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Bosentan |
Tracleer |
Image:Bosentan.png Bosentan Systematic (IUPAC) name N-[6-(2-hydroxyethoxy)-5- (2-methoxyphenoxy) -2-pyrimidin-2-yl-pyrimidin-4-yl] -4-tert- butyl-benzenesulfonamide Identifiers CAS number 147536-97-8 ATC code C02KX01 PubChem 104865 DrugBank APRD00829 Chemical data Formula C27H29N5O6S Mol. weight 551.615 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? ...
Wikipedia - [full article]
Bosentan Clinical Trials
- Efficacy and Safety of Oral Bosentan in Patients with Idiopathic Pulmonary Fibrosis
ClinicalTrials.gov Identifier: NCT00071461 - Active, not recruiting
Idiopathic Pulmonary Fibrosis
- Bosentan in Treatment of Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00266162 - Active, not recruiting
Eisenmenger Syndrome
- Combination Treatment With Bosentan and Sildenafil to Patients With Eisenmengers Syndrome
ClinicalTrials.gov Identifier: NCT00303004 - Active, not recruiting
Eisenmenger Syndrome
- BUILD 3: Bosentan Use in Interstitial Lung Disease
ClinicalTrials.gov Identifier: NCT00391443 - Recruiting
Idiopathic Pulmonary Fibrosis
- Effects of Bosentan (Tracleer) in the Course of Pulmonary Artery Hypertension Induced by Hypoxia
ClinicalTrials.gov Identifier: NCT00260819 - Recruiting
Hypoxia-Induced Pulmonary Artery Hypertension
- Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH)
ClinicalTrials.gov Identifier: NCT00310830 - Active, not recruiting
Pulmonary Hypertension
- Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH)
ClinicalTrials.gov Identifier: NCT00313196 - Active, not recruiting
Pulmonary Hypertension
- Bosentan in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
ClinicalTrials.gov Identifier: NCT00319111 - Active, not recruiting
Pulmonary Hypertension
- Bosentan in Children With Pulmonary Arterial Hypertension Extension Study
ClinicalTrials.gov Identifier: NCT00319020 - Active, not recruiting
Pulmonary Hypertension
- Bosentan in Digital Ulcers
ClinicalTrials.gov Identifier: NCT00319696 - Active, not recruiting
Systemic Sclerosis; Digital Ulcers
- Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Scleroderma Patients
ClinicalTrials.gov Identifier: NCT00077584 - Completed
Systemic Sclerosis; Scleroderma
- Efficacy and Safety of Oral Bosentan in Pulmonary Arterial Hypertension Class II
ClinicalTrials.gov Identifier: NCT00091715 - Completed
Pulmonary Hypertension
- Combination Therapy of Bosentan and Aerosolized Iloprost in Idiopathic Pulmonary Arterial Hypertension (IPAH)
ClinicalTrials.gov Identifier: NCT00120380 - Active, not recruiting
Hypertension
- Placebo Controlled Trial of Bosentan in Scleroderma Patients
ClinicalTrials.gov Identifier: NCT00377455 - Recruiting
Systemic Scleroderma; Pulmonary Hypertension
- The Effect of Tracleer™ on Male Fertility
ClinicalTrials.gov Identifier: NCT00082186 - Active, not recruiting
Hypertension, Pulmonary
- Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00323297 - Recruiting
Pulmonary Hypertension
- Treatment of Early Systemic Sclerosis by Bosentan
ClinicalTrials.gov Identifier: NCT00226889 - Recruiting
Systemic Sclerosis (Scleroderma)
- Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)
ClinicalTrials.gov Identifier: NCT00303459 - Recruiting
Pulmonary Hypertension
- Efficacy and safety of oral bosentan in pulmonary fibrosis associated with scleroderma
ClinicalTrials.gov Identifier: NCT00070590 - Completed
Pulmonary Fibrosis; Scleroderma, Systemic
- Double Blind, Randomized Trial of Bosentan for Sarcoidosis Associated Pulmonary Hypertension
ClinicalTrials.gov Identifier: NCT00581607 - Not yet recruiting
Sarcoidosis; Pulmonary Arterial Hypertension
- Effect of Bosentan on Exercise Capacity at High Altitude
ClinicalTrials.gov Identifier: NCT00432978 - Completed
Altitude; Pulmonary Hypertension
- BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
ClinicalTrials.gov Identifier: NCT00367770 - Completed
Pulmonary Arterial Hypertension
- Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis
ClinicalTrials.gov Identifier: NCT00318175 - Completed
Systemic Scleroderma; Skin Fibrosis; Hand Functionality
- Bosentan in Children With Pulmonary Arterial Hypertension
ClinicalTrials.gov Identifier: NCT00319267 - Completed
Pulmonary Hypertension
- Open-Label Study With Bosentan in Interstitial Lung Disease
ClinicalTrials.gov Identifier: NCT00319033 - Completed
Interstitial Lung Disease; Scleroderma
- Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension
ClinicalTrials.gov Identifier: NCT00313222 - Completed
Chronic Thromboembolic Pulmonary Hypertension
- Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
ClinicalTrials.gov Identifier: NCT00317486 - Completed
Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
- Trial of Iloprost Inhaled Solution as Add-On Therapy with Bosentan in Subjects with Pulmonary Arterial Hypertension (PAH)
ClinicalTrials.gov Identifier: NCT00086463 - Completed
Pulmonary Arterial Hypertension; PAH; Pulmonary Hypertension
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