Choline Salicylate and Magnesium Salicylate |
CMT; Tricosal; Trilisate |
Clinical Trial: Choline Quantification in Breast Cancer by MRS
This study is not yet open for patient recruitment.
Verified by Norwegian University of Science and Technology September 2005
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Purpose
Cholin has been found in increased concentration in breast cancer patients. Hypothesis: The choline signal as observed by MRS is sensitive to treatment, and a positive response to treatment will give a reduction in choline concentration.
The purpose of this study is to establish methods for quantification of choline in breastcancer by MRS
| Condition |
|---|
| Breast Neoplasms |
MedlinePlus related topics: Breast Cancer
Genetics Home Reference related topics: breast cancer
Study Type: Observational
Study Design: Screening, Cross-Sectional, Defined Population, Prospective Study
Expected Total Enrollment: 10
Study start: October 2005; Expected completion: December 2008
Last follow-up: December 2008; Data entry closure: December 2008
- Establishment of new MRS sequence for choline quantification of choline. This sequence is choline-selective, and signals from water and lipids are suppressed simultaneously.
- Compare to different methods for choline quantifiaction. The first method is quantification through an external phantom standard, containing a known concentration of choline. The other method is based on the utilisation of internal water signal as a reference.
Both calculations can be performed from the same MR exam. Ten patients will be included in the study.
Eligibility
Inclusion Criteria:
- breast cancer
Exclusion Criteria:
-
Location and Contact Information
Tone Bathen, PhD, Principal Investigator, NTNU, Faculty of medicine,
More Information
Last Updated: September 19, 2005
Record first received: September 16, 2005
ClinicalTrials.gov Identifier: NCT00201487
Health Authority: Norway: Norwegian Social Science Data Services
ClinicalTrials.gov processed this record on 2005-09-20
Resources
- Choline Salicylate and Magnesium Salicylate (Drug Digest)
- CMT (Drug Digest)

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