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Darbepoetin alfa |
Aranesp |
Image:Darbepoetin alfa.png Darbepoetin alfa Systematic (IUPAC) name ? Identifiers CAS number 11096-26-7 ATC code B03XA02 PubChem ? DrugBank BTD00032 Chemical data Formula C815H1317N233O241S5 Mol. weight 18396.1 g/mol Pharmacokinetic data Bioavailability ? Metabolism ? Half life ? Excretion ? Therapeutic considerations Pregnancy cat. ? Legal status Routes ? Darbepoetin alfa (rINN) (IPA: [dabəˈpɔɪtn] ...
Wikipedia - [full article]
Darbepoetin alfa Clinical Trials
- Darbepoetin Alfa Compared With Epoetin alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer
ClinicalTrials.gov Identifier: NCT00046982 - Active, not recruiting
Fatigue; Anemia; unspecified adult solid tumor, protocol specific
- Darbepoetin alfa Compared With Epoetin alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer
ClinicalTrials.gov Identifier: NCT00070382 - Active, not recruiting
adult solid tumor; Anemia; Leukemia; Lymphoma; plasma cell neoplasm
- D.O.S.E. Registry
ClinicalTrials.gov Identifier: NCT00212862 - Active, not recruiting
Cancer; Anemia; Epoetin Alfa; Darbepoetin Alfa
- A Study of Subjects with Previously Untreated Extensive-Stage Small-Cell Lung Cancer (SCLC) Treated with Platinum Plus Etoposide Chemotherapy with Or Without Darbepoetin Alfa
ClinicalTrials.gov Identifier: NCT00119613 - Active, not recruiting
Small Cell Lung Cancer
- Darbepoetin alfa in Treating Anemia in Patients With Cancer Who Are Receiving Chemotherapy
ClinicalTrials.gov Identifier: NCT00039247 - Active, not recruiting
Anemia; unspecified adult solid tumor, protocol specific
- Darbepoetin alfa in Treating Anemic Patients With Myelodysplastic Syndromes
ClinicalTrials.gov Identifier: NCT00093691 - Recruiting
Anemia; Fatigue; Myelodysplastic Syndromes
- Hematologic Response of Epoetin Alfa (PROCRIT) Versus Darbepoetin Alfa (ARANESP) in Chemotherapy Induced Anemia
ClinicalTrials.gov Identifier: NCT00315484 - Active, not recruiting
Chemotherapy; Anemia
- Cost-Effectiveness Study of Epoetin Alfa and Darbepoetin Alfa in Adult Patients With Cancer Who Have Anemia
ClinicalTrials.gov Identifier: NCT00264108 - Recruiting
Neoplasms; Anemia
- A Study of Darbepoetin Alfa for the Treatment of Anemia in Subjects with Non-Myeloid Malignancy Receiving Multicycle Chemotherapy
ClinicalTrials.gov Identifier: NCT00118638 - Completed
Anemia
- Pegfilgrastim and Darbepoetin Alfa in Support of Adjuvant Chemotherapy for Breast Cancer
ClinicalTrials.gov Identifier: NCT00146562 - Active, not recruiting
Breast Cancer; stage I breast cancer; Stage II breast cancer
- Darbepoetin Alfa Administered Once Every 4 Weeks in the Treatment of Subjects with Anemia of Cancer
ClinicalTrials.gov Identifier: NCT00095277 - Completed
Anemia
- A Study of Darbepoetin Alfa for the Treatment of Anemia in Subjects with a Non-Myeloid Malignancy
ClinicalTrials.gov Identifier: NCT00117624 - Completed
Anemia
- A Study of Darbepoetin Alfa in Anemic Subjects Not Receiving Chemotherapy who Have Completed the 20010103 Study
ClinicalTrials.gov Identifier: NCT00115167 - Completed
Anemia
- Epoetin Alfa or Darbepoetin Alfa in Treating Patients With Anemia Caused by Chemotherapy
ClinicalTrials.gov Identifier: NCT00416624 - Recruiting
Anemia; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Unspecified Adult Solid Tumor, Protocol Specific
- Darbepoetin Alfa Treatment of Anemia in Hemodialysis Subjects
ClinicalTrials.gov Identifier: NCT00119587 - Completed
Anemia
