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Bupropion |
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Bupropion Systematic (IUPAC) name (±)-1-(3-chlorophenyl)- 2-[(1,1-dimethylethyl)amino]- 1-propanone Identifiers CAS number 34841-39-9 ATC code N07BA02 PubChem 444 DrugBank APRD00621 Chemical data Formula C13H18NClO Mol. weight 239.74 Pharmacokinetic data Bioavailability 5-20% in animals; no studies in humans Metabolism Hepatic Half life 20 hours Excretion Urine (87%), feces (10%) Therapeutic considerations Pregnancy cat. B (USA) Legal statu ...
Wikipedia - [full article]
Bupropion Clinical Trials
- Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation
ClinicalTrials.gov Identifier: NCT00419731 - Recruiting
Tobacco Use Disorder
- Pilot Study of Bupropion for Smoking Cessation in Postpartum Non-Breastfeeding Women
ClinicalTrials.gov Identifier: NCT00119210 - Active, not recruiting
Tobacco Use Disorder
- Bupropion and Weight Control for Smoking Cessation - 1
ClinicalTrials.gov Identifier: NCT00006170 - Active, not recruiting
Tobacco Use Disorder
- Framing Messages for Smoking Cessation with Bupropion - 6
ClinicalTrials.gov Identifier: NCT00104598 - Active, not recruiting
Tobacco Use Disorder
- Bupropion as a Smoking Cessation Aid in Alcoholics
ClinicalTrials.gov Identifier: NCT00044434 - Active, not recruiting
Alcoholism; Smoking
- Assessment of Potential Interactions between Methamphetamine and Bupropion - 1
ClinicalTrials.gov Identifier: NCT00040040 - Active, not recruiting
Amphetamine-Related Disorders
- Bupropion for the Treatment of Methamphetamine Dependence - 1
ClinicalTrials.gov Identifier: NCT00069251 - Active, not recruiting
Amphetamine-Related Disorders
- Effectiveness of Bupropion Combined with Behavioral Thearpy for Treating Methamphetamine Dependence - 2
ClinicalTrials.gov Identifier: NCT00135785 - Recruiting
methamphetamine
- Effects of a Voucher Incentive Program and a Pharmacological Intervention (Bupropion) on Smoking in People with Schizophrenia. - 1
ClinicalTrials.gov Identifier: NCT00136760 - Recruiting
Tobacco Use Disorder
- Effectiveness of Bupropion in Treating Marijuana Dependent Individuals - 1
ClinicalTrials.gov Identifier: NCT00142870 - Active, not recruiting
Marijuana Abuse; Substance-Related Disorders
- Effectiveness of Bupropion for Treating Nicotine Dependence in Young People - 1
ClinicalTrials.gov Identifier: NCT00129272 - Recruiting
Tobacco Use Cessation; Tobacco Use Disorder
- Bupropion and Counseling With or Without Contingency Management to Enhance Smoking Cessation in Treating Cancer Survivors Who Continue to Smoke
ClinicalTrials.gov Identifier: NCT00079469 - Active, not recruiting
unspecified adult solid tumor, protocol specific
- Smoking Cessation Treatment - 1
ClinicalTrials.gov Identifier: NCT00110825 - Active, not recruiting
Behavior Therapy; Bupropion; Tobacco Use Disorder; nicotine transdermal system
- A Comparison of Bupropion SR and Placebo for Smoking Cessation
ClinicalTrials.gov Identifier: NCT00176449 - Active, not recruiting
Tobacco Use Disorder
- Nicotine Patch and Bupropion to Reduce Smoking Rates in Younger, Low-Income, and Minority Individuals
ClinicalTrials.gov Identifier: NCT00308763 - Active, not recruiting
Tobacco Use Disorder
- Effectiveness of Nefazodone and Bupropion in Treating Marijuana Dependent Individuals
ClinicalTrials.gov Identifier: NCT00249509 - Active, not recruiting
Marijuana Abuse
- Risperidone Vs. Bupropion ER Augmentation of SSRIs in Treatment-Resistant Depression
ClinicalTrials.gov Identifier: NCT00179244 - Active, not recruiting
Unipolar Depression
- Bupropion For Reducing High-Risk Behaviors in Depressed Men Who Have Sex With Men (MSM)
ClinicalTrials.gov Identifier: NCT00285584 - Active, not recruiting
HIV Infections; Depression
- A Study of Naltrexone SR/Bupropion SR and Placebo in Obese Subjects Participating in a Behavior Modification Program
ClinicalTrials.gov Identifier: NCT00456521 - Active, not recruiting
Obesity
- Bupropion for Hospital-Based Smoking Cessation
ClinicalTrials.gov Identifier: NCT00261170 - Active, not recruiting
Smoking
- Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who Smoke
