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Effects of Pretreatment With Ibuprofen in Post- ECT Headache - Article


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Clinical Trial: Effects of Pretreatment With Ibuprofen in Post- ECT Headache

This study is not yet open for patient recruitment.
Verified by Norwegian University of Science and Technology November 2005

Sponsored by: Norwegian University of Science and Technology
Information provided by: Norwegian University of Science and Technology
ClinicalTrials.gov Identifier: NCT00258791

Purpose

The purpose of the study is to determine wether ibuprofen reduce post-ECT headache or reduce its severity.
Condition Intervention
Mental Disorders
  Drug: Ibuprofen

MedlinePlus related topics:  Mental Health

Study Type: Interventional
Study Design: Treatment, Randomized, Double-Blind, Placebo Control, Crossover Assignment, Safety/Efficacy Study

Further study details as provided by Norwegian University of Science and Technology:
Primary Outcomes: Score on depression rating scale prior to and after ECT treatment; score on headache prior to and after ECT treatment
Secondary Outcomes: ECT paramenters
Expected Total Enrollment:  30

Study start: March 2006;  Expected completion: December 2007
Last follow-up: June 2007;  Data entry closure: December 2007

The aim of the study is to compare the severity of headache between patients who are receiving ibuprofen prior to ECT treatment with patients receiving placebo prior to ECT treatment.

Patients will be randomly assigned to receive either 600 mg ibuprofen 90 min prior to treatment or placebo orally, blinded to patient, physician and treatment team.

Patients will be asked about their headache with a visual analogue scale (VAS) 2 hours prior to and within 2 hours after treatment, 2-month, 6- month and 1 year follow-up [5].

Eligibility

Ages Eligible for Study:  18 Years and above,  Genders Eligible for Study:  Both
Criteria

Inclusion Criteria:

  • Patients receiving ECT

Exclusion Criteria:

  • Pregnancy, contraindications to ibuprofen

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier  NCT00258791

Lindy Jarosch-von Schweder, MD      47 73864533    lindy.jarosch@ntnu.no

Norway
      Østmarka Psychiatric Department, St. OLavs Hospital, University Hospital of Trondheim, Trondheim,  Norway
Lindy Jarosch-von Schweder, MD  47 73864533    lindy.jarosch@ntnu.no 
Olav Morten Linaker, MD PhD,  Principal Investigator

Study chairs or principal investigators

Olav Morten Linaker, MD PhD,  Principal Investigator,  Norwegian University of Science and Technology   

More Information

Study ID Numbers:  LVS-2005
Last Updated:  December 8, 2005
Record first received:  November 24, 2005
ClinicalTrials.gov Identifier:  NCT00258791
Health Authority: Norway: Norwegian Social Science Data Services
ClinicalTrials.gov processed this record on 2006-01-10


Source: ClinicalTrials.gov
Cache Date: January 11, 2006

Resources



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Page Updated: June 1, 2005
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