- Darbepoetin alfa in Treating Anemia in Patients With Non-Myeloid Cancer Who Are Not Receiving Chemotherapy
ClinicalTrials.gov Identifier: NCT00098696 - Recruiting
adult solid tumor; Anemia; Leukemia; Lymphoma; plasma cell neoplasm
- A Study of Darbepoetin Alfa in Anemic Subjects with Low Risk Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00095264 - Completed
Myelodysplastic Syndromes
- OPUS Efficacy Study: Darbepoetin Alfa for the Treatment of Anemia in Patients with Chronic Kidney Disease
ClinicalTrials.gov Identifier: NCT00121602 - Completed
Anemia; Kidney Disease
- Darbepoetin Alfa With or Without IV Iron
ClinicalTrials.gov Identifier: NCT00401544 - Not yet recruiting
Anemia; Non-Myeloid Malignancies
- Study of Darbepoetin Alfa for the Treatment of Anemia of Cancer
ClinicalTrials.gov Identifier: NCT00091858 - Completed
Anemia; Cancer
- A Study of Darbepoetin Alfa in Patients With Myelodysplastic Syndrome (MDS)
ClinicalTrials.gov Identifier: NCT00230321 - Active, not recruiting
Myelodysplastic Syndrome
- Fludarabine and Darbepoetin Alfa in Treating Older Patients With Chronic Lymphocytic Leukemia
ClinicalTrials.gov Identifier: NCT00281892 - Recruiting
Anemia; Leukemia
- Study Evaluating Darbepoetin Alfa in Subjects with Chronic Kidney Disease (CKD) Receiving Dialysis
ClinicalTrials.gov Identifier: NCT00096915 - Completed
Kidney Diseases; Chronic Disease
- Effect of Darbepoetin Alfa (Aranesp®) on Anemia in Patients With Advanced Hormone Independent Prostate Cancer
ClinicalTrials.gov Identifier: NCT00381836 - Recruiting
Prostatic Neoplasms; Anemia
- Extension From Weekly to Once Every Other Week Darbepoetin Alfa Administration in Subjects With Chronic Kidney Disease Receiving Dialysis
ClinicalTrials.gov Identifier: NCT00436995 - Active, not recruiting
Chronic Kidney Disease
- Impact of Darbepoetin Alfa on Exercise Tolerance and Left Ventricular Structure in Subjects with Symptomatic Congestive Heart Failure (CHF) and Anemia
ClinicalTrials.gov Identifier: NCT00117234 - Completed
Congestive Heart Failure; Anemia
- An Exploratory Sub-Study for the RED-HF™ (Reduction of Events With Darbepoetin Alfa in Heart Failure) Trial
ClinicalTrials.gov Identifier: NCT00534456 - Active, not recruiting
Anemia; Cardiovascular Disease; Congestive Heart Failure; Heart Failure; Ventricular Dysfunction
- Subcutaneous (SC) Darbepoetin Alfa in Subjects with Symptomatic Congestive Heart Failure (CHF) & Anemia
ClinicalTrials.gov Identifier: NCT00086086 - Completed
Heart Failure, Congestive; Anemia
- Darbepoetin Alfa in Patients With "Poor Prognosis" Germ Cell Tumor Treated With High-Dose Chemotherapy (HD-VIP)
ClinicalTrials.gov Identifier: NCT00204633 - Recruiting
Dysgerminoma
- ACCELERATE: Doxorubicin and Cyclophosphamide Followed by Paclitaxel With Pegfilgrastim and Darbepoetin Alfa Support for the Treatment of Women With Breast Cancer
ClinicalTrials.gov Identifier: NCT00261313 - Recruiting
Breast Cancer
- Combination Chemotherapy With or Without Darbepoetin Alfa in Treating Women With Stage III Breast Cancer
ClinicalTrials.gov Identifier: NCT00309920 - Recruiting
Breast Cancer
- Azacitidine, Darbepoetin Alfa, and G-CSF in Treating Patients With Myelodysplastic Syndromes
ClinicalTrials.gov Identifier: NCT00398047 - Recruiting
Leukemia; Myelodysplastic Syndromes
- Study to Assess Darbepoetin Alfa in Subjects with Chronic Kidney Disease
ClinicalTrials.gov Identifier: NCT00093977 - Completed
Kidney Disease; Chronic Disease
- Study for the Treatment of Anemia in Patients with Non-Myeloid Malignancies Receiving Multicycle Chemotherapy.
