaphthalen- 1-yl] 2-methylbutanoate Identifiers CAS number 75330-75-5 ATC code C10AA02 PubChem 53232 DrugBank APRD00370 Chemical data Formula C24H36O5 Mol. weight 404.54 g/mol Pharmacokinetic data Bioavailability ? Protein binding >95% Metabolism ? Half life 5.3 hours Excretion ? Therapeutic considerations Pregnancy ca ...
Wikipedia - [full article]
Lovastatin Clinical Trials
- Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis
ClinicalTrials.gov Identifier: NCT00004346 - Recruiting
Cerebrotendinous Xanthomatosis
- Study of Effectiveness of Lovastatin to Prevent Radiation-Induced Rectal Injury
ClinicalTrials.gov Identifier: NCT00580970 - Recruiting
Prostate Cancer
- Trial to Evaluate the Safety of Lovastatin in Adults With Neurofibromatosis Type I (NF1)
ClinicalTrials.gov Identifier: NCT00352599 - Recruiting
Neurofibromatosis 1
- Lovastatin in Treating Patients at High Risk of Recurrent Melanoma
ClinicalTrials.gov Identifier: NCT00462280 - Recruiting
Melanoma (Skin)
- Dose Escalation Phase I/II Study of Lovastatin With High-Dose Cytarabine for Refractory or Relapsed AML
ClinicalTrials.gov Identifier: NCT00583102 - Recruiting
Acute Myeloid Leukemia
- Phase II Trial - Breast Cancer Chemoprevention by Lovastatin
ClinicalTrials.gov Identifier: NCT00285857 - Recruiting
Breast Cancer
- Lovastatin for the Treatment of Mildly Active Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00302952 - Recruiting
Rheumatoid Arthritis
- The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients with Intermittent Claudication - TROPIC
ClinicalTrials.gov Identifier: NCT00071266 - Completed
Intermittent Claudication; Peripheral Vascular Disease
- Effect of Niacin Extended Release and Lovastatin tablets on Walking in Patients with Intermittent Claudication (ICPOP)
ClinicalTrials.gov Identifier: NCT00062556 - Completed
Intermittent Claudication; Peripheral Vascular Disease
- Efficacy Study of Extended-Release Niacin/Lovastatin Versus Usual Care
ClinicalTrials.gov Identifier: NCT00345657 - Completed
Hyperlipidemia; Mixed Hyperlipidemia; Dyslipidemia
- MARS - Monitored Atherosclerosis Regression Study
ClinicalTrials.gov Identifier: NCT00116870 - Completed
Atherosclerosis; Coronary Artery Disease
- Post Coronary Artery Bypass Graft (CABG) Study
ClinicalTrials.gov Identifier: NCT00000463 - Completed
Cardiovascular Diseases; Coronary Disease; Heart Diseases; Myocardial Ischemia
- Familial Atherosclerosis Treatment Study (FATS)
ClinicalTrials.gov Identifier: NCT00000512 - Completed
Cardiovascular Diseases; Coronary Arteriosclerosis; Coronary Disease; Heart Diseases; Myocardial Ischemia
- Cholesterol Reduction in Seniors Program (CRISP)
ClinicalTrials.gov Identifier: NCT00000477 - Completed
Atherosclerosis; Cardiovascular Diseases; Coronary Disease; Heart Diseases; Hypercholesterolemia; Myocardial Ischemia
- Asymptomatic Carotid Artery Plaque Study (ACAPS)
ClinicalTrials.gov Identifier: NCT00000469 - Completed
Cardiovascular Diseases; Carotid Stenosis; Cerebral Arteriosclerosis; Cerebrovascular Disorders; Heart Diseases; Vascular Diseases
Resources
- Lovastatin (Drug Digest)
- Lovastatin (Cleveland Clinic)
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