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Lactulose |
Cephulac; Cholac; Chronulac; Constilac; Constulose; Duphalac; Enulose |
Lactulose Systematic (IUPAC) name 4-O-(beta)-D-Galactopyranosyl-D-fructofuranose Identifiers CAS number 4618-18-2 ATC code A06AD11 PubChem 11333 DrugBank APRD01063 Chemical data Formula C12H22O11 Mol. weight 342.296 g/mol Pharmacokinetic data Bioavailability Poorly absorbed Metabolism 100% in colon by enteric bacteria Half life 1.7-2 hours Excretion rectal Therapeutic considerations Pregnancy cat. ? Legal status OTC (UK) Routes oral L ...
Wikipedia - [full article]
Lactulose Clinical Trials
- Trial to Evaluate Effect of Lactulose on Hard Stools in Patients with Hemorrhoids or Anal Fissures
ClinicalTrials.gov Identifier: NCT00160290 - Active, not recruiting
hemorrhoids; anal fissures
- Lactulose for the Prevention of Nosocomial Infections in Children
ClinicalTrials.gov Identifier: NCT00273949 - Recruiting
Nosocomial Infection
- Safety and Efficacy of AST-120 Compared to Lactulose in Patients With Hepatic Encephalopathy
ClinicalTrials.gov Identifier: NCT00558038 - Recruiting
Hepatic Encephalopathy
- Lactulose for the Prevention of Hepatic Encephalopathy in Cirrhotic Patients With Upper Gastrointestinal Hemorrhage
ClinicalTrials.gov Identifier: NCT00553423 - Recruiting
Hepatocerebral Encephalopathy; Portal-Systemic Encephalopathy; Encephalopathy, Hepatic; Encephalopathy, Hepatocerebral
- Phase II Study of Lactulose and Circadian Rhythms in Patients with Cirrhosis
ClinicalTrials.gov Identifier: NCT00004796 - Completed
Portal Hypertension; Hepatic Encephalopathy; Cirrhosis
- Study to Investigate if Adding Lactulose to Vitamin D and Calcium Has an Effect on the Preservation of Bone in Postmenopausal Women
ClinicalTrials.gov Identifier: NCT00160264 - Completed
Osteopenia
- Effect of Lactulose on Minimal Hepatic Encephalopathy and Health-Related Quality of Life
ClinicalTrials.gov Identifier: NCT00375375 - Completed
Minimal Hepatic Encephalopathy; Hepatic Encephalopathy
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