Zalcitabine (2'-3'-dideoxycytidine, ddC), is a derivative of the naturally existing deoxycytidine, made by replacing the hydroxyl group in position 3' with a hydrogen. It is phosphorylated in the T cell into its active triphosphate form, ddCTP. This active metabolite works as a substrate for the reverse transcriptase, and also by incorporation into the viral DNA, hence terminating the chain elongation due to the missing hydroxyl group. ...

GoldBamboo

... ZALCITABINE, ddC (Hivid®) is an antiviral drug called a nucleoside reverse transcriptase inhibitor or NRTI. Zalcitabine is used to treat human immunodeficiency virus (HIV) infection. Zalcitabine may reduce the amount of HIV in the blood and increase the number of CD4 cells (T-cells) in the blood. Zalcitabine is used in combination with other drugs to treat the HIV virus. Zalcitabine will not cure or prevent HIV infection or AIDS. You may still develop other infections or conditions associated with HIV. Generic zalcitabine tablets are not yet available. ...
Drug Digest - more...

Zalcitabine Systematic (IUPAC) name 4-amino-1-[5-(hydroxymethyl) ...
Wikipedia - [full article]

Resources