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Lamivudine and Zidovudine |
3TC and AZT; 3TC and ZDV; Combivir |
Combivir is the brand name for a pharmaceutical treatment for HIV infection. It is a fixed-dose combination of two antiretroviral drugs, lamivudine (also called 3TC, with the brand name Epivir) and zidovudine (also called AZT, with the brand name Retrovir ). The combination of the two drugs has a stronger effect than either drug alone. Both lamivudine and zidovudine are reverse transcriptase inhibitors, which block the action of an enzyme, reverse transcriptase, that the virus requires for r ...
Wikipedia - [full article]
Lamivudine and Zidovudine Clinical Trials
- Comparison of Anti-HIV Drug Combinations to Prevent Mother-to-Child Transmission of HIV
ClinicalTrials.gov Identifier: NCT00086359 - Active, not recruiting
HIV Infections
- Zidovudine and Lamivudine Given Once Versus Twice Daily
ClinicalTrials.gov Identifier: NCT00014014 - Active, not recruiting
HIV Infections
- A Study to Evaluate the Safety and Tolerance of Nelfinavir (NFV) Given with Zidovudine (ZDV) and Lamivudine (3TC) in HIV-Positive Pregnant Women and Their Infants
ClinicalTrials.gov Identifier: NCT00000887 - Active, not recruiting
HIV Infections; Pregnancy
- A Study to Evaluate the Safety and Tolerance of Combination Anti-HIV Drug Therapy (Indinavir, Lamivudine, and Zidovudine) in HIV-Positive Pregnant Women and Their Infants
ClinicalTrials.gov Identifier: NCT00000944 - Active, not recruiting
HIV Infections; Pregnancy
- Safety and Effectiveness of Three Anti-HIV Drugs Combined in One Pill (Trizivir)
ClinicalTrials.gov Identifier: NCT00004981 - Active, not recruiting
HIV Infections
- PI Vs. NNRTI Based Therapy for HIV Advanced Disease
ClinicalTrials.gov Identifier: NCT00162643 - Recruiting
Acquired Immunodeficiency Syndrome
- Four-Drug Combination Therapy with Zidovudine, Lamivudine, 1592U89 (Abacavir), and 141W94 (Amprenavir) in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00006617 - Active, not recruiting
HIV Infections
- Safety and Effectiveness of TRIZIVIR (Abacavir/Lamivudine/Zidovudine) with Efavirenz in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00011895 - Active, not recruiting
HIV Infections
- Study of Anti-HIV Therapy Intensification
ClinicalTrials.gov Identifier: NCT00034086 - Active, not recruiting
HIV Infections
- Safety of and Immune Response to Cyclosporine A in Combination with Abacavir Sulfate, Lamivudine, and Zidovudine and Lopinavir/Ritonavir in Adults with Acute HIV Infection
ClinicalTrials.gov Identifier: NCT00084149 - Active, not recruiting
HIV Infections
- Study of Zidovudine/Lamivudine and Nevirapine for Reduction of Mother-to-Child HIV Transmission During Breastfeeding
ClinicalTrials.gov Identifier: NCT00146380 - Recruiting
HIV Infections
- Comparison of Three Different Initial Treatments Without Protease Inhibitors for HIV Infection
ClinicalTrials.gov Identifier: NCT00013520 - Completed
HIV Infections
- Trial of UK-427,857 in Combination with Zidovudine/Lamivudine versus Efavirenz in Combination with Zidovudine/Lamivudine for the Treatment of HIV-1 Infected Subjects
ClinicalTrials.gov Identifier: NCT00098293 - Active, not recruiting
HIV Infection
- A Comparison of Zidovudine Plus Lamivudine Versus ddI Used Alone or in Combination with Zidovudine in HIV-1 Infected Children
ClinicalTrials.gov Identifier: NCT00001066 - Completed
HIV Infections
- Efavirenz and Lamivudine/Zidovudine for Treatment-Naive HIV Infected Adults and Adolescents in Senegal
ClinicalTrials.gov Identifier: NCT00100568 - Not yet recruiting
HIV Infections
- A Comparison of Lamivudine and Zidovudine, Used Alone and Together, in HIV-Infected Patients Who Have Not Used Zidovudine in the Past
ClinicalTrials.gov Identifier: NCT00002320 - Completed
HIV Infections
- Zidovudine / Lamivudine + Nevirapine Twice Daily, Versus Tenofovir + Lamivudine + Nevirapine Once Daily in ARV-Naive Patients
ClinicalTrials.gov Identifier: NCT00199979 - Recruiting