ClinicalTrials.gov Identifier: NCT00148421 - Completed
Anemia
- A Study of Repeat-Dose Subcutaneous Darbepoetin Alfa in Subjects with Congestive Heart Failure and Anemia, and a Single Dose in Healthy Age- and Sex-Matched Control Subjects
ClinicalTrials.gov Identifier: NCT00117247 - Completed
Anemia; Congestive Heart Failure
- Safety of Darbepoetin Alfa Treatment in Patients With Severe Traumatic Brain Injury
ClinicalTrials.gov Identifier: NCT00375869 - Recruiting
Traumatic Brain Injury
- The Effect of Darbepoetin Upon Rehabilitation for Colorectal Cancer Surgery
ClinicalTrials.gov Identifier: NCT00122720 - Completed
Colorectal Cancer
- A Web-Based Study of Quality of Life Benefits Associated Aranesp in Anemic Patients with Cancer.
ClinicalTrials.gov Identifier: NCT00153868 - Recruiting
Anemia; Cancer
- RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial
ClinicalTrials.gov Identifier: NCT00358215 - Recruiting
Heart Failure; Anemia; Cardiovascular Disease; Ventricular Dysfunction; Congestive Heart Failure
- Phase 2 Study of Darbepoetin Alfa Extended Dosing
ClinicalTrials.gov Identifier: NCT00527215 - Completed
Pre-Dialysis
- Trial to Reduce Cardiovascular Events with Aranesp® Therapy (TREAT)
ClinicalTrials.gov Identifier: NCT00093015 - Recruiting
Kidney Diseases; Nephritis; Diabetes Mellitus
- Darbepoetin Alfa (Aranesp) Following Allogeneic Stem Cell Transplantation
ClinicalTrials.gov Identifier: NCT00355407 - Completed
Hematologic Malignancies
- Efficacy of Albumin Interferon Alfa-2b With Ribavirin Compared With Peg-IFN Alfa-2a With Ribavirin in IFN Naive Patients
ClinicalTrials.gov Identifier: NCT00402428 - Active, not recruiting
Chronic Hepatitis C
- Efficacy of Albumin Interferon Alfa-2b With Ribavirin Compared to Peg-IFN Alfa-2a With Ribavirin in IFN Naive Patients Geno2/3
ClinicalTrials.gov Identifier: NCT00411385 - Active, not recruiting
Chronic Hepatitis C
- A Dose Finding Study of KRN321(Darbepoetin Alfa) for the Treatment of Anemia in Subjects With Solid Tumor
ClinicalTrials.gov Identifier: NCT00359840 - Completed
Anemia
- Study to Assess Darbepoetin Alfa Dosing for the Correction of Anemia in Pediatric Subjects With Chronic Kidney Disease
ClinicalTrials.gov Identifier: NCT00436748 - Not yet recruiting
Anemia; Chronic Kidney Disease; Kidney Disease
- R-CHOP-14 Versus R-CHOP-21 and Darbepoetin Alpha in Patients Aged 66-80 Years with Diffuse Large B-Cell Lymphoma
ClinicalTrials.gov Identifier: NCT00144755 - Recruiting
Diffuse Large Cell Lymphoma
- Study of the Efficacy of Darbepoetin Alfa in the Treatment of Renal Anemia
ClinicalTrials.gov Identifier: NCT00563446 - Completed
Anemia; Kidney Failure, Chronic; Peritoneal Dialysis, Continuous Ambulatory
- Docetaxel and Cisplatin With or Without Dimesna in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00077311 - Active, not recruiting
Anemia; Drug Toxicity; Neutropenia; Non-small cell lung cancer
- Study to Develop a Screening Tool for Functional Capacity in Anemic Subjects With Nonmyeloid Malignancies Receiving Chemotherapy and Darbepoetin Alfa
ClinicalTrials.gov Identifier: NCT00540696 - Completed
Anemia; Non-Myeloid Malignancies
- Treatment of Anemia in Subjects with Non-Myeloid Malignancy Receiving Multicycle Chemotherapy
ClinicalTrials.gov Identifier: NCT00110955 - Completed
Anemia
