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Teniposide

EPT; VM-26; Vumon 




Article: Teniposide

Image:Teniposide.png
Teniposide
Systematic (IUPAC) name
 ?
Identifiers
CAS number 29767-20-2
ATC code L01CB02
PubChem 34698
DrugBank APRD00649
Chemical data
Formula C32H32O13S
Mol. weight 656.655 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 5 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Teniposide is a medication prescribed mainly used to treat childhood acute lymphocytic leukemia. It is in a class of drugs known as podophyllotoxin derivatives and slows the growth of cancer cells in the body. Common side effects include nausea, vomiting, diarrhea, and thinned or brittle hair. Its brand name is "Vumon" and it is also known as VM-26.

The medication is injected though a vein and burns if it leaks under the skin. It is sometimes used in combination with other anticancer drugs.

A major problem with Teniposide is the lowered count of white blood cells 1-2 weeks after treatment. Though they should return to normal after 3-4 weeks, the decreased count puts a user at a risk of infection. The same also occurs for platelets.

Retrieved from "http://en.wikipedia.org/wiki/Teniposide"

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November 28, 2009



Page Updated: July 22, 2006
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