Hiv Infection With Antiretroviral Therapy Indication; CD4 Below 350/µL or Below 15%
- The Safety and Effectiveness of Lamivudine Plus Stavudine or Zidovudine in HIV-Infected Patients Who Have Taken Zidovudine
ClinicalTrials.gov Identifier: NCT00002371 - Completed
HIV Infections
- A Study to Evaluate the Safety and Tolerance of Stavudine (d4T) in Combination with Lamivudine (3TC) in HIV-Positive Pregnant Women and Their Infants
ClinicalTrials.gov Identifier: NCT00000878 - Active, not recruiting
HIV Infections; Pregnancy
- Potent Antiviral Therapy for Critically Ill HIV Infected Patients Admitted to Intensive Care
ClinicalTrials.gov Identifier: NCT00028327 - Completed
HIV Infections
- The Safety and Effectiveness of Lamivudine Plus Zidovudine, Used with and without 1592U89, in HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002389 - Completed
HIV Infections
- The Safety and Effectiveness of Zidovudine Plus Lamivudine, Used with and without 1592U89, in HIV-1 Infected Children Who Have Taken Anti-HIV-1 Drugs
ClinicalTrials.gov Identifier: NCT00002391 - Completed
HIV Infections
- A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine
ClinicalTrials.gov Identifier: NCT00013897 - Completed
HIV Infections
- Simplified Drug Regimens for HIV Patients in ACTG 388 or Patients Who Responded to A First Potent Combination Regimen
ClinicalTrials.gov Identifier: NCT00014937 - Completed
HIV Infections
- Efavirenz and Lamivudine/Zidovudine for Treatment-Naive HIV Infected People in Wenxi County, Shanxi Province, China
ClinicalTrials.gov Identifier: NCT00100594 - Completed
HIV Infections
- A Study of Three Treatment Combinations Using Zidovudine Plus Lamivudine Plus Indinavir in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001084 - Completed
HIV Infections
- Bioavailability Study of a New Pediatric Formulation of Zidovudine/Lamivudine in Adult Volunteers
ClinicalTrials.gov Identifier: NCT00470041 - Recruiting
Healthy
- A Study of Saquinavir Soft Gelatin Capsules Plus Zidovudine Plus Lamivudine in the Treatment of HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002367 - Completed
HIV Infections
- The Effectiveness of Indinavir Plus Zidovudine Plus Lamivudine in HIV-Infected Patients with No Symptoms of Infection
ClinicalTrials.gov Identifier: NCT00002179 - Completed
HIV Infections
- A Study to Evaluate Various Combinations of Anti-HIV Medications to Treat Early HIV Infection
ClinicalTrials.gov Identifier: NCT00000919 - Completed
HIV Infections
- Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During Pregnancy
ClinicalTrials.gov Identifier: NCT00017719 - Completed
HIV Infections; Pregnancy
- A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment Failure
ClinicalTrials.gov Identifier: NCT00000918 - Completed
HIV Infections
- A Study of Two Anti-HIV Drug Combinations
ClinicalTrials.gov Identifier: NCT00002203 - Completed
HIV Infections
- Antiviral Activity of and Resistance to Lamivudine in Combination with Zidovudine, Stavudine, or Didanosine
ClinicalTrials.gov Identifier: NCT00000838 - Completed
HIV Infections
- A Study of the Safety and Effectiveness of Combination Anti-HIV Therapy in HIV-Infected Adults
ClinicalTrials.gov Identifier: NCT00004585 - Completed
HIV Infections
- Safety and Effectiveness of Ritonavir Plus Lamivudine Plus Zidovudine in HIV-Infected Pregnant Women and Their Babies
ClinicalTrials.gov Identifier: NCT00000888 - Completed
HIV Infections; Pregnancy
- Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected with HIV
ClinicalTrials.gov Identifier: NCT00001119 - Completed
HIV Infections
- Virologic and Immunologic Activity of Continued Lamivudine (3TC) vs Delavirdine (DLV) in Combination with Indinavir (IDV) and Zidovudine (ZDV) or Stavudine (d4T) in 3TC-Experienced Subjects
ClinicalTrials.gov Identifier: NCT00000882 - Completed
HIV Infections
- Effectiveness of a New Anti-HIV Drug (AG1549) Plus Viracept (Nelfinavir) Plus Combivir (Zidovudine/Lamivudine) in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00004999 - Suspended
