Article: Flurazepam

Flurazepam
Systematic (IUPAC) name
9-chloro-2-(2-diethylaminoethyl)- 6-(2-fluorophenyl)-2,5-diazabicyclo[5.4.0]undeca- 5,8,10,12-tetraen-3-one
Identifiers
CAS number	17617-23-1
ATC code	N05CD01
PubChem	3393
DrugBank	APRD00983
Chemical data
Formula	C21H23ClFN3O
Mol. weight	387.88
Pharmacokinetic data
Bioavailability	83%
Metabolism	Hepatic
Half life	40-250 hours
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status	Schedule IV(US)
Routes	Oral

Flurazepam (marketed under the brand name Dalmane®) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.

It has the longest half-life of all of the benzodiazepines (40-250 hours), and may stay in the bloodstream for up to four days.

It is used for short-term treatment of patients with insomnia.

The most common adverse effects are dizziness, drowsiness, lightheadedness and ataxia.

Flurazepam is a Schedule IV drug under the Convention on Psychotropic Substances[1].