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Tretinoin |
Altinac; Avita; Renova; Retin A Micro Gel; Retin-A |
Tretinoin Systematic (IUPAC) name 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl) -nona-2,4,6,8-tetraenoic acid Identifiers CAS number 302-79-4 ATC code D10AD01 D10AD04, D10BA01, L01XX14, L01XX22 PubChem 5538 DrugBank APRD00362 Chemical data Formula C20H28O2 Mol. weight 300.435 g/mol Pharmacokinetic data Bioavailability ? Protein binding > 95% Metabolism ? Half life 0.5-2 hours Excretion ? Therapeutic considerations Pregnancy ca ...
Wikipedia - [full article]
Tretinoin Clinical Trials
- Tretinoin in Preventing Cancer of the Cervix in Patients With Cervical Neoplasia
ClinicalTrials.gov Identifier: NCT00003598 - Active, not recruiting
Cervical Cancer
- Arsenic Trioxide With or Without Tretinoin in Treating Patients With Hematologic Cancer That Has Not Responded to Previous Therapy
ClinicalTrials.gov Identifier: NCT00006220 - Active, not recruiting
Leukemia; Lymphoma
- Determine the efficacy of topical tretinoin cream for the prevention of nonmelanoma skin cancer
ClinicalTrials.gov Identifier: NCT00007631 - Active, not recruiting
nonmelanoma skin cancer
- Study to Compare the Acne Relapse Rate of Oral Minocycline to Oral Minocycline in Combination With Topical Tretinoin, Followed by Topical Tretinoin Alone
ClinicalTrials.gov Identifier: NCT00240513 - Recruiting
Acne Vulgaris
- Tretinoin, Cytarabine, and Daunorubicin With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00003934 - Active, not recruiting
untreated adult acute myeloid leukemia; untreated childhood acute myeloid leukemia and other myeloid malignancies; ...
- Liposomal Tretinoin in Treating Patients With Recurrent or Refractory Hodgkin's Disease
ClinicalTrials.gov Identifier: NCT00005969 - Active, not recruiting
recurrent childhood Hodgkin's disease; recurrent adult Hodgkin's disease
- Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus Syndrome
ClinicalTrials.gov Identifier: NCT00003601 - Active, not recruiting
stage I melanoma; stage II melanoma; prevention of skin cancer
- Tretinoin Plus Interferon alfa in Treating Patients With Metastatic Kidney Cancer
ClinicalTrials.gov Identifier: NCT00003656 - Active, not recruiting
Stage IV Renal Cell Cancer; recurrent renal cell cancer
- Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00005863 - Active, not recruiting
Acute Myeloid Leukemia; adult acute monoblastic and acute monocytic leukemia; atypical chronic myeloid leukemia; childhood acute monocytic leukemia; ...
- Tretinoin and Interleukin-2 in Treating Patients With Stage IV Kidney Cancer
ClinicalTrials.gov Identifier: NCT00100906 - Active, not recruiting
Stage IV Renal Cell Cancer; recurrent renal cell cancer; renal clear cell carcinoma
- Tretinoin and Arsenic Trioxide With or Without Idarubicin in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00528450 - Recruiting
Leukemia
- Combination Chemotherapy With or Without Gemtuzumab Followed By Tretinoin, Mercaptopurine, and Methotexate or Observation in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00492856 - Recruiting
Leukemia
- Decitabine and Tretinoin in Treating Patients With Myelodysplastic Syndromes
ClinicalTrials.gov Identifier: NCT00382200 - Recruiting
Myelodysplastic Syndromes
- Bexarotene, Tretinoin, and Combination Chemotherapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00514293 - Recruiting
Lung Cancer
- Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome
ClinicalTrials.gov Identifier: NCT00005823 - Active, not recruiting
Acute Myeloid Leukemia; adult acute monoblastic and acute monocytic leukemia; atypical chronic myeloid leukemia; Chronic Myelomonocytic Leukemia; ...
- Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia
ClinicalTrials.gov Identifier: NCT00002658 - Active, not recruiting
Myeloid Leukemia; Neutropenia
- Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00002701 - Active, not recruiting
untreated adult acute myeloid leukemia; adult acute promyelocytic leukemia (M3)
- Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
ClinicalTrials.gov Identifier: NCT00005825 - Active, not recruiting
stage IIIB non-small cell lung cancer; stage IV non-small cell lung cancer
- Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia
ClinicalTrials.gov Identifier: NCT00016159 - Active, not recruiting
adult acute myeloid leukemia in remission; childhood acute myeloid leukemia in remission; adult acute promyelocytic leukemia (M3); ...
- Chemotherapy and Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastoma
ClinicalTrials.gov Identifier: NCT00017225 - Active, not recruiting
localized resectable neuroblastoma; regional neuroblastoma; disseminated neuroblastoma; stage 4S neuroblastoma; recurrent neuroblastoma; ...
- Phenylbutyrate and Tretinoin in Treating Patients With Hematologic Cancer
ClinicalTrials.gov Identifier: NCT00006239 - Completed
adult acute myeloid leukemia; atypical chronic myeloid leukemia; Chronic Myelomonocytic Leukemia; myelodysplastic and myeloproliferative disease; ...
- Tretinoin in Treating Patients With Mycosis Fungoides or Sezary Syndrome
ClinicalTrials.gov Identifier: NCT00002479 - Completed
stage II cutaneous T-cell lymphoma; stage III cutaneous T-cell lymphoma; stage IV cutaneous T-cell lymphoma; stage I cutaneous T-cell lymphoma
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