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Daptomycin |
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Image:Daptomycin.png Daptomycin Systematic (IUPAC) name ? Identifiers CAS number 103060-53-3 ATC code ? PubChem ? DrugBank BTD00111 Chemical data Formula C72H101N17O26 Mol. weight 1619.7086 g/mol Pharmacokinetic data Bioavailability Not applicable Protein binding 92% Metabolism unknown Half life 7 days Excretion renal (78%) Therapeutic considerations Pregnancy cat. B Legal status Rx only (US) Routes IV only Daptomycin is a ...
Wikipedia - [full article]
Daptomycin Clinical Trials
- Daptomycin in Treating Neutropenia and Fever in Patients With Cancer
ClinicalTrials.gov Identifier: NCT00335478 - Active, not recruiting
Fever, Sweats, and Hot Flashes; Infection; Neutropenia; Unspecified Adult Solid Tumor, Protocol Specific
- Daptomycin in the Treatment of Catheter-Related Staphylococcus Aureus
ClinicalTrials.gov Identifier: NCT00507247 - Active, not recruiting
Staphylococcus Aureus
- Daptomycin as an Adjuvant Agent in the Treatment of Enterococcal Native Valve Endocarditis.
ClinicalTrials.gov Identifier: NCT00401960 - Recruiting
Endocarditis, Bacterial
- A Pilot Study of Daptomycin for Antimicrobial Prophylaxis
ClinicalTrials.gov Identifier: NCT00572260 - Not yet recruiting
Staphylococcal Infections
- Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Methicillin-Resistant Staphylococcus Aureus and/or Coagulase-Negative Staphylococci
ClinicalTrials.gov Identifier: NCT00428844 - Recruiting
Osteomyelitis
- Pharmacokinetic Study of Single Dose Daptomycin in Pediatric Patients with Gram Positive Infection for Which They Are Receiving Standard Antibiotics.
ClinicalTrials.gov Identifier: NCT00136292 - Completed
Gram positive infection
- Daptomycin in the Treatment of Subjects with Infective Endocarditis or Bacteremia due to S. aureus
ClinicalTrials.gov Identifier: NCT00093067 - Completed
Bacterial Endocarditis; Bacteremia
- Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-Structure Infections
ClinicalTrials.gov Identifier: NCT00463801 - Recruiting
Staphylococcal Skin Infections
- Safety Study to Evaluate Daptomycin in Non-Infected Adults Who Are Either on Hemodialysis or Continuous Ambulatory Peritoneal Dialysis
ClinicalTrials.gov Identifier: NCT00490737 - Not yet recruiting
End-Stage Renal Disease
- Efficacy and Safety of Daptomycin Versus Vancomycin or Teicoplanin for Treatment of Complicated Skin and Soft Tissue Infections
ClinicalTrials.gov Identifier: NCT00430937 - Recruiting
Skin Diseases, Infectious; Soft Tissue Infections
- Daptomycin for the Treatment of Infections Due to Gram-positive Bacteria
ClinicalTrials.gov Identifier: NCT00055198 - Completed
Gram-Positive Bacterial Infections
- Daptomycin Study - Collection of Pharmacokinetic Samples in Patients With Renal Failure
ClinicalTrials.gov Identifier: NCT00573898 - Not yet recruiting
Renal Failure
- Daptomycin for the Treatment of Severe Necrotizing Soft-Tissue Infections.
ClinicalTrials.gov Identifier: NCT00261807 - Recruiting
Severe Necrotizing Fasciitis; Severe Necrotizing Skin and Soft Tissue Infections; Fournier's Gangrene
- Daptomycin in the Treatment of Patients with Renal Insufficiency and Complicated Skin and Skin Structure Infections
ClinicalTrials.gov Identifier: NCT00102947 - Terminated
Soft Tissue Infections
- Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or Erysipelas
ClinicalTrials.gov Identifier: NCT00295178 - Completed
Cellulitis
- Phase 2 Safety and Efficacy Study of Daptomycin in Complicated Skin and Skin Structure Infections
ClinicalTrials.gov Identifier: NCT00426933 - Completed
Soft Tissue Infections
- Comparative Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia
ClinicalTrials.gov Identifier: NCT00538694 - Completed
Pneumonia, Bacterial
- Study of Cidecin™ (Daptomycin) to Rocephin® (Ceftriaxone) in the Treatment of Moderate to Severe Community-Acquired Acute Bacterial Pneumonia Due to S. Pneumoniae
ClinicalTrials.gov Identifier: NCT00540072 - Completed
Pneumonia, Bacterial
- Daptomycin or Vancomycin in Treating Bacteria in the Blood in Patients With Neutropenia Caused By Chemotherapy
ClinicalTrials.gov Identifier: NCT00296049 - Completed
Infection; Neutropenia; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific
Resources
- Cubicin (Drug Digest)
- Cubicin Consumer Information (U.S. Food and Drug Administration)
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