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Calcitriol |
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Calcitriol Systematic (IUPAC) name (1R,3S)- 5-[2-[(1R,3aR,7aS)-1- [(2R)-6-hydroxy-6-methyl-heptan-2-yl]- 7a-methyl-2,3,3a,5,6,7-hexahydro-1H- inden-4-ylidene]ethylidene]- 4-methylidene-cyclohexane-1,3-diol Identifiers CAS number 32222-06-3 ATC code A11CC04 D05AX03 PubChem 134070 DrugBank APRD00246 Chemical data Formula C27H44O3 Mol. weight 416.64 g.mol-1 Pharmacokinetic data Bioavailability ? Metabolism Renal Half life 5–8 hours Excretion Re ...
Wikipedia - [full article]
Calcitriol Clinical Trials
- ASCENT: Androgen Independent Prostate Cancer Study of Calcitriol Enhancing Taxotere
ClinicalTrials.gov Identifier: NCT00043576 - Active, not recruiting
Prostate Cancer
- Study of High-dose Pulse Administration DN-101 (Calcitriol) in Patients with Myelodysplastic Syndrome (MDS)
ClinicalTrials.gov Identifier: NCT00057031 - Active, not recruiting
Myelodysplastic Syndrome
- Calcitriol Plus Carboplatin in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00008086 - Active, not recruiting
Brain Tumor; Genetic Condition; Solid Tumor
- Calcitriol in Treating Patients With a Rising PSA Level Following Treatment for Prostate Cancer
ClinicalTrials.gov Identifier: NCT00004043 - Active, not recruiting
adenocarcinoma of the prostate; recurrent prostate cancer; Quality of Life
- Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer Who Have Undergone Surgery or Radiation Therapy
ClinicalTrials.gov Identifier: NCT00054522 - Active, not recruiting
adenocarcinoma of the prostate; recurrent prostate cancer
- Study of Topical Calcitriol or Oral Calcitriol in Patients with Psoriasis
ClinicalTrials.gov Identifier: NCT00004468 - Completed
Psoriasis
- Calcitriol in Preventing Prostate Cancer in Patients with Prostatic Intraepithelial Neoplasia
ClinicalTrials.gov Identifier: NCT00118066 - Recruiting
Prostate Cancer; Precancerous Condition
- Calcitriol and Gefitinib With or Without Dexamethasone in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00084708 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Calcitriol and Carboplatin in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Hormone Therapy
ClinicalTrials.gov Identifier: NCT00017576 - Active, not recruiting
stage IV prostate cancer; adenocarcinoma of the prostate; recurrent prostate cancer
- Calcitriol and Dexamethasone in Patients With Myelodysplastic Syndromes
ClinicalTrials.gov Identifier: NCT00030069 - Recruiting
Myelodysplastic Syndromes
- Calcitriol Plus Dexamethasone in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
ClinicalTrials.gov Identifier: NCT00010231 - Active, not recruiting
stage III prostate cancer; stage IV prostate cancer; adenocarcinoma of the prostate; recurrent prostate cancer
- Calcitriol and Zoledronate in Treating Patients With Progressive Prostate Cancer
ClinicalTrials.gov Identifier: NCT00004928 - Active, not recruiting
stage II prostate cancer; stage III prostate cancer; stage IV prostate cancer; stage I prostate cancer; adenocarcinoma of the prostate; ...