HIV Infections
- Addition of Efavirenz or Nelfinavir to a Lamivudine/Zidovudine/Indinavir HIV Treatment Regimen
ClinicalTrials.gov Identifier: NCT00000903 - Completed
HIV Infections
- A Study of Indinavir Sulfate Plus Zidovudine (AZT) Plus Lamivudine in HIV-Infected Patients Who Have Taken AZT for Six or More Months
ClinicalTrials.gov Identifier: NCT00000841 - Completed
HIV Infections
- NRTI-Sparing Pilot Study
ClinicalTrials.gov Identifier: NCT00143689 - Active, not recruiting
HIV; Mitochondrial Toxicity
- Treatment with Combinations of Several Antiviral Drugs in Infants and Young Children with HIV Infection
ClinicalTrials.gov Identifier: NCT00000872 - Active, not recruiting
HIV Infections
- Treatment with Interleukin-2 (IL-2) Plus Combination Anti-HIV-Drug Therapy (HAART) for Patients Formerly in ACTG 328
ClinicalTrials.gov Identifier: NCT00000923 - Active, not recruiting
HIV Infections
- Lopinavir/Ritonavir in Combination with Saquinavir Mesylate or Lamivudine/Zidovudine to Explore Metabolic Toxicities in Antiretroviral HIV-Infected Subjects
ClinicalTrials.gov Identifier: NCT00043953 - Completed
HIV Infections
- A Phase II Open-Label Exploratory Study of Saquinavir + Zidovudine + Lamivudine in HIV Infected Patients
ClinicalTrials.gov Identifier: NCT00002190 - Completed
HIV Infections
- Fortovase (Saquinavir) Given with Low-Dose Ritonavir, Zidovudine, and Lamivudine to HIV-Positive Pregnant Women During and After Pregnancy and to Their Newborns
ClinicalTrials.gov Identifier: NCT00000920 - Completed
HIV Infections; Pregnancy
- The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined with Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002379 - Completed
HIV Infections
- The Effectiveness of Ritonavir Plus Zidovudine Plus Lamivudine in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001075 - Completed
HIV Infections
- Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at Birth
ClinicalTrials.gov Identifier: NCT00102960 - Active, not recruiting
HIV Infections
- Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV Infection
ClinicalTrials.gov Identifier: NCT00001644 - Active, not recruiting
HIV Infection
- Comparing the Safety, Effectiveness, and Tolerability of Three Anti-HIV Drug Regimens for Treatment-Naive Patients
ClinicalTrials.gov Identifier: NCT00050895 - Active, not recruiting
HIV Infections
- A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy
ClinicalTrials.gov Identifier: NCT00102206 - Active, not recruiting
HIV Infections
- A Study on the Management of Combination Anti-HIV Drug Therapy in HIV-Positive Children with Prior Treatment
ClinicalTrials.gov Identifier: NCT00000902 - Active, not recruiting
HIV Infections
- Once-Daily PI/NNRTI Therapy Combinations for Treatment Naive, HIV Infected Patients in Resource-limited Conditions
ClinicalTrials.gov Identifier: NCT00084136 - Active, not recruiting
HIV Infections
- A Study of Ritonavir (an Anti-HIV Drug) in HIV-Positive Infants and Children
ClinicalTrials.gov Identifier: NCT00000952 - Active, not recruiting
HIV Infections
- Effectiveness of Treating HIV-Positive Patients with an HIV Vaccine (Remune)
ClinicalTrials.gov Identifier: NCT00005002 - Active, not recruiting
HIV Infections
- Treatment with Nelfinavir or Efavirenz of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00005000 - Active, not recruiting
HIV Infections
- 3TC (Lamivudine; GR109714X) Open-Label Program
ClinicalTrials.gov Identifier: NCT00002108 - Completed
HIV Infections
- A Study of the Safety and Effectiveness of Hydroxyurea in Patients on Potent Antiretroviral Therapy and Who Have Less Than 200 Copies/ml of HIV RNA in Their Blood
ClinicalTrials.gov Identifier: NCT00000916 - Terminated
HIV Infections
- Study of Treatment of Antiretroviral-Naive, HIV-1-Infected Patients Comparing Tenofovir Disoproxil Fumarate Administered in Combination with Lamivudine and Efavirenz Vs. Stavudine, Lamivudine and Efavirenz.