ClinicalTrials.gov Identifier: NCT00307203 - Active, not recruiting
Tobacco-Use Disorder; Schizophrenia; Psychotic Disorders
- Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking
ClinicalTrials.gov Identifier: NCT00248118 - Recruiting
Tobacco Dependence
- Bupropion With Telephone-Based Counseling and/or Internet-Based Counseling in Helping Adults Stop Smoking
ClinicalTrials.gov Identifier: NCT00301145 - Active, not recruiting
Unspecified Adult Solid Tumor, Protocol Specific
- Drug Treatment for Pathological Gambling
ClinicalTrials.gov Identifier: NCT00055393 - Active, not recruiting
Gambling
- Effect of Combined Pharmacotherapy/Behavioral Treatment on Smoking Cessation For Methadone Maintenance Therapy Patients - 2
ClinicalTrials.gov Identifier: NCT00060814 - Active, not recruiting
Tobacco Use Disorder
- Paroxetine Versus Bupropion for Treating People With High-Risk Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00429169 - Recruiting
Depression
- Effect of Ethanol and Genetic Polymorphisms on Bupropion Metabolism
ClinicalTrials.gov Identifier: NCT00330434 - Recruiting
Alcohol Drinking; Depression; Smoking Cessation; Attention Deficit Disorder
- Effectiveness of Bupropion Used in Combination with the Nicotine Replacement Patch and Cognitive Behavioral Therapy for Treating Nicotine Dependent Individuals - 1
ClinicalTrials.gov Identifier: NCT00142831 - Active, not recruiting
Tobacco Use Disorder
- ISTAPS: A Stepped Primary Care Smoking Cessation Intervention
ClinicalTrials.gov Identifier: NCT00125905 - Active, not recruiting
Smoking cessation
- Effect of Bupropion on Smoking Behavior in People With Schizophrenia Who Smoke
ClinicalTrials.gov Identifier: NCT00218231 - Recruiting
Schizophrenia
- A Study of Two Doses of Naltrexone SR/Bupropion SR and Placebo in Obese Subjects
ClinicalTrials.gov Identifier: NCT00532779 - Recruiting
Obesity
- Dopamine Reuptake Inhibitors of Cocaine Abuse - 1
ClinicalTrials.gov Identifier: NCT00000276 - Active, not recruiting
Cocaine-Related Disorders
- Effectiveness of Bupropion for Smokers Recovering From Alcohol Dependence
ClinicalTrials.gov Identifier: NCT00304707 - Recruiting
Smoking Cessation; Alcohol-Related Disorders
- Tobacco Dependence: Treatment and Outcomes Project 3 Pharmacotherapies: Effectiveness in Primary Care - 2
ClinicalTrials.gov Identifier: NCT00106873 - Recruiting
nicotine
- Bupropion in the Treatment of Methamphetamine Dependence
ClinicalTrials.gov Identifier: NCT00572234 - Recruiting
Methamphetamine Use Disorder
- Research Evaluating the Value of Augmenting Medication with Psychotherapy (REVAMP)
ClinicalTrials.gov Identifier: NCT00057551 - Active, not recruiting
Depression; Depressive Disorder
- Hormone and Sleep Response to Antidepressant Treatment in Adolescents and Adults with Depression
ClinicalTrials.gov Identifier: NCT00106197 - Recruiting
Depression
- A Study of Aripiprazole in Patients with Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00105196 - Active, not recruiting
Major Depressive Disorder
- Maintaining Abstinence in Chronic Cigarette Smokers - 1
ClinicalTrials.gov Identifier: NCT00087880 - Recruiting
Tobacco Use Disorder
- A Safety and Efficacy Study Comparing Naltrexone SR/Bupropion SR and Placebo in Obese Type 2 Diabetics
ClinicalTrials.gov Identifier: NCT00474630 - Recruiting
Obesity; Diabetes Mellitus, Type 2
- Fluoxetine and Bupropion to Treat Patients With Depression and Alcoholism
ClinicalTrials.gov Identifier: NCT00449007 - Recruiting
Depression; Alcoholism; Suicidal Behavior
- Maintenance Treatment for Abstinent Smokers - 1
ClinicalTrials.gov Identifier: NCT00063323 - Recruiting
Tobacco Use Disorder
- A Safety and Efficacy Study of Naltrexone SR/Bupropion SR in Obesity
ClinicalTrials.gov Identifier: NCT00567255 - Recruiting
Obesity
- A Study of Naltrexone SR/ Bupropion SR in Overweight and Obese Subjects Who Are Nicotine-Dependent
ClinicalTrials.gov Identifier: NCT00563563 - Recruiting
Nicotine Dependence; Overweight; Obesity
- Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 2: Do Varenicline (Chantix) and Bupropion (Zyban) Change Alcohol Drinking?
