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Nesiritide |
Natrecor |
Nesiritide (Natrecor®) is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). A brain natriueretic peptide, nesiritide works to facilitate cardiovascular fluid homeostasis through counterregulation of the renin-angiotensin-aldoesterone system, stimulating cyclic guanosine monophosphate, leading to smooth muscle cell relaxation. In simpler terms, it promotes vasodilation, natriuresis, and d ...
Wikipedia - [full article]
Nesiritide Clinical Trials
- Nesiritide Infusion for the Treatment of Decompensated Heart Failure and Renal Dysfunction
ClinicalTrials.gov Identifier: NCT00119691 - Recruiting
Congestive Heart Failure; Renal Insufficiency
- The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure
ClinicalTrials.gov Identifier: NCT00110201 - Recruiting
Cardiovascular Disease; Acute Renal Failure; Death
- BNP (Nesiritide) Vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery.
ClinicalTrials.gov Identifier: NCT00252200 - Active, not recruiting
Acute Kidney Failure
- Renal Effects of Intrarenal Nesiritide
ClinicalTrials.gov Identifier: NCT00270829 - Recruiting
Heart Failure, Congestive
- Nesiritide Use Following Cardiac Surgery in Infants
ClinicalTrials.gov Identifier: NCT00281671 - Recruiting
Heart Defects, Congenital; Cardiopulmonary Bypass
- BELIEVE Study: Nesiritide and Post Myocardial Infarction Left Ventricular Modeling
ClinicalTrials.gov Identifier: NCT00252213 - Active, not recruiting
Myocardial Infarction
- Effects of Nesiritide in Pediatric Patients With Ventricular Failure
ClinicalTrials.gov Identifier: NCT00166010 - Recruiting
Ventricular Dysfunction; Heart Decompensation
- A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure
ClinicalTrials.gov Identifier: NCT00475852 - Recruiting
Heart Decompensation
- Study to Determine if Human BNP (Nesiritide) Will Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function
ClinicalTrials.gov Identifier: NCT00405639 - Recruiting
Congestive Heart Failure
- A Study of the Safety and Effectiveness of JNS004 (Nesiritide) in Patients With Acute Heart Failure
ClinicalTrials.gov Identifier: NCT00490724 - Recruiting
Heart Failure, Congestive
- Nesiritide Therapy to Preserve Function of the Left Ventricle After Myocardial Infarction
ClinicalTrials.gov Identifier: NCT00573144 - Recruiting
Acute Myocardial Infarction
- Study of Nesiritide in Diastolic Heart Failure.
ClinicalTrials.gov Identifier: NCT00309868 - Active, not recruiting
Diastolic Heart Failure
- Management of Patients with Congestive Heart Failure After Hospitalization
ClinicalTrials.gov Identifier: NCT00040612 - Active, not recruiting
Heart Failure, Congestive
- Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery
ClinicalTrials.gov Identifier: NCT00543309 - Recruiting
Fontan Operation; Cardiopulmonary Bypass; Heart Defects, Congenital; Milrinone; Natriuretic Peptide, Brain
- To Determine if Subcutaneous Injection of Human BNP, Natrecor (Nesiritide), a Hormone Produced by the Heart, Will Improve Kidney and Hormonal Function of People With Abnormal Function of Their Heart.
ClinicalTrials.gov Identifier: NCT00387621 - Recruiting
Congestive Heart Failure
- Follow-Up Serial Infusions of Natrecor(R) (nesiritide) for the Management of Patients with Heart Failure-FUSION II
ClinicalTrials.gov Identifier: NCT00091520 - Completed
Heart Failure, Congestive
- Nesiritide in Transplant-Eligible Management of Congestive Heart Failure-TMAC
ClinicalTrials.gov Identifier: NCT00338455 - Recruiting
Dialysis; Renal Failure; Renal Insufficiency.; Cardiac Transplantation; Congestive Heart Failure
- Nesiritide in Chronic Heart Failure
ClinicalTrials.gov Identifier: NCT00145873 - Terminated
Heart Failure
- Perioperative Treatment of Patients Undergoing Coronary Artery Bypass Surgery
ClinicalTrials.gov Identifier: NCT00090792 - Completed
- Impact of Nesiritide Infusion for Decompensated Heart Failure in the Emergency Department
ClinicalTrials.gov Identifier: NCT00559338 - Completed
Heart Failure, Congestive; Cardiomyopathy
- Nesiritide and Vo2 Max in Heart Failure Patients
ClinicalTrials.gov Identifier: NCT00240084 - Completed
Heart Failure
- A Safety Study Comparing Natrecor® (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure
ClinicalTrials.gov Identifier: NCT00270400 - Completed
Heart Failure, Congestive
- A Study of Two Doses of Intravenous NATRECOR® hBNP (Nesiritide) in Patients With Worsening Congestive Heart Failure Who Have Difficulty Breathing at Rest
ClinicalTrials.gov Identifier: NCT00288730 - Completed
Heart Decompensation; Heart Failure, Congestive
- FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR ® (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for Hos
ClinicalTrials.gov Identifier: NCT00270361 - Completed
Heart Failure, Congestive
- A Study to Develop Additional Safety and Clinical Experience With NATRECOR® hBNP (Nesiritide) in the Treatment of Patients With Worsening Congestive Heart Failure Who Require Inpatient Intravenous Therapy With Medications That Influence the Tone and Cali
ClinicalTrials.gov Identifier: NCT00271557 - Completed
Heart Failure, Congestive; Heart Decompensation
- A Study Comparing Blood Flow and Clinical and Safety Effects of the Addition of Natrecor® (Nesiritide), Placebo or Intravenous Nitroglycerin to Standard Care for the Treatment of Worsening Congestive Heart Failure.
ClinicalTrials.gov Identifier: NCT00270374 - Completed
Symptomatic Decompensated Congestive Heart Failure; Congestive Heart Failure in Acute Coronary Syndrome
- A Study of Short-Term Outcomes and Economic Impact For Patients With Worsening Congestive Heart Failure When Natrecor® (Nesiritide) is Added to Standard-Care Therapy, Compared to Administration of Placebo With Standard-Care Therapy.
ClinicalTrials.gov Identifier: NCT00270387 - Completed
Heart Failure, Congestive; Cardiomyopathies; Dyspnea, Paroxysma
- Use of Nesiritide in the Management of Acute Diastolic Heart Failure
ClinicalTrials.gov Identifier: NCT00083772 - Terminated
Heart Failure; Cardiovascular Disease; Acute Heart Failure; Diastolic Heart Failure; Congestive Heart Failure; Heart Disease
- Natrecor in Pulmonary Hypertension
ClinicalTrials.gov Identifier: NCT00075179 - Terminated
Pulmonary Hypertension; Cancer; Lung Disease; Cardiothoracic Surgery
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