ClinicalTrials.gov Identifier: NCT00158821 - Active, not recruiting
HIV-1
- Effectiveness of Adding Interleukin-2 to Anti-HIV Drugs in Patients Recently Infected with HIV
ClinicalTrials.gov Identifier: NCT00006441 - Recruiting
HIV Infections
- A Study of 141W94 Used Alone or in Combination with Zidovudine Plus 3TC in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001085 - Completed
HIV Infections
- A Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00005106 - Completed
HIV Infections
- Once a Day (QD) - Twice a Day (BID) Clinical Trial: Didanosine, Lamivudine and Efavirenz Versus Zidovudine, Lamivudine and Efavirenz in the Starting Treatment of HIV
ClinicalTrials.gov Identifier: NCT00256828 - Completed
HIV Infections
- When to Start Anti-HIV Drugs in Children Infected With HIV
ClinicalTrials.gov Identifier: NCT00234091 - Recruiting
HIV Infections
- Early Versus Standard Start of Anti-HIV Therapy for Treatment-Naive Adults in Haiti
ClinicalTrials.gov Identifier: NCT00120510 - Recruiting
HIV Infections; Tuberculosis
- MEDICLAS Study (Metabolic Effects of Different Classes of AntiretroviralS)
ClinicalTrials.gov Identifier: NCT00122226 - Active, not recruiting
HIV Infections; HIV-Associated Lipodystrophy Syndrome
- A Study of Increased Lactic Acid and Abnormal Fat Distribution in HIV-Positive Patients
ClinicalTrials.gov Identifier: NCT00005764 - Completed
HIV Infections; Lipodystrophy
- Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women who Take Nevirapine During Pregnancy
ClinicalTrials.gov Identifier: NCT00099632 - Recruiting
HIV Infections
- Comparing the Effectiveness of a Triple Nucleoside Reverse Transcriptase Inhibitor Regimen Versus a Protease Inhibitor-Based Regimen In the Prevention of Mother-to-Child Transmission of HIV
ClinicalTrials.gov Identifier: NCT00270296 - Recruiting
HIV Infections
- Tenofovir Disoproxil Fumarate (DF)/Emtricitabine/Efavirenz Versus Combivir/Efavirenz in Antiretroviral-Naive HIV-1 Infected Subjects
ClinicalTrials.gov Identifier: NCT00112047 - Active, not recruiting
HIV Infections
- Preventing Sexual Transmission of HIV With Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00074581 - Completed
HIV Infections; HIV Seronegativity
- Anti-HIV Drugs for Ugandan Patients With HIV and Tuberculosis
ClinicalTrials.gov Identifier: NCT00078247 - Recruiting
HIV Infections; Tuberculosis
- Safety of VIRACEPT® 625 Mg During Pregnancy
ClinicalTrials.gov Identifier: NCT00246610 - Recruiting
HIV Infections; Pregnancy
- A Treatment IND for Retrovir Brand Zidovudine (AZT) Therapy of Pediatric Patients With HIV Disease
ClinicalTrials.gov Identifier: NCT00000662 - Active, not recruiting
HIV Infections
- A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 mg q 8 h Versus 1,200 mg q 12 h in Combination with Zidovudine and 3TC
ClinicalTrials.gov Identifier: NCT00002208 - Completed
HIV Infections
- Safety and Effectiveness of Giving Indinavir Plus Stavudine Plus Lamivudine to HIV-Infected Children
ClinicalTrials.gov Identifier: NCT00000901 - Active, not recruiting
HIV Infections
- A Comparison of Zidovudine (AZT) Used Alone or in Combination with Didanosine (ddI) or Dideoxycytidine (ddC) in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00001022 - Active, not recruiting
HIV Infections
- A Study to Test the Safety, Tolerance, and Metabolism of Abacavir (1592U89, ABC) With Standard Zidovudine (ZDV) Therapy in Newborn Infants Born to HIV-1 Infected Women
ClinicalTrials.gov Identifier: NCT00000864 - Active, not recruiting
HIV Infections
- A Double-Blind, Randomized, Dose Response Study of Three Doses of Delavirdine Mesylate (U-90152S) in Combination with Zidovudine (ZDV) versus ZDV alone in HIV-1 Infected Individuals with CD4 Counts of 200-500mm3
ClinicalTrials.gov Identifier: NCT00002124 - Completed
HIV Infections
- Safety and Effectiveness of Lamivudine When Given Once a Day versus Twice a Day in Combination with Other Anti-HIV Drugs in HIV-Infected Adults Who Have Never Received Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00004852 - Completed
HIV Infections
- Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
ClinicalTrials.gov Identifier: NCT00002451 - Active, not recruiting
HIV Infections
- Switching from Zidovudine to an NNRTI or Lopinavir/Ritonavir in Patients Treated with Zidovudine/ Lamivudine/Abacavir.
