Azathioprine is a chemotherapy drug, now rarely used for chemotherapy but more for immunosuppression in organ transplantation and autoimmune disease such as rheumatoid arthritis or Crohn's disease. It is a pro-drug, converted in the body to the active metabolite 6-mercaptopurine.


... AZATHIOPRINE (Imuran®) is an immunosuppressive agent. It can suppress or reduce the body''s natural immunity, making it less able to fight infections and preventing the rejection of ''foreign bodies''. Azathioprine reduces unwanted immune responses and helps to prevent rejection in patients who receive organ transplants. The response of the immune system may contribute to arthritis, and azathioprine helps to treat severe rheumatoid arthritis. Generic azathioprine tablets are available. ...
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Azathioprine Systematic (IUPAC) name 6-(3-methyl-5-nitro-imidazol ...
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Immunosuppressive Medicines: Azathioprine
... What is azathioprine? Azathioprine (Imuran) is an immunosuppressive medicine that prevents kidney rejection by interfering with the body''s normal immune response. One way the body fights a foreign or...
Source: Cleveland Clinic