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Amprenavir

Agenerase 



Article: Amprenavir

2054-220px-amprenavir-amprenavir.png
Amprenavir
Systematic (IUPAC) name
tetrahydrofuran-3-yl [3-[(4-aminophenyl)sulfonyl- (2-methylpropyl) amino] -1-benzyl-2- hydroxy-propyl] aminomethanoate
Identifiers
CAS number 161814-49-9
ATC code J05AE05
PubChem 65016
DrugBank APRD00605
Chemical data
Formula C25H35N3O6S
Mol. weight 505.628 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 90%
Metabolism  ?
Half life 7.1-10.6 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Amprenavir (Agenerase®) is a protease inhibitor used to treat HIV. It was approved by the Food and Drug Administration on April 15, 1999, for twice-a-day dosing instead of needing to be taken every eight hours. The convenient dosing came at a price, as the dose required is 1,200mg, delivered in eight very large gel capsules. Production of amprenavir was discontinued by the manufacturer December 31, 2004.





Retrieved from "http://en.wikipedia.org/wiki/Amprenavir"

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July 29, 2014



Page Updated: July 22, 2006
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