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Amantadine |
Symadine; Symmetrel |
Amantadine Systematic (IUPAC) name adamantan-1-amine Identifiers CAS number 768-94-5 ATC code N04BB01 PubChem 9036 DrugBank APRD00787 Chemical data Formula C10H17N Mol. weight 151.249 g/mol Pharmacokinetic data Bioavailability well absorbed Protein binding approx 67% Metabolism negligible Half life 10-14 hours, in renal impairment upto 7-10 days Excretion renal Therapeutic considerations Pregnancy cat. ? Legal status Routes oral Aman ...
Wikipedia - [full article]
Amantadine Clinical Trials
- Peginterferon Alfa-2a, Ribavirin, Amantadine/Placebo in HCV-Genotype-1-Infection (PRAMA)
ClinicalTrials.gov Identifier: NCT00127777 - Active, not recruiting
Hepatitis C, Chronic
- Amantadine for the Treatment of Behavioral Disturbance in Frontotemporal Dementia (FTD)
ClinicalTrials.gov Identifier: NCT00127114 - Recruiting
Dementia
- Propranolol and Amantadine for Cocaine Dependence
ClinicalTrials.gov Identifier: NCT00128349 - Active, not recruiting
Cocaine Dependence
- Study on Chronic Hepatitis C Treatment with Interferon Alpha, Ribavirin and Amantadine in Naive Patients
ClinicalTrials.gov Identifier: NCT00146016 - Completed
Chronic Hepatitis C
- Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4
ClinicalTrials.gov Identifier: NCT00000301 - Completed
Cocaine-Related Disorders
- Effect of Propranolol and Amantadine for Treating Cocaine Dependence - 2
ClinicalTrials.gov Identifier: NCT00158132 - Completed
Cocaine-Related Disorders
- Study of Amantadine for Weight Stabilization During Olanzapine Treatment
ClinicalTrials.gov Identifier: NCT00287352 - Recruiting
Psychotic Disorder; Schizophreniform Disorder; Schizophrenia; Schizoaffective Disorder
- Safety and Pharmacokinetic Effects of Oseltamivir Alone or in Combination With Amantadine
ClinicalTrials.gov Identifier: NCT00416962 - Completed
Healthy
- Peginterferon Alfa-2a Plus Ribavirin Plus Amantadine for the Treatment of Hepatitis C Infected Patients
ClinicalTrials.gov Identifier: NCT00221624 - Completed
HCV Infection; Hepatitis C, Chronic
- Study of the Pharmacokinetic Action of Amantadine and Ribavirin in Chronic Hepatitis C. CINAM
ClinicalTrials.gov Identifier: NCT00199719 - Completed
Chronic Hepatitis C
- Triple Therapy with Peg-Interferon Alfa-2b/Ribavirin Plus Amantadine Compared to Standard Peg-Interferon Alfa-2b/Ribavirin for Previous HCV Non Responders
ClinicalTrials.gov Identifier: NCT00122629 - Terminated
Hepatitis C, Chronic
- Treatment of Huntington's Chorea with Amantadine
ClinicalTrials.gov Identifier: NCT00001930 - Completed
Chorea; Huntington's Disease
- Pharmacotherapy for Schizophrenic Drug Users - 6
ClinicalTrials.gov Identifier: NCT00000281 - Completed
Cocaine-Related Disorders; Substance-Related Disorders
- Modeling Impaired Judgement in Cocaine Abusers - 6
ClinicalTrials.gov Identifier: NCT00015236 - Completed
Cocaine-Related Disorders; Substance-Related Disorders
- Prepulse Inhibition of Startle in Cocaine Dependence - 7
ClinicalTrials.gov Identifier: NCT00015249 - Completed
Cocaine-Related Disorders; Substance-Related Disorders
Resources
- Amantadine (Drug Digest)
- Symadine (Drug Digest)
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