Candesartan |
Atacand; candesartan cilexetil |
Candesartan Systematic (IUPAC) name 3-((2'-(2H-tetrazol-5-yl) biphenyl-4-yl)methyl)-2-ethoxy- 3H-benzo[d]imidazole-4-carboxylic acid Identifiers CAS number 139481-59-7 ATC code C09CA06 PubChem 2541 DrugBank APRD00420 Chemical data Formula C24H20N6O3 Mol. weight 440.45 Pharmacokinetic data Bioavailability 15% (candesartan cilexetil) Metabolism Candesartan cilexetil: intestinal wall; candesartan: hepatic (CYP2C9) Half life 5.1–10.5 hours Excretion Renal 3 ...
Wikipedia - [full article]
Candesartan Clinical Trials
- Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial of Cardiovascular Events in High-Risk Hypertensive Patients
ClinicalTrials.gov Identifier: NCT00125463 - Active, not recruiting
Hypertension; Cardiovascular Diseases
- Scandinavian Candesartan Acute Stroke Trial (SCAST)
ClinicalTrials.gov Identifier: NCT00120003 - Recruiting
Stroke
- Acute Candesartan Cilexetil Outcomes Stroke Trial (ACCOST)
ClinicalTrials.gov Identifier: NCT00108706 - Active, not recruiting
Cerebrovascular Accident; Acute Stroke
- Candesartan for Prevention of Cardiovascular Events After Cypher or Taxus Coronary Stenting (4C) Trial
ClinicalTrials.gov Identifier: NCT00139386 - Recruiting
Hypertension; Coronary Artery Disease; Coronary Angioplasty
- DIabetic Retinopathy Candesartan Trials
ClinicalTrials.gov Identifier: NCT00252694 - Active, not recruiting
Type 2 Diabetes
- DIabetic Retinopathy Candesartan Trials.
ClinicalTrials.gov Identifier: NCT00252720 - Active, not recruiting
Type 1 Diabetes
- Diabetic Retinopathy Candesartan Trials
ClinicalTrials.gov Identifier: NCT00252733 - Active, not recruiting
Type 1 Diabetes
- Candesartan Effectiveness Study in Pro-BNP
ClinicalTrials.gov Identifier: NCT00348686 - Active, not recruiting
Hypertension; Left Ventricular Hypertrophy
- Double-Blind Randomized Cross-Over Trial Comparing Metabolic Effects of Candesartan, Hydrochlorothiazide and Placebo
ClinicalTrials.gov Identifier: NCT00282178 - Active, not recruiting
Hypertension; Obesity
- Antihypertensive Efficacy and Safety of Candesartan/HCT 32/25 mg in Comparison With Individual Components and Placebo
ClinicalTrials.gov Identifier: NCT00434967 - Active, not recruiting
Hypertension
- Evaluating the Effect of Candesartan vs Placebo in Prevention of Trastuzumab-Associated Cardiotoxicity
ClinicalTrials.gov Identifier: NCT00459771 - Recruiting
Breast Cancer
- Efficacy Observational Study of Candesartan Cilexetil on Hypertensive Patients
ClinicalTrials.gov Identifier: NCT00573742 - Recruiting
Primary Hypertension
- Pharmacodynamic Influences of Candesartan, Atenolol, Hydrochlorothiazide and Drug Combinations in Hypertensive Patients.
ClinicalTrials.gov Identifier: NCT00232882 - Recruiting
Hypertension
- Antihypertensive Efficacy and Safety of Candesartan/HCT 32/12.5 and 32/25 mg in Comparison With Candesartan 32 mg
ClinicalTrials.gov Identifier: NCT00383929 - Completed
Hypertension
- Effectiveness of Candesartan and Telmisartan on Morning Hypertension in Japanese Obese Patients
ClinicalTrials.gov Identifier: NCT00288717 - Recruiting
Hypertension
- Effects of Antihypertensive Treatment in HIV Infected Patients: Candesartan Versus Lercanidipine
ClinicalTrials.gov Identifier: NCT00564057 - Recruiting
HIV Infections; Hypertension
- CHANCE - Candesartan in Hypertrophic Cardiomyopathy
ClinicalTrials.gov Identifier: NCT00430833 - Active, not recruiting
Hypertrophic Cardiomyopathy
- Danish Hypertension Prevention Project - DHYPP
ClinicalTrials.gov Identifier: NCT00150631 - Active, not recruiting
Prevent or delay development of hypertension
- Clinical Trial to Assess the Effects of Candesartan on the Carbohydrates Metabolism of Subjects With Dysglycemia and Abdominal Obesity."ARAMIA"
ClinicalTrials.gov Identifier: NCT00319202 - Recruiting
Glucose Intolerance; Obesity
- Candesartan in the Prevention of Relapsing Atrial Fibrillation
ClinicalTrials.gov Identifier: NCT00130975 - Completed
Atrial Fibrillation
- Investigation of Vascular Relaxing Effects of Candesartan and Pioglitazone.
ClinicalTrials.gov Identifier: NCT00154037 - Completed
Healthy subjects
- A Pharmacogenomic Study of Candesartan in Heart Failure
ClinicalTrials.gov Identifier: NCT00400582 - Recruiting
Heart Failure
- High Dose Candesartan Versus Quinapril for Restenosis Prophylaxis After Stent Angioplasty in Peripheral Occlusive Artery Disease.
ClinicalTrials.gov Identifier: NCT00154050 - Completed
occlusive arterial disease
- The Renin-Angiotensin System in Essential Hypertension
ClinicalTrials.gov Identifier: NCT00141583 - Recruiting
Hypertension
- A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients
ClinicalTrials.gov Identifier: NCT00538486 - Not yet recruiting
Hypertension; Obesity
- NIDDM and ACE2
ClinicalTrials.gov Identifier: NCT00192803 - Not yet recruiting
NIDDM patients
- Safety and Effects of Ramipril Combined With Candesartan
ClinicalTrials.gov Identifier: NCT00356395 - Completed
Hypertension
- Efficacy, Safety, & Pharmacokinetics of Candesartan Cilexetil in Hypertensive Paediatric Subjects 6 to < 17 Years of Age
ClinicalTrials.gov Identifier: NCT00244595 - Completed
Hypertension
- TROPHY - Candesartan Cilexetil Long-Term Hypertension Prevention Trial
ClinicalTrials.gov Identifier: NCT00227318 - Completed
Hypertension
- High Doses of Candesartan Cilexetil on the Reduction of Proteinuria
ClinicalTrials.gov Identifier: NCT00242346 - Completed
Proteinuria
- Angiotensin-II Blockade in Mitral Regurgitation
ClinicalTrials.gov Identifier: NCT00014846 - Completed
Heart Diseases; Mitral Valve Insufficiency
Resources
- Atacand (Drug Digest)
- Atacand Consumer Information (U.S. Food and Drug Administration)

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