ClinicalTrials.gov Identifier: NCT00139178 - Completed
HIV associated lipodystrophy syndrome.; HIV; Hypercholesterolemia; Lipoatrophy
- A Study of Zidovudine During Labor and Delivery in HIV-Infected Pregnant Women
ClinicalTrials.gov Identifier: NCT00000862 - Active, not recruiting
HIV Infections; Pregnancy
- Switching Study From Lamivudine to Clevudine Versus Continued Lamivudine in the Chronic Hepatitis B Patients
ClinicalTrials.gov Identifier: NCT00558493 - Recruiting
Chronic Hepatitis B
- Comparison of GW433908/Ritonavir to Nelfinavir When Used with Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs
ClinicalTrials.gov Identifier: NCT00009061 - Active, not recruiting
HIV Infections
- A Phase I Study to Evaluate the Safety and Toxicity of the Combination of Zidovudine and 2',3'-Dideoxyinosine (Didanosine) in Children With HIV Infection
ClinicalTrials.gov Identifier: NCT00000652 - Active, not recruiting
HIV Infections
- Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission
ClinicalTrials.gov Identifier: NCT00099359 - Recruiting
Disease Transmission, Vertical; Vertical Transmission; HIV Infections
- Lamivudine and Therapeutic Vaccine Evaluation in Senegalese Patients with Chronic Hepatitis B Infection
ClinicalTrials.gov Identifier: NCT00120796 - Recruiting
Hepatitis B
- An Open-Label Study of Nevirapine Plus Zidovudine (ZDV) and 3TC Treatment in Women Who Have Previously Received a Nevirapine Regimen for the Prevention of Mother to Child Transmission (pMTCT) of HIV-1.
ClinicalTrials.gov Identifier: NCT00144157 - Active, not recruiting
Acquired Immunodeficiency Syndrome
- A Six-Month Safety and Antiviral Study in HIV-1 Seropositive, AZT-Experienced Patients With CD4 Counts Less Than or Equal to 50 Cells/mm3 to Evaluate MK-639 Alone Versus Zidovudine (AZT) and 3TC Versus the Combination of MK-639 With AZT/3TC
ClinicalTrials.gov Identifier: NCT00002155 - Completed
HIV Infections
- Telbivudine versus Lamivudine in Adults with Decompensated Chronic Hepatitis B and Evidence of Cirrhosis
ClinicalTrials.gov Identifier: NCT00076336 - Active, not recruiting
Hepatitis; Hepatitis B, Chronic; Cirrhosis
- Efavirenz Or Atazanazir/Ritonavir Given with Emtricitabine/Tenofovir Disoproxil Fumarate Or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults
ClinicalTrials.gov Identifier: NCT00118898 - Active, not recruiting
HIV Infections
- Study Comparing the Safety of Switching From Lamivudine to Adefovir Dipivoxil Versus Overlapping Lamivudine and Adefovir Before Adefovir Dipivoxil Monotherapy in Patients With Chronic Hepatitis B
ClinicalTrials.gov Identifier: NCT00307242 - Recruiting
Chronic Hepatitis B
- Combination Chemotherapy Followed By Antiviral Therapy and Interferon alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma
ClinicalTrials.gov Identifier: NCT00041327 - Active, not recruiting
stage I adult T-cell leukemia/lymphoma; stage II adult T-cell leukemia/lymphoma; stage III adult T-cell leukemia/lymphoma; ...
- A Phase III Randomized, Double-Blind, Controlled Study of the Use of Anti-HIV Immune Serum Globulin (HIVIG) for the Prevention of Maternal-Fetal HIV Transmission in Pregnant Women and Newborns Receiving Zidovudine (AZT)
ClinicalTrials.gov Identifier: NCT00000751 - Active, not recruiting
HIV Infections; Pregnancy
- Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy
ClinicalTrials.gov Identifier: NCT00000831 - Completed
HIV Infections
- A Study of Retrovir and Epivir Alone or in Combination with 141W94 in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00002195 - Completed
HIV Infections
- Zidovudine Plus Lamivudine in HTLV-I-Associated Myelopathy: a Randomised Trial
ClinicalTrials.gov Identifier: NCT00272480 - Completed
HTLV-I-Associated Myelopathy
Resources
- Combivir (Drug Digest)
- Lamivudine and Zidovudine (Drug Digest)
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