- Calcitriol and Docetaxel in Treating Patients With Metastatic or Locally Advanced Pancreatic Cancer
ClinicalTrials.gov Identifier: NCT00238199 - Active, not recruiting
Pancreatic Cancer
- Calcitriol and Dexamethasone Before Radical Prostatectomy in Treating Patients With Localized Adenocarcinoma (Cancer) of the Prostate
ClinicalTrials.gov Identifier: NCT00084864 - Recruiting
adenocarcinoma of the prostate; stage II prostate cancer; stage III prostate cancer
- Calcitriol, Mitoxantrone, and Prednisone in Treating Patients With Metastatic Prostate Cancer
ClinicalTrials.gov Identifier: NCT00182741 - Active, not recruiting
Prostate Cancer
- Study of DN-101 (Calcitriol) and Docetaxel in Subjects Previously Enrolled in Studies DN101-002 or DN101-004
ClinicalTrials.gov Identifier: NCT00285675 - Active, not recruiting
Androgen Independent Prostate Cancer (AIPC); Non Small Cell Lung Cancer (NSCLC)
- Effects of Calcitriol Versus PTH Replacement Therapy in Patients With Hypoparathyroidism
ClinicalTrials.gov Identifier: NCT00395538 - Recruiting
Hypoparathyroidism
- Calcitriol in the Treatment of IgA Nephropathy
ClinicalTrials.gov Identifier: NCT00319761 - Active, not recruiting
IGA Nephropathy
- Study of Topical Calcitriol in Children With Psoriasis
ClinicalTrials.gov Identifier: NCT00006275 - Completed
Psoriasis
- Calcitriol or Placebo in Men for Prostate Cancer Active Surveillance
ClinicalTrials.gov Identifier: NCT00482157 - Not yet recruiting
Prostatic Neoplasms
- PK and PD of Calcitriol BID Topical Treatment in Adolescents With Plaque Psoriasis
ClinicalTrials.gov Identifier: NCT00419666 - Recruiting
Chronic Plaque Psoriasis
- Calcitriol, Cisplatin, and Docetaxel in Treating Patients With Advanced Non-Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00470431 - Recruiting
Lung Cancer
- A Phase II Trial of Calcitriol and Naproxen in Patients With Recurrent Prostate Cancer
ClinicalTrials.gov Identifier: NCT00383487 - Recruiting
Prostate Cancer
- Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
ClinicalTrials.gov Identifier: NCT00524589 - Recruiting
Prostate Cancer
- Calcitriol, Ketoconazole, and Hydrocortisone in Treating Patients With Advanced or Recurrent Prostate Cancer
ClinicalTrials.gov Identifier: NCT00536991 - Recruiting
Prostate Cancer
- Calcitriol Plus Paclitaxel in Treating Patients With Advanced Solid Tumors
ClinicalTrials.gov Identifier: NCT00009802 - Completed
unspecified adult solid tumor, protocol specific
- The Efficacy and Safety of Calcitriol for the Treatment of Lupus Nephritis and Persistent Proteinuria
ClinicalTrials.gov Identifier: NCT00508898 - Not yet recruiting
Systemic Lupus Erythematosus; Nephritis; Proteinuria
- Calcitriol, Ketoconazole, and Dexamethasone in Treating Patients With Metastatic or Unresectable Solid Tumors
ClinicalTrials.gov Identifier: NCT00238225 - Completed
Unspecified Adult Solid Tumor, Protocol Specific
- A New Formulation of Calcitriol (DN-101) in Patients with Advanced Malignancies
ClinicalTrials.gov Identifier: NCT00055263 - Completed
Neoplasms
- Osteoporosis Prevention After Heart Transplant
ClinicalTrials.gov Identifier: NCT00000412 - Completed
Osteoporosis; Cardiac transplantation
- Calcitriol and Temozolomide in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00301067 - Suspended
Intraocular Melanoma; Melanoma (Skin)
- Phase III Randomized Study of Interferon Gamma in Children With Severe, Congenital Osteopetrosis
ClinicalTrials.gov Identifier: NCT00004402 - Completed
Osteopetrosis
- Study of DN101 and Taxotere in Patients with Advanced Non-Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00066885 - Completed
Carcinoma, Non-Small-Cell Lung
- Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance Dialysis
ClinicalTrials.gov Identifier: NCT00004340 - Completed
Renal Osteodystrophy; End Stage Renal Disease
- DN-101 in Combination With Docetaxel in Androgen-Independent Prostate Cancer (AIPC) (ASCENT-2)
ClinicalTrials.gov Identifier: NCT00273338 - Terminated
Prostate Cancer
Resources
- Calcitriol (Drug Digest)
- Rocaltrol (Drug Digest)
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