- Combination Chemotherapy Plus Interferon alfa or Rituximab in Treating Patients With Stage III or Stage IV Lymphoma
ClinicalTrials.gov Identifier: NCT00004039 - Active, not recruiting
Lymphoma
- Reduction of Immunosuppression Plus Interferon alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant
ClinicalTrials.gov Identifier: NCT00002657 - Active, not recruiting
Lymphoma; Multiple Myeloma
- Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer
ClinicalTrials.gov Identifier: NCT00002504 - Active, not recruiting
Lymphoma; Leukemia
- COMFORT Study: A Crossover Study of NeoRecormon (Epoetin Beta) and Darbepoetin Alfa in Patients With Renal Anemia.
ClinicalTrials.gov Identifier: NCT00377481 - Completed
Anemia
- Interferon Alfa in Treating Children With HIV-Related Cancer
ClinicalTrials.gov Identifier: NCT00002621 - Active, not recruiting
Leukemia; Lymphoma
- Treatment for Anemic Subjects with Non-Myeloid Malignancies Receiving Chemotherapy
ClinicalTrials.gov Identifier: NCT00120705 - Completed
Neoplasms; Anemia
- A Safety and Efficacy Study of Prophylactically Administered Pegylated Interferon alfa-2a (Pegasys) plus Ribavirin vs. No Prophylaxis Following Liver Transplantation for Hepatitis C
ClinicalTrials.gov Identifier: NCT00087633 - Active, not recruiting
Hepatitis C
- Safety and Tolerability of Pegylated Interferon (PEG-IFN) Alfa-2a in HIV Infected People
ClinicalTrials.gov Identifier: NCT00078442 - Active, not recruiting
HIV Infections
- Treatment for Subjects with Chronic Kidney Disease (CKD) Not Receiving Dialysis
ClinicalTrials.gov Identifier: NCT00111098 - Completed
Kidney Diseases
- A Study to Evaluate the Combination of Pegylated Interferon Alfa Plus Valopicitabine in Patients with Hepatitis C
ClinicalTrials.gov Identifier: NCT00118768 - Active, not recruiting
Chronic Hepatitis C
- Zidovudine Levels in HIV Infected Patients Being Treated for HCV
ClinicalTrials.gov Identifier: NCT00059358 - Active, not recruiting
HIV Infections; Hepatitis C
- Vaccine Therapy Compared With Interferon alfa in Treating Patients With Stage III Melanoma
ClinicalTrials.gov Identifier: NCT00003715 - Active, not recruiting
stage III melanoma
- Interleukin-12 Followed by Interferon alfa in Treating Patients With Advanced Cancer
ClinicalTrials.gov Identifier: NCT00003451 - Active, not recruiting
Cancer
- Cisplatin, Interferon alfa, Surgery, and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
ClinicalTrials.gov Identifier: NCT00003263 - Active, not recruiting
localized malignant mesothelioma
- SU011248 versus Interferon-alfa as First-Line Systemic Therapy for Patients with Metastatic Renal Cell Carcinoma
ClinicalTrials.gov Identifier: NCT00083889 - Active, not recruiting
Renal Cell Carcinoma
- Interferon-alfa With or Without Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
ClinicalTrials.gov Identifier: NCT00002868 - Active, not recruiting
chronic phase chronic myelogenous leukemia
- AIM 3: Anemia and Iron Management with Every 3 Week Dosing
ClinicalTrials.gov Identifier: NCT00135317 - Completed
Cancer; Non-myeloid malignancy
- Darbepoetin Administration to Preterm Infants
ClinicalTrials.gov Identifier: NCT00334737 - Recruiting
Infant, Newborn
- Pegylated Interferon Alfa-2a Maintenance Therapy and Liver Disease Progression in People Infected With Both HIV and Hepatitis C Virus (HCV)
