Not Signed In -
Leflunomide |
Arava |
Leflunomide Systematic (IUPAC) name 5-methyl-N-[4-(trifluoromethyl) phenyl]-isoxazole-4-carboxamide Identifiers CAS number 75706-12-6 ATC code L04AA13 PubChem 3899 DrugBank APRD00205 Chemical data Formula C12H9F3N2O2 Mol. weight 270.207 g/mol Pharmacokinetic data Bioavailability 80% Protein binding >99.3% Metabolism ? Half life 2 weeks Excretion ? Therapeutic considerations Pregnancy cat. X (contraindicated) Legal status Rx only ...
Wikipedia - [full article]
Leflunomide Clinical Trials
- Effect of Leflunomide on T cell Proliferation in HIV-Infected Patients
ClinicalTrials.gov Identifier: NCT00101374 - Active, not recruiting
HIV Infections
- Leflunomide in Treating Patients With Anaplastic Astrocytoma in First Relapse
ClinicalTrials.gov Identifier: NCT00003775 - Active, not recruiting
adult anaplastic astrocytoma; Quality of Life; recurrent adult brain tumor; Mixed Gliomas
- Triple III Comparison of Leflunomide Alone Versus Two DMARD Combinations in the Treatment of Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00579878 - Active, not recruiting
Rheumatoid Arthritis
- Lupus Immunosuppressive/Immunomodulatory Therapy or Stem Cell Transplant (LIST)
ClinicalTrials.gov Identifier: NCT00230035 - Recruiting
Systemic Lupus Erythematosus
- Mitoxantrone and Prednisone With or Without Leflunomide in Treating Patients With Stage IV Prostate Cancer
ClinicalTrials.gov Identifier: NCT00004071 - Completed
stage IV prostate cancer; recurrent prostate cancer; Quality of Life
- Induction Treatment of Proliferative Lupus Nephritis With Leflunomide Combined With Prednisone
ClinicalTrials.gov Identifier: NCT00268567 - Completed
Nephritis, Lupus
- Leflunomide to Treat Uveitis
ClinicalTrials.gov Identifier: NCT00001863 - Completed
Uveitis
- Leflunomide + Methotrexate in Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00563849 - Completed
Rheumatoid Arthritis
- Leflunomide in Rheumatoid Arthritis
ClinicalTrials.gov Identifier: NCT00280644 - Completed
Arthritis, Rheumatoid
- SU-101 Compared With Procarbazine in Treating Patients With Glioblastoma Multiforme
ClinicalTrials.gov Identifier: NCT00003293 - Completed
adult glioblastoma multiforme; Quality of Life; recurrent adult brain tumor
Resources
- Arava (Drug Digest)
- Drugnamexxx Consumer Information (U.S. Food and Drug Administration)
email this page
print this page
bookmark this page
feedback on this page