ClinicalTrials.gov Identifier: NCT00580645 - Recruiting
Alcohol Drinking
- Bupropion in Helping Adults Stop Smoking
ClinicalTrials.gov Identifier: NCT00534001 - Recruiting
Bladder Cancer; Cervical Cancer; Esophageal Cancer; Gastric Cancer; Head and Neck Cancer; Kidney Cancer; Leukemia; Liver Cancer; Lung Cancer; Pancreatic Cancer; Tobacco Use Disorder
- Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1
ClinicalTrials.gov Identifier: NCT00124683 - Completed
Tobacco Use Cessation; Tobacco Use Disorder; Schizophrenia
- The Effect of Varenicline (Chantix) and Bupropion (Zyban) on Smoking Lapse Behavior
ClinicalTrials.gov Identifier: NCT00580853 - Recruiting
Smoking Lapse Behavior
- Testing the Effectiveness of Low-Dose Naltrexone Combined with Bupropion to Stop Smoking With Less Weight Gain
ClinicalTrials.gov Identifier: NCT00129246 - Completed
Smoking; Nicotine Dependence
- Impact of Smoking Cessation on Sleep - 1
ClinicalTrials.gov Identifier: NCT00132821 - Recruiting
Tobacco Use Cessation; Tobacco Use Disorder
- Treatment of Adolescents with Comorbid Alcohol Use and Attention Deficit Hyperactivity Disorder (bupropion)
ClinicalTrials.gov Identifier: NCT00029614 - Completed
Alcoholism; Attention Deficit Hyperactivity Disorder
- Effect of Memantine Versus Bupropion on Smoking Relapse in Nicotine-Dependent Individuals - 3
ClinicalTrials.gov Identifier: NCT00136786 - Not yet recruiting
Tobacco Use Disorder
- Phase III Randomized Study of Nicotine Inhaler Versus Bupropion Versus Nicotine Inhaler Plus Bupropion for Smoking Cessation and Prevention of Relapse in Participants Who Currently Smoke
ClinicalTrials.gov Identifier: NCT00033592 - Completed
Small Cell Lung Cancer; prevention of lung cancer; Non-small cell lung cancer
- Bupropion Treatment for Youth Smoking Cessation
ClinicalTrials.gov Identifier: NCT00344695 - Completed
Nicotine Dependence
- The Effects of Acute Administration of Bupropion on Neural Substrates Underlying Hedonic Capacity
ClinicalTrials.gov Identifier: NCT00205946 - Completed
Major Depressive Disorder
- A Program to Quit Smoking With or Without Bupropion in Treating Patients With Stage I or II Non-Small Cell Lung Cancer Who Have Undergone Surgery
ClinicalTrials.gov Identifier: NCT00032084 - Completed
Non-small cell lung cancer; stage I non-small cell lung cancer; stage II non-small cell lung cancer
- Assessment of Bupropion on Cognitive Function and Behaviour in Healthy Volunteers
ClinicalTrials.gov Identifier: NCT00285155 - Completed
Healthy
- Safety and Efficacy of Different Combinations of Zonisamide-CR Plus Bupropion-SR to Treat Uncomplicated Obesity
ClinicalTrials.gov Identifier: NCT00339014 - Completed
Obesity
- Combinations of Pharmacologic Smoking Cessation Treatments
ClinicalTrials.gov Identifier: NCT00018187 - Completed
Smoking
- Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease
ClinicalTrials.gov Identifier: NCT00181818 - Completed
Smoking; Myocardial Infarction; Unstable Angina; Cardiovascular Disease
- Pharmacologic Relapse Prevention for Alcoholic Smokers
ClinicalTrials.gov Identifier: NCT00000457 - Completed
Alcoholism; Smoking
- Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation
ClinicalTrials.gov Identifier: NCT00484692 - Completed
Nicotine Dependence; Substance Abuse; Substance Dependence; Tobacco Dependence
- Bupropion SR for Treating Smokeless Tobacco Use
ClinicalTrials.gov Identifier: NCT00414180 - Completed
Smokeless Tobacco
- Use of Pharmacotherapy to Reduce Cue-Responsiveness in Smokers
ClinicalTrials.gov Identifier: NCT00133757 - Completed
Nicotine Dependence; Tobacco Dependence
- Cocaine Abuse and Attention Deficit Disorder - 3
ClinicalTrials.gov Identifier: NCT00000268 - Completed
Cocaine-Related Disorders
- Non-Nicotine Agents for Smoking Cessation
ClinicalTrials.gov Identifier: NCT00108537 - Completed
Tobacco Use Disorder
- Study Of Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT00135512 - Completed
Major Depressive Disorder
- A Trial of Wellbutrin for Crohn''s Disease
ClinicalTrials.gov Identifier: NCT00126373 - Completed
Crohn Disease
- Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
ClinicalTrials.gov Identifier: NCT00012558 - Completed
Mood Disorders; Affective Disorders, Psychotic; Bipolar Disorder; Cyclothymic Disorder
- Bupropion SR for Major Depression and Depression NOS in Children and Adolescents With Bipolar Disorder
ClinicalTrials.gov Identifier: NCT00181896 - Terminated
Depression; Bipolar Disorder
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