ClinicalTrials.gov Identifier: NCT00078403 - Active, not recruiting
HIV Infections; Hepatitis C; Liver Disease
- Thymosin Plus PEG-Interferon in Non-Cirrhotic Hepatitis C Patients Who Did Not Respond to Interferon or Interferon Plus Ribavirin
ClinicalTrials.gov Identifier: NCT00040027 - Active, not recruiting
Hepatitis C; Hepatitis C, Chronic
- Radiation Therapy With or Without Epoetin alfa in Treating Patients With Head and Neck Cancer
ClinicalTrials.gov Identifier: NCT00017277 - Active, not recruiting
Oral Cancer; Throat Cancer
- Interferon alfa in Treating Patients With Recurrent Unresectable Meningiomas and Malignant Meningiomas
ClinicalTrials.gov Identifier: NCT00002965 - Active, not recruiting
recurrent adult brain tumor
- Interferon alfa With or Without Vaccine Therapy in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00002767 - Active, not recruiting
Stage IV Melanoma; Recurrent Melanoma; Quality of Life
- A Study of Four Dosing Regimens of PROCRIT® (Epoetin Alfa) in Patients with Chronic Kidney Disease
ClinicalTrials.gov Identifier: NCT00212875 - Active, not recruiting
Kidney Diseases; Injections, Subcutaneous; Anemia
- Vaccine Therapy Plus Interleukin-2 With or Without Interferon alfa-2b in Treating Patients With Stage III Melanoma
ClinicalTrials.gov Identifier: NCT00004104 - Active, not recruiting
stage III melanoma
- Interferon alfa Following Surgery in Treating Patients With Stage III Melanoma
ClinicalTrials.gov Identifier: NCT00006249 - Active, not recruiting
stage III melanoma
- Interferon alfa-2b With or Without Radiation Therapy in Treating Patients With Melanoma That Has Metastasized to Lymph Nodes in the Neck, Under the Arm, or in the Groin
ClinicalTrials.gov Identifier: NCT00003444 - Active, not recruiting
Stage IV Melanoma; stage III melanoma; Recurrent Melanoma
- Epoetin Alfa in Treating Fatigue in Patients With Advanced Solid Tumors Who Are Not Receiving Chemotherapy
ClinicalTrials.gov Identifier: NCT00052221 - Active, not recruiting
unspecified adult solid tumor, protocol specific; Fatigue
- Combination Chemotherapy With or Without Interleukin-2 and Interferon alfa in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00003027 - Active, not recruiting
Stage IV Melanoma
- Anemia in Patients with a Non-Myeloid Malignancy
ClinicalTrials.gov Identifier: NCT00038064 - Completed
Anemia; Neoplasms
- Treatment for Patients Suffering from Anemia Due to Chemotherapy
ClinicalTrials.gov Identifier: NCT00120692 - Completed
Breast Cancer; Anemia
- Dexamethasone Plus Interferon alfa in Treating Patients With Primary Systemic Amyloidosis
ClinicalTrials.gov Identifier: NCT00002849 - Active, not recruiting
primary systemic amyloidosis
- Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer
ClinicalTrials.gov Identifier: NCT00019474 - Active, not recruiting
Pancreatic Cancer; Gastric Cancer; adult primary liver cancer
- High-Dose or Low-Dose Interferon alfa Compared With No Further Therapy Following Surgery in Treating Patients With Stage III Melanoma
ClinicalTrials.gov Identifier: NCT00002763 - Active, not recruiting
stage III melanoma; Recurrent Melanoma
- Epoetin alfa With or Without Filgrastim Compared With Blood Transfusions in Treating Patients With Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00003138 - Active, not recruiting
Anemia; Myelodysplastic Syndromes; Quality of Life
- Evaluation of Iron Supplementation During Darbepoetin Alfa Treatment in Prophylaxis of Severe Anaemia Chemo-Induced
ClinicalTrials.gov Identifier: NCT00210002 - Terminated
Neoplasms; Anemia
- A Study to Investigate the Neuroprotective Effect of PROCRIT® (Epoetin Alfa) Versus Placebo in Ovarian Cancer Patients Who Develop Chemotherapy-Induced Peripheral Neuropathy
ClinicalTrials.gov Identifier: NCT00267007 - Active, not recruiting
Peripheral Neuropathy, Chemotherapy-Induced; Ovarian Cancer
- Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus with Standard Treatment
ClinicalTrials.gov Identifier: NCT00006164 - Active, not recruiting
Chronic Hepatitis C; Cirrhosis, Liver; Fibrosis, Liver; Hepatic Cirrhosis
- Interferon alfa With or Without Combination Chemotherapy Plus Interleukin-2 in Treating Patients With Melanoma
ClinicalTrials.gov Identifier: NCT00002882 - Active, not recruiting
stage III melanoma
- Combination Chemotherapy and Interferon alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma
ClinicalTrials.gov Identifier: NCT00002599 - Active, not recruiting
stage I multiple myeloma; stage II multiple myeloma; stage III multiple myeloma
- Exercise Plus Epoetin Alfa in Treating Cancer Patients Who Have Anemia-Related Fatigue
ClinicalTrials.gov Identifier: NCT00004914 - Active, not recruiting
Anemia; unspecified adult solid tumor, protocol specific; Fatigue
- Interferon alfa Plus Radiation Therapy in Treating Patients With Stage III or Recurrent Melanoma That Has Been Removed by Surgery
ClinicalTrials.gov Identifier: NCT00005615 - Active, not recruiting
stage III melanoma; Recurrent Melanoma
- Combination Chemotherapy, Interferon alfa, and Interleukin-2 in Treating Patients With Metastatic Melanoma
ClinicalTrials.gov Identifier: NCT00002669 - Active, not recruiting
Stage IV Melanoma; Recurrent Melanoma
- Interferon alfa With or Without Interleukin-2 and Fluorouracil in Treating Patients With Advanced Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00053820 - Active, not recruiting
Stage IV Renal Cell Cancer
- Fractionated Dosing Study: Study to Evaluate Darbepoetin Alfa for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies
ClinicalTrials.gov Identifier: NCT00239239 - Completed
Non-Myeloid Malignancies; Anemia; Cancer
- Epoetin alfa in Treating Anemia in Patients With Solid Tumors
ClinicalTrials.gov Identifier: NCT00058331 - Active, not recruiting
adult solid tumor; Anemia; Leukemia; Lymphoma; plasma cell neoplasm
- Epoetin alfa in Treating Anemia in Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma and Anemia Caused By Chemotherapy
ClinicalTrials.gov Identifier: NCT00003341 - Active, not recruiting
Lymphoma; Leukemia; Multiple Myeloma
- PEG-Interferon alfa-2b in Treating Patients With Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00045279 - Active, not recruiting
Stage IV Renal Cell Cancer
- Epoetin alfa in Treating Cancer-Related Anemia in Patients With Non-Myeloid Cancer Who Are Not Currently Receiving Chemotherapy or Radiation Therapy
ClinicalTrials.gov Identifier: NCT00090935 - Active, not recruiting
adult solid tumor; Anemia; Leukemia; Lymphoma; plasma cell neoplasm
Resources
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