|Systematic (IUPAC) name|
|tetrahydrofuran-3-yl [3-[(4-aminophenyl)sulfonyl- (2-methylpropyl) amino] -1-benzyl-2- hydroxy-propyl] aminomethanoate|
|Mol. weight||505.628 g/mol|
|Half life||7.1-10.6 hours|
|Pregnancy cat.|| |
Amprenavir (Agenerase®) is a protease inhibitor used to treat HIV. It was approved by the Food and Drug Administration on April 15, 1999, for twice-a-day dosing instead of needing to be taken every eight hours. The convenient dosing came at a price, as the dose required is 1,200mg, delivered in eight very large gel capsules. Production of amprenavir was discontinued by the manufacturer December